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Acta Metallurgica Sinica(English Letters) 2024年第6期37卷 1007-1018页

作者： Huanzhi Zhang Tianxin Li Qianqian Wang Zhenbo Zhu hefei Huang Yiping Lu Engineering Research Center of High Entropy Alloy Materials(Liaoning Province) School of Materials Science and EngineeringDalian University of TechnologyDalian116024China Shanghai Institute of Applied Physics Chinese Academy of Sciences(CAS)Shanghai201800China

Interstitial strengthening with nitrogen(N)is one of the effective ways to improve the mechanical properties of HEAs,but the effects of N on the microstructures and mechanical properties of the irradiated HEAs have not been studied ***,the microstructures and mechanical properties of N-free and N-doped Ti_(2)ZrNbV_(0.5)Mo_(0.2)HEAs before and after He irradiation were *** results showed that the solid solution strengthening caused by interstitial N improved the yield strength at room temperature and 1023.K without significantly reducing plasticity.N doping significantly promoted the growth,aggregation and wider spatial distribution of He bubbles by enhancing the mobility of He atoms/He-vacancy complexes,with the average size of He bubbles increasing from 10.4 nm in N-free HEA to 3..0 nm in N-doped *** addition,N-doped HEA showed a much higher irradiation hardness increment and hardening fraction than N-free *** to conventional materials doped with N,the introduction of N into Ti_(2)ZrNbV_(0.5)Mo_(0.2)HEA had adverse effects on its resistance to He bubble growth and irradiation *** results of this study indicated that N doping may not improve the irradiation resistance of HEAs.

关键词： High-entropy alloys Nitrogen doping Mechanical properties Helium bubbles Irradiation resistance

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新一轮家电“以旧换新”行动方案影响

日用电器 2024年第3期 1-2页

作者： 1.华创证券 2.光大证券 3.中信期货华创证券光大证券中信期货

国务院印发《推动大规模设备更新和消费品以旧换新行动方案》（以下简称《行动方案》），明确了5方面20项重点任务和实施设备更新、消费品以旧换新、回收循环利用、标准提升四大行动，提出积极开展家电等消费品以旧换新。《行动方案》...

国务院印发《推动大规模设备更新和消费品以旧换新行动方案》（以下简称《行动方案》），明确了5方面20项重点任务和实施设备更新、消费品以旧换新、回收循环利用、标准提升四大行动，提出积极开展家电等消费品以旧换新。《行动方案》家电直接相关内容1.到2027年废旧家电回收量较2023.增长3.%,

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环境污染强制责任保险实施策略及其影响因素

经济地理 2024年第3期44卷 138-146页

作者：黄鹤菲米运生华南农业大学经济管理学院广东广州510642

环境污染强制责任保险(即“环强险”)是一种利用市场机制化解突发环境事件风险、防治环境污染的创新型金融措施,对实现经济社会高质量发展具有重要意义。文章运用不完全信息动态博弈模型,分析了政府、企业、保险公司作为决策主体参与环... 详细信息

环境污染强制责任保险(即“环强险”)是一种利用市场机制化解突发环境事件风险、防治环境污染的创新型金融措施,对实现经济社会高质量发展具有重要意义。文章运用不完全信息动态博弈模型,分析了政府、企业、保险公司作为决策主体参与环境污染强制责任保险的最优策略和均衡条件,并以深圳市为例进行了实证分析。研究发现:(1)政府制定的企业责任分担因子与环境事故风险和损失呈负相关,保费与保险公司责任分担因子呈正相关,企业投保概率与企业责任分担因子呈正相关。(2)深圳市作为中国较早一批环境污染强制责任保险试点示范城市,其责任分担因子现在为企业承担较多赔偿责任,而保险公司承担较少赔偿责任。(3.根据模型分析结果可知企业投保意愿有限,这与其环强险实际投保概率仅有50%的情况相吻合。在此基础上,提出政府应适当补贴企业和保险公司,针对高风险高损失的产业,由保险公司承担更多责任,并赋予保险公司监督权限,针对企业制定严格的环保标准和罚款制度,要在促使企业主动投保的同时履行环保义务等对策建议。

关键词：环境污染强制责任保险不完全信息动态博弈模型绿色金融企业与保险公司政府高风险高损害产业环境风险管理

Reflection on methodology of the correlation between electromagnetic interference and safety in high-speed railway

