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Fluorescent Probes for Cysteine and Cysteine Oxidation Imaging

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Chemical Research in Chinese Universities 2024年第2期40卷 225-236页

作者： ZHang Xia LI Guocheng PAN Wei LI na LI Yanhua Tang Bo College of Chemistry Chemical Engineering and Materials ScienceKey Laboratory of Molecular and Nano ProbesMinistry of EducationCollaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of ShandongInstitute of Molecular and Nano ScienceShandong Normal UniversityJinan250014P.R.China Laoshan Laboratory Qingdao266237P.R.China

Cysteine is an important regulator of redox *** to the nucleophilic and oxidative sensitivity,cysteine residues in proteins can be oxidized by intracellular reactive oxygen species(ROS),which can lead to protein structural and functional ***,the development of fluorescent probes to image cysteine and cysteine oxidation is of great significance for the study of redox homeostasis in living *** this review,the development of fluorescent probes for imaging cysteine and cysteine oxidation was ***,we further analyzed defects of the reported fluorescent probes and made suggestions for the future development of fluorescent *** expect that this review can not only provide a deeper understanding of the role of cysteine and cysteine oxidation in oxidative stress,but also broaden the application of fluorescent probes in imaging cysteine and cysteine oxidation.

关键词： Cysteine Cysteine oxidation Fluorescent probe Oxidative stress

Response of Bacterial Community and Enzyme Activity of Greenhouse Tomato under Different Irrigation Systems

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Phyton-International Journal of Experimental Botany 2024年第7期93卷 1543-1568页

作者： Haijian Yang Mingzhi Zhang na Xiao Yuan Li Faculty of Engineering Huanghe Science and Technology UniversityZhengzhou450063China Northwest Land and Resources Research Center Shaanxi Normal UniversityXi’an710119China

The micro-sprinkler irrigation mulched(MSM)has been suggested as a novel water-saving approach in con-trolled environment ***,the effects of microbial community structure and enzyme activity in the rhizosphere soil on crop growth under MSM remain *** study conducted a randomized experimen-tal design using greenhouse tomatoes to investigate changes in bacterial community structure and enzyme activity in rhizosphere soil under different irrigation frequencies(F)and amounts(I)of ***ﬁndings revealed that with the increase of F or I,The total count of soil bacteria in tomatoesﬁrst rose and then fell in terms of Opera-tional Taxonomic Units(OTUs)classiﬁ*** to other F,the most abundance of nitrogen and phos-phorus metabolism genes and enzyme activities were observed with a 5-day ***,the diversity of soil bacterial community structure initially rose before eventually declining with the increase of the *** 1.00 Epan(cumulative evaporation of a 20 cm standard pan)under MSM helped boost the abundance of nitrogen and phosphorus metabolism functional genes in soil bacteria,ensuring higher enzyme activities related to nitro-gen,carbon,and phosphorus metabolism in the rhizosphere soil of ***’yield initially rose before eventually declining with the increase in F or I,whereas I had a more signiﬁcant effect on yield.A 1.00%increase in I yielded a minimum of 39.24%increase in tomato *** study showed a positive correlation between soil bacterial community,soil enzyme activity,and greenhouse tomato yield under *** the results comprehensively,the combined irrigation mode of F of 5 d and I of 1.00 Epan was recommended for greenhouse tomatoes under *** conclusion provides theoretical support for water-saving practices and yield improve-ment in facility agriculture,especially tomato cultivation.

关键词： Greenhouse tomato yield bacterial community enzyme activity model

Tofacitinib for ulcerative colitis: A promising treatment option

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World Journal of Gastroenterology 2024年第40期30卷 4386-4392页

作者： Zong-Qiang Han Li-na Wen Department of Laboratory Medicine Beijing Xiaotangshan HospitalBeijing 102211China Department of Clinical Nutrition Beijing Shijitan HospitalCapital Medical UniversityBeijing 100038China

A single center retrospective clinical study revealed the efficacy and safety of tofa-citinib in the treatment of ulcerative colitis(UC).This study has clinical reference value but also has some *** studies,including this clinical trial,have shown that tofacitinib could be a promising treatment option for UC,but further clinical research is required to prove this point.