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Railway Sciences 2024年第1期3卷 84-96页

作者： Chang Liu Shiwu Yang Yixuan Yang hefei Cao Shanghe Liu Department of Electromagnetic Environmental Effects Technology Studio CRSC Research and Design Institute Group Co.Ltd.BeijingChina School of Traffic and Transportation Shijiazhuang Tiedao UniversityShijiazhuangChina School of Automation and Intelligence Beijing Jiaotong UniversityBeijingChina Infrastructure Technology Research Institute CRSC Research and Design Institute Group Co.Ltd.BeijingChina Research Center for Electromagnetic Environmental Effects Shijiazhuang Tiedao UniversityShijiazhuangChina

Purpose – In the continuous development of high-speed railways, ensuring the safety of the operation controlsystem is crucial. Electromagnetic interference (EMI) faults in signaling equipment may cause transportationinterruptions, delays and even threaten the safety of train operations. Exploring the impact of disturbances onsignaling equipment and establishing evaluation methods for the correlation between EMI and safety isurgently ***/methodology/approach – This paper elaborates on the necessity and significance of studying theimpact of EMI as an unavoidable and widespread risk factor in the external environment of high-speed railwayoperations and continuous development. The current status of research methods and achievements from theperspectives of standard systems, reliability analysis and safety assessment are examined layer by ***, it provides prospects for innovative ideas for exploring the quantitative correlation between EMIand signaling *** – Despite certain innovative achievements in both domestic and international standard systems andrelated research for ensuring and evaluating railway signaling safety, there’s a lack of quantitative and strategic research on the degradation of safety performance in signaling equipment due to EMI. A quantitativecorrelation between EMI and safety has yet to be established. On this basis, this paper proposes considerationsfor research methods pertaining to the correlation between EMI and ***/value – This paper overviews a series of methods and outcomes derived from domestic andinternational studies regarding railway signaling safety, encompassing standard systems, reliability analysisand safety assessment. Recognizing the necessity for quantitatively describing and predicting the impact ofEMI on high-speed railway signaling safety, an innovative approach using risk assessment techniques as abridge to establish the correlation between EMI and signaling safety is proposed.

关键词： Electromagnetic interference Reliability Safety Risk assessment Signaling system High-speed railway

复方碘口腔喷雾原位膜的制备及促口腔溃疡修复评价

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中国药科大学学报 2024年

作者：张小军黄山芩郭潇涵季梦菲沈雁陈大全许颖 1.江苏大学药学院 2.中国药科大学药学院 3.烟台大学药学院江苏大学药学院中国药科大学药学院烟台大学药学院

采用原位凝胶技术，制备了新型复方碘口腔喷雾原位膜，用于发挥缓释作用，并促进口腔溃疡创面修复。首先以喷雾状态和成膜时间为指标，对喷雾药液的处方和工艺进行优化。以成膜时间和药膜黏附性为评价指标对药液混合比例进行考察。并对... 详细信息

采用原位凝胶技术，制备了新型复方碘口腔喷雾原位膜，用于发挥缓释作用，并促进口腔溃疡创面修复。首先以喷雾状态和成膜时间为指标，对喷雾药液的处方和工艺进行优化。以成膜时间和药膜黏附性为评价指标对药液混合比例进行考察。并对最优处方制备的复方碘口腔喷雾药液的药物含量、稳定性、pH、喷雾效果，及原位膜的成膜时间、溶解性、吸湿性、保湿性、体外释放等理化性质进行考察；此外，通过细胞实验考察了成膜材料的生物相容性及复方碘口腔喷雾原位膜的促迁移效果；采用兔口腔溃疡模型，对复方碘口腔喷雾在体成膜效果及促修复效果进行评价。实验结果显示，最优处方制备的药液A和药液B的pH分别为6.21 ± 0.02和 6.42 ± 0.03.符合正常口腔黏膜pH范围；稳定性好，具有良好的喷雾状态；药液B中碘含量为（1.96 ± 0.01）mg/mL；原位膜体外成膜时间为（118.3.± 3.6）s，口腔内成膜时间为（13..3.± 4.6）s；24 h溶解率为（87.3. ± 1.74）%，吸湿率为（124.17 ± 7.13.%，保湿率为（26.85 ± 2.50）%；复方碘口腔喷雾原位膜中碘含量为（47.42 ± 0.3.）mg/g；具有良好的柔韧性和黏附性，并具有一定的缓释效果。细胞实验中，原位膜表现出良好的促成纤维细胞迁移作用。兔口腔溃疡实验表明，复方碘口腔喷雾在体可快速成膜，并可显著促进口腔溃疡修复。本研究所开发的复方碘口腔喷雾原位膜，制备工艺稳定，并可有效促进口腔溃疡创面修复，为口腔黏膜制剂的研究和开发提供了新思路，并具有良好的转化前景。

关键词：口腔喷雾原位膜复方碘口腔溃疡缓释促修复

Comparison study of trapped water in human erythrocytes by EPC and DSC method and its application

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Science China(Technological Sciences) 2004年第3期47卷 343-351页

作者： ZHAO Gang1, HE Liqun1, GUO Xiaojie2, LIU Zhong3. LUO Dawei1,3.& GAO Dayong1,3.1. Cryobiomedical Engineering Research Institute, Department of Thermal Science and Energy Engineering, University of Science and Technology of China, {3. 23.027, China 2. Red Cross Blood Center of {3., {3. 23.022, China 3. Department of Mechanical Engineering, University of Kentucky, Lexington, KY 40506-0108, USA Univ Sci & Technol China Cryobiomed Engn Res Inst Dept Thermal Sci & Energy Engn Hefei 230027 Peoples R China Red Cross Blood Ctr hefei Hefei 230022 Peoples R China Univ Kentucky Dept Mech Engn Lexington KY 40506 USA

The novel differential scanning calorimetry method for determining trapped water volume of human red blood cell during freezing process has been reexamined. Results show that the final erythrocyte volume is 53. of its isotonic volume after freezing to -40℃. An electronic particle counter (MultisizerTM III, Beckman Coulter Inc., USA) was used to measure cell volume changes in response to hypertonic solution. Using this approach, when extracellular solution was 3.86 mOsm, the equilibrium cell volume was found to be 57% of its isotonic value. Both results indicate that 3.%—40% of intracellular water is trapped and cannot respond to osmotic difference between intra- and extracellular solution. These findings are consistent with the published data: at least 20%—3.% of the isotonic cell water volume is retained within RBCs during freezing. Some applications of the values of trapped water are addressed.

关键词： differential scanning calorimeter/DSC, electronic particle counter/EPC, cell volumetric change, red blood cell/RBC/erythrocyte

社会化批注能否提升阅读理解水平？基于个体化和社会化批注对比的实验研究

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中国图书馆学报 2024年

作者：李武艾鹏亚姚琦 1.上海交通大学媒体与传播学院 2.南洋理工大学黄金辉传播与信息学院 3.华东师范大学心理与认知科学学院上海交通大学媒体与传播学院南洋理工大学黄金辉传播与信息学院华东师范大学心理与认知科学学院

社会化批注是用户开展社会化阅读的重要实践活动。借鉴计算机支持的协作学习框架和认知负荷理论，本研究采用实验法比较个体化和社会化批注对读者文本阅读理解水平的影响。实验结果显示，虽然社会化批注并未显著影响自我评估的阅读理解... 详细信息

社会化批注是用户开展社会化阅读的重要实践活动。借鉴计算机支持的协作学习框架和认知负荷理论，本研究采用实验法比较个体化和社会化批注对读者文本阅读理解水平的影响。实验结果显示，虽然社会化批注并未显著影响自我评估的阅读理解水平，但对专家打分的阅读理解水平产生了显著的正向影响。中介分析进一步表明，相对于个体化批注，社会化批注提高了读者的感知阅读支持，后者又提升了自我评估和专家打分的阅读理解水平；与个体化批注相比，社会化批注对读者的感知阅读干扰没有显著影响，而感知阅读干扰对通过两种测量方式获取的阅读理解水平也都没有显著的预测作用。理论层面，本研究有助于更加深入全面地洞察社会化批注对阅读理解水平的影响及其背后的作用机理。实践层面，研究结果对社会化阅读软件（尤其对其批注功能）的设计和完善具有重要的参考作用，也能启发阅读推广者思考如何引导读者利用社会化批注的积极作用提升对文本内容的理解和掌握。表5。参考文献52。