关键词： Tofacitinib Ulcerative colitis Efficacy Safety Clinical trials

Microstructure design of advanced magnesium-air battery anodes

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Journal of Magnesium and Alloys 2024年第2期12卷 443-464页

作者： Xu Huang Qingwei Dai Qing Xiang na Yang Gaopeng Zhang Ao Shen Wanming Li School of Metallurgy and Materials Engineering Chongqing University of Science and TechnologyChongqing 401331China School of Materials and Architectural Engineering Guizhou Normal UniversityGuiyang 550025China School of Material and Metallurgy University of Science and Technology LiaoningAnshan 114051China

Metal-air battery is an environmental friendly energy storage system with unique open ***(Mg)and its alloys have been extensively attempted as anodes for air batteries due to high theoretical energy density,low cost,and ***,the study on Mg-air battery(MAB)is still at the laboratory level currently,mainly owing to the low anodic efficiency caused by the poor corrosion *** order to reduce corrosion losses and achieve optimal utilization efficiency of Mg anode,the design strategies are reviewed from microstructure ***,the corrosion behaviors have been discussed,especially the negative difference effect derived by hydrogen *** attention is given to the effect of anode micro-structures on the MAB,which includes grain size,grain orientation,second phases,crystal structure,twins,and *** further improvement,the discharge performance,long period stacking ordered phase and its enhancing effect are ***,given the current debates over Mg dendrites,the potential risk,the impact on discharge,and the elimination strategies are *** control and single crystal would be promising ways for MAB anode.

关键词： Magnesium Air battery Anode Microstructure Anodic efficiency

Incidence and risk factors of depression in patients with metabolic syndrome

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World Journal of Psychiatry 2024年第2期14卷 245-254页

作者： Li-na Zhou Xian-Cang Ma Wei Wang Department of Psychiatry The First Affiliated Hospital of Xi’an Jiaotong UniversityXi’an 710061Shaanxi ProvinceChina

BACKGROUND Many studies have explored the relationship between depression and metabolic syndrome(MetS),especially in older *** has entered an aging ***,there are still few studies on the elderly in Chinese *** To investigate the incidence and risk factors of depression in MetS patients in China's Mainland and to construct a predictive *** Data from four waves of the China Health and Retirement Longitudinal Study were selected,and middle-aged and elderly patients with MetS(n=2533)were included based on the first *** to the center for epidemiological survey-depression scale(CESD),participants with MetS were divided into depression(n=938)and non-depression groups(n=1595),and factors related to depression were screened ***,the 2-,4-,and 7-year follow-up data were analyzed,and a prediction model for depression in MetS patients was *** The prevalence of depression in middle-aged and elderly patients with MetS was 37.02%.The prevalence of depression at the 2-,4-,and 7-year follow-up was 29.55%,34.53%,and 38.15%,*** prediction model,constructed using baseline CESD and Physical Self-Maintenance Scale scores,average sleep duration,number of chronic diseases,age,and weight had a good predictive effect on the risk of depression in MetS patients at the 2-year follow-up(area under the curve=0.775,95%confidence interval:0.750-0.800,P<0.001),with a sensitivity of 68%and a specificity of 74%.CONCLUSION The prevalence of depression in middle-aged and elderly patients with MetS has increased over *** early identification of and intervention for depressive symptoms requires greater attention in MetS patients.

关键词： Depression Metabolic syndrome Prevalence Risk factor

An improved deep dilated convolutional neural network for seismic facies interpretation

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Petroleum Science 2024年第3期21卷 1569-1583页

作者： na-Xia Yang Guo-Fa Li Ting-Hui Li Dong-Feng Zhao Wei-Wei Gu State Key Laboratory of Petroleum Resources and Engineering CNPC Key Lab of Geophysical ExplorationChina University of Petroleum(Beijing)Beijing 102249China Dagang Branch Research InstituteBGPTianjin300280China

With the successful application and breakthrough of deep learning technology in image segmentation,there has been continuous development in the field of seismic facies interpretation using convolutional neural *** intelligent and automated methods significantly reduce manual labor,particularly in the laborious task of manually labeling seismic ***,the extensive demand for training data imposes limitations on their wider *** overcome this challenge,we adopt the UNet architecture as the foundational network structure for seismic facies classification,which has demonstrated effective segmentation results even with small-sample training ***,we integrate spatial pyramid pooling and dilated convolution modules into the network architecture to enhance the perception of spatial information across a broader *** seismic facies classification test on the public data from the F3 block verifies the superior performance of our proposed improved network structure in delineating seismic facies *** analysis against the traditional UNet model reveals that our method achieves more accurate predictive classification results,as evidenced by various evaluation metrics for image ***,the classification accuracy reaches an impressive 96%.Furthermore,the results of seismic facies classification in the seismic slice dimension provide further confirmation of the superior performance of our proposed method,which accurately defines the range of different seismic *** approach holds significant potential for analyzing geological patterns and extracting valuable depositional information.