关键词：社会化阅读社会化批注个体化批注阅读理解计算机支持的协作学习框架认知负荷理论

藏羊血红蛋白抗氧化肽模拟酶解筛选及活性验证

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食品与发酵工业 2024年

作者：刘鑫罗唐君韩丽娟桂林生侯生珍孙胜男赵成周 1.青海大学医学部药学系 2.青海大学农牧学院 3.青海大学藏医学院青海大学藏医学院青海大学农牧学院青海大学医学部药学系

Based on the theoretical basis of bioinformatics， this paper used the computer to simulate the enzymatic digestion of Tibetan sheep hemoglobin， using online activity scoring， activity prediction， and molecular docking techniques to screen their antioxidant peptides and verify their antioxidant properties by DPPH free radical and ABTS cationic radical scavenging rate experiments. The amino acid sequences of Tibetan sheep hemoglobin were screened using the Uni Prot database to evaluate its potential bioactivities， ExPASy Peptide Cutter online tool was applied to enzymatically digest the screened peptide chains， Peptide Ranker was applied to score the bioactivity prediction， and the online tools Innovagen， ToxinPred， iBitter-SCM， A11erTOP， and AdmetSAR for solubility， toxicity， bitterness， sensitization and ADMET， molecular docking using Keap1 receptor for activity prediction， and finally validation of the screened antioxidant peptides of Tibetan sheep hemoglobin using DPPH free radical and ABTS cationic radical scavenging rate assay. Results showed that five Tibetan sheep hemoglobin chains contained 20 amino acids， and a total of 258 peptides （485 peptides） were obtained by enzymatic digestion， and 110 peptides （194 peptides） with ratings greater than 0.5 were screened out by the bioactivity scoring system， and 18 peptides with good solubility， non-toxicity， non-bitterness， and non-allergenicity were obtained through the prediction of their activities， and the molecular docking was carried out for the 10 peptides that had a better intestinal absorption， and the top three peptides with molecular docking scores， KRM， FPL， and FL， were subjected to in vitro antioxidant activity assay， and the results showed that the free radical scavenging ability of FPL and KRM exceeded that of the positive control， with IC50of 0.125 0±0.012 3. 0.3.9 1±0.03. 4， 0.256 5±0.014 1，（0.3.4 6±0.047 1） mg/mL， respectively， and the free radical scavenging ability of FL reached 88.90% and 94.40%

关键词：藏羊血红蛋白虚拟酶解模拟筛选抗氧化肽分子对接

自体富血小板血浆通过Notch1调节骨质疏松大鼠骨折愈合

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中国骨质疏松杂志 2024年第2期30卷 181-186,209页

作者：沈灵杰秦超刘合飞南通市海门区人民医院手足外科江苏南通226100

目的探讨自体富血小板血浆(platelet-rich plasma,PRP)对骨质疏松症(osteoporosis,OP)大鼠骨折愈合的影响。方法取SD大鼠60只,按随机数字表法分为正常骨折组、模型组、PRP组、DAPT组(Notch通路抑制剂DAPT)、PRP+DAPT组,每组12只。正常... 详细信息