关键词： Seismic facies interpretation Dilated convolution Spatial pyramid pooling Internal feature maps Compound loss function

A Joint Estimation Method of SOC and SOH for Lithium-ion Battery Considering Cyber-Attacks Based on GA-BP

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Computers, Materials & Continua 2024年第9期80卷 4497-4512页

作者： Tianqing Yuan na Li Hao Sun Sen Tan Key Laboratory of Modern Power System Simulation and Control&Renewable Energy Technology Ministry of EducationNortheast Electric Power UniversityJilin132012China Department of Electrical Engineering Northeast Electric Power UniversityJilin132012China College of Information and Control Engineering Jilin Institute of Chemical TechnologyJilin132022China Center for Research on Microgrids Department of EnergyAalborg UniversityAalborg9220Denmark

To improve the estimation accuracy of state of charge(SOC)and state of health(SOH)for lithium-ion batteries,in this paper,a joint estimation method of SOC and SOH at charging cut-off voltage based on genetic algorithm(GA)combined with back propagation(BP)neural network is proposed,the research addresses the issue of data manipulation resulting ***,anomalous data stemming fromcyber-attacks are identified and eliminated using the isolated forest algorithm,followed by data ***,the incremental capacity(IC)curve is derived fromthe restored data using theKalman filtering algorithm,with the peak of the ICcurve(ICP)and its corresponding voltage serving as the health factor(HF).Thirdly,the GA-BP neural network is applied to map the relationship between HF,constant current charging time,and SOH,facilitating the estimation of SOH based on ***,SOC estimation at the charging cut-off voltage is calculated by inputting the SOH estimation value into the trained model to determine the constant current charging time,and by updating the maximum available *** show that the root mean squared error of the joint estimation results does not exceed 1%,which proves that the proposed method can estimate the SOC and SOH accurately and stably even in the presence of false data injection attacks.

关键词： Lithium-ion batteries state of charge state of health cyber-attacks genetic algorithm back propagation neural network

CRBFT:A Byzantine Fault-Tolerant Consensus Protocol Based on Collaborative Filtering Recommendation for Blockchains

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Computers, Materials & Continua 2024年第7期80卷 1491-1519页

作者： Xiangyu Wu Xuehui Du Qiantao Yang Aodi Liu na Wang Wenjuan Wang He’nan Province Key Laboratory of Information Security Information Engineering UniversityZhengzhou450000China School of Cyber Science Engineering Zhengzhou UniversityZhengzhou450000China

Blockchain has been widely used in finance,the Internet of Things(IoT),supply chains,and other scenarios as a revolutionary *** protocol plays a vital role in blockchain,which helps all participants to maintain the storage state ***,with the improvement of network environment complexity and system scale,blockchain development is limited by the performance,security,and scalability of the consensus *** address this problem,this paper introduces the collaborative filtering mechanism commonly used in the recommendation system into the Practical Byzantine Fault Tolerance(PBFT)and proposes a Byzantine fault-tolerant(BFT)consensus protocol based on collaborative filtering recommendation(CRBFT).Specifically,an improved collaborative filtering recommendation method is designed to use the similarity between a node’s recommendation opinions and those of the recommender as a basis for determining whether to adopt the recommendation *** can amplify the recommendation voice of good nodes,weaken the impact of cunningmalicious nodes on the trust value calculation,andmake the calculated resultsmore *** addition,the nodes are given voting power according to their trust value,and a weight randomelection algorithm is designed and implemented to reduce the risk of *** experimental results show that CRBFT can effectively eliminate various malicious nodes and improve the performance of blockchain systems in complex network environments,and the feasibility of CRBFT is also proven by theoretical analysis.

关键词： Blockchain consensus byzantine fault-tolerant collaborative filtering trust

Research on physical explosion crater model of high-pressure natural gas pipeline

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PETROLEUM RESEARCH 2024年第3期9卷 432-438页

作者： Wang, Dongyuan Xu, Shuiying Wang, Zhao Zhou, Yazhe Gao, na China Petr Pipeline Engn Corp Langfang Peoples R China PipeChina Engn Technol Innovat Co Ltd Tianjin Peoples R China Univ Sci & Technol Beijing Sch Civil & Resource Engn Beijing Peoples R China China Petr Pipeline Bur Engn Co Ltd Int Business Dept Langfang Peoples R China

In this study, Hypermesh and LS-DYna numerical simulation software are used to build a multi domain coupling model of natural gas pipeline, including soil, pipeline, TNT explosive and air domain, and the non-reflection boundary conditions are set for the model. The TNT equivalent method is used to convert the physical explosion amount of natural gas pipeline into 1387.38 kg TNT explosive amount. The simulation results show that the physical explosion of pipeline forms an approximate elliptical crater with a width of 12.68 m and a depth of 4.12 m; the TNT equivalent of the model is corrected by comparing the crater simulation value and the size value of the crater calculated by the PRCI empirical formula under the same laying condition, and the correction coefficient is selected as 0.9, and the corrected TNT equivalent is 1248.64 kg; the modified model crater size is 3.72 m deep and 12.66 m wide, compared with the crater size obtained from the field test, the error of crater depth and width calculated by the modified model simulation is 5.7% and 15.5% respectively. (c) 2024 The Authors. Publishing services provided by Elsevier B.V. on behalf of KeAi Communication Co. Ltd. This is an open access article under the CC BY-NC-ND license (http://***/licenses/ by-nc-nd/4.0/).

关键词： High-pressure natural gas Pipeline Physical explosion Crater Numerical simulation