目的探讨自体富血小板血浆(platelet-rich plasma,PRP)对骨质疏松症(osteoporosis,OP)大鼠骨折愈合的影响。方法取SD大鼠60只,按随机数字表法分为正常骨折组、模型组、PRP组、DAPT组(Notch通路抑制剂DAPT)、PRP+DAPT组,每组12只。正常骨折组用右侧股骨干骨折髓内固定术建立骨折模型,其余各组大鼠采用维甲酸(70 mg/kg)灌胃+右侧股骨干骨折髓内固定术建立OP性骨折模型。PRP组制备自体PRP凝胶溶液,注射至骨折断端之间,DAPT组经尾静脉注射Notch通路抑制剂DAPT,PRP+DAPT组给予PRP的同时,尾静脉注射DAPT。各组给药6周后,用X线观察骨折愈合情况;显微CT(Micro-CT)法检测股骨骨密度、骨体积/总体积、骨小梁数量、骨小梁厚度变化;ELISA法检测血清骨钙素(OCN)、骨性碱性磷酸酶(BAP)、血小板源生长因子(PDGF)、转化生长因子-β(TGF-β)、胰岛素样生长因子1受体(IGF-1R)水平;碱性磷酸酶钙-钴法染色及抗酒石酸酸性磷酸酶(TRAP)染色法分别检测成骨细胞及破骨细胞数目;免疫组化法检测骨痂组织中Notch1阳性表达水平;Western Blot法检测骨痂组织中骨形态发生蛋白(BMP)、骨保护素(OPG)、核因子κB受体活化因子配体(RANKL)蛋白表达。结果与正常骨折组大鼠相比,OP性骨折模型大鼠骨痂形成较少,骨折愈合延迟,血清中成骨活性细胞因子分泌减少,骨体积、骨痂密度、骨小梁数量及厚度均减少,成骨细胞数目形成较少,破骨细胞数目形成较多,Notch1及其介导的BMP、OPG促成骨形成蛋白被抑制,破骨形成相关蛋白RANKL活性升高(P<0.05)。与模型组相比,PRP组可促进骨痂形成及骨愈合、促进成骨形成相关因子表达、激活Notch1,并使其介导的成骨形成途径激活、破骨形成途径减弱(P<0.05)。DAPT可阻断PRP的上述作用。结论自体PRP促进OP性骨折大鼠骨量增加及骨折愈合的作用,可能与促进Notch1通路激活有关。

关键词：自体富血小板血浆骨质疏松症骨折 Notch1通路

Mesozoic-Cenozoic tectonic transition in Kuqa Depression-Tianshan,Northwest China:Evidence from sandstone detrital and geochemical records

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Science China Earth Sciences 2005年第9期48卷 1387-1402页

作者： LI Zhong1, GUO Hong2, WANG Daoxuan3.& LIN Wei1 1. Institute of Geology and Geophysics, Chinese Academy of Sciences, Beijing 100029, China 2. Tarim Oilfield Branch, CNPC, Korla 841000, China 3. hefei University of Industry, Tunxilu 193. hefei 23.009, China 1. Institute of Geology and Geophysics Chinese Academy of Sciences 100029 Beijing Chin 2. Tarim Oilfield Branch CNPC 841000 Korla China 3. hefei University of Industry Tunxilu 193 230009 Hefei Chin

Similar to compositional evolution of sandstone modes and detrital heavy minerals from different profiles in the Kuqa Depression, Northwest China, major element analysis of whole sandstones from the same profiles shows four discontinuous depositional interfaces or periods, respectively corresponding to Lower Triassic\Middle Triassic, Upper Jurassic\Lower Cretaceous, Lower Cretaceous\Paleogene and Miocene\Pliocene, and indicates five-phase evolution during Mesozoic-Cenozoic: (1) From the first to fifth phase, a depositional suite changes from maroon and coarse clastic, through grey-dark grey and fine, red and coarse, red-mottled, interlayered by gypsum, to brown and coarse clastic assemblages, accompanying detrital component evolution in unstable-stable-unstable-very unstable-very unstable assem- blages. It is indicated that carbonate and complex detritus gradually dominate in sandstones in post-Late Jurassic, with rapid reduction of compositional maturity. (2) For major element geo- chemical parameters of whole sandstones, CaO and Fe2 O * 3.MgO contents show a change sequence in high-low-high-higher-highest values, with rapid increasing in post-Late Jurassic. (3. Contra some aggregative indicators for weathering indexes of sandstone detrital component, Al2O3.(CaO+Na2O) and ln(Q/(L+CE)), show a change sequence in low-high-low-lower-lowest ratios, with rapid decreasing in post-Late Jurassic. It is found that sandstone samples of the first, second and later three phases may be distinguished from the A-CN-K and A-CNK-FM diagrams respectively. Therefore, in the Kuqa Depression-Tianshan, the most important discontinuous depositional interface recording paleotectonic and paleoclimatic transition occurred in Early Triassic\Middle Triassic and Late Jurassic\Early Cretaceous, respectively, and, however, tec- tonic differentiations of basin-range system finally result in distinct depositional systems but similar detrital weathering indexes across the Lower Cretaceous\Paleogene

关键词： Tianshan, Kuqa Depression, basin-range, depositional record, tectonic transition, Mesozoic-Cenozoic.