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Process in laser drilling of deep microholes without taper on metal materials

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Science China(Technological Sciences) 2024年第1期67卷 37-59页

作者： FAN RunZe mei XueSong CUI JianLei State Key Laboratory for Manufacturing Systems Engineering Xi’an Jiaotong UniversityXi’an 710054China

Deep microhole machining is currently a prominent research area within the aerospace field,encompassing blade film cooling and fuel injection control ***,taper defects in metal materials may lead to performance degradation or even structural damage over a component’s *** and helical drilling,facilitated by ultrashort pulse lasers,have proven more suitable for achieving high-precision,deep holes in metal ***,excessive repetition rates can also result in severe thermal *** methods are commonly employed for controlling taper,including parameter optimization,assistance,and secondary *** laser beam drilling is widely utilized and has been integrated into relevant machining systems for commercial *** deep microholes include film cooling holes and injection *** drilling is a potential machining method for new materials in the aerospace *** laser drilling processing has been studied,numerous related scientific challenges and technical difficulties must be addressed before practical implementation.

关键词： aerospace laser drilling deep microhole taper control

Metadherin promotes stem cell phenotypes and correlated with immune infiltration in hepatocellular carcinoma

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World Journal of gastroenterology 2024年第8期30卷 901-918页

作者： Yi-Ying Wang mei-mei Shen Jian gao Department of gastroenterology The Second Affiliated Hospital of Chongqing Medical UniversityChongqing 400010China Department of gastroenterology and Hepatology The Second Affiliated Hospital of Chongqing Medical UniversityChongqing 400010China

BACKgROUND Metadherin(MTDH)is a key oncogene in most cancer types,including hepato-cellular carcinoma(HCC).Notably,MTDH does not affect the stemness pheno-type or immune infiltration of *** To explore the role of MTDH on stemness and immune infiltration in *** MTDH expression in HCC tissues was detected using TCgA and gEO *** was used to analyze the tissue *** was stably knocked down or overexpressed by lentiviral transfection in the two HCC cell *** invasion and migration abilities of HCC cells were evaluated using Matrigel invasion and wound healing ***,we obtained liver cancer stem cells from the spheroids by culturing them in a serum-free *** expression was determined by western blotting and quantitative reverse transcri-ption *** cytometry,immunofluorescence,and tumor sphere formation assays were used to characterize stem-like *** effects of MTDH inhibition on tumor growth were evaluated in *** correlation of MTDH with immune cells,immunomodulators,and chemokines was analyzed using ssgSEA and TISIDB *** HCC tissues expressed higher levels of MTDH than normal liver *** MTDH expression was associated with a poor *** cells overex-pressing MTDH exhibited stronger invasion and migration abilities,exhibited a stem cell-like phenotype,and formed spheres;however,MTDH inhibition attenuated these *** inhibition suppressed HCC progression and CD133 expression in *** was positively correlated with immature dendritic,T helper 2 cells,central memory CD8^(+)T,memory B,activated dendritic,natural killer(NK)T,NK,activated CD4^(+)T,and central memory CD4^(+)T *** was negatively correlated with activated CD8^(+)T cells,eosinophils,activated B cells,monocytes,macrophages,and mast cells.A positive correlation was observed between the MTDH level and CXCL2 expression,whereas a negative correlation was observed between the MTDH level and CX3CL1 a

关键词： Metadherin Hepatocellular carcinoma Cancer stem cells Immune infiltration

global existence and large-time behavior for primitive equations with the free boundary

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Science China Mathematics 2024年第10期67卷 2303-2330页

作者： hai-Liang Li Chuangchuang Liang School of Mathematical Sciences Capital Normal UniversityBeijing 100048China Academy for Multidisciplinary Studies Capital Normal UniversityBeijing 100048China College of Mathematics and Statistics Chongqing UniversityChongqing 401331China

In the present paper, the primitive equations, which can be used to simulate the large-scale motion of the ocean and atmosphere, are considered in the three-dimensional domain bounded below by a fixed solid boundary and above by a free-moving boundary. The global existence and uniqueness of strong solutions are established, and the long-time convergence to the equilibrium state is shown to be either at an exponential rate for the horizontal periodic domain or at an algebraic rate for the horizontal whole space.

关键词： primitive equations the free boundary value problem global well-posedness large-time behavior

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Cyclohexanol optimizes Pt/ionomer interface in fuel cell cathodes

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Science China Chemistry 2024年第2期67卷 417-419页

作者： Lei Tong hai-Wei Liang Hefei National Research Center for Physical Sciences at the Microscale Department of ChemistryUniversity of Science and Technology of ChinaHefei230026China

This highlight is based on a recent article published in Nature Catalysis, in which Wei's group [1] from Chongqing University proposes a novel approach to enhance the performance of proton exchange membrane fuel cells(PEMFCs)by adjusting the interface between Pt and ionomer in the cathode catalyst layer. Their strategy involves adding cyclohexanol to the cathode catalyst ink to impede the adsorption of sulfonate groups from the ionomer onto Pt nanoparticles, which results in the release of Pt activity sites and a significant improvement in the mass transport efficiency.

关键词： interface catalyst adding

Learning topological defects formation with neural networks in a quantum phase transition

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Communications in Theoretical Physics 2024年第5期76卷 68-76页

作者： Han-Qing Shi hai-Qing Zhang Center for gravitational Physics Department of Space ScienceBeihang UniversityBeijing 100191China Peng Huanwu Collaborative Center for Research and Education Beihang UniversityBeijing 100191China

Neural networks possess formidable representational power,rendering them invaluable in solving complex quantum many-body *** they excel at analyzing static solutions,nonequilibrium processes,including critical dynamics during a quantum phase transition,pose a greater challenge for neural *** address this,we utilize neural networks and machine learning algorithms to investigate time evolutions,universal statistics,and correlations of topological defects in a one-dimensional transverse-field quantum Ising ***,our analysis involves computing the energy of the system during a quantum phase transition following a linear quench of the transverse magnetic field *** excitation energies satisfy a power-law relation to the quench rate,indicating a proportional relationship between the excitation energy and the kink ***,we establish a universal power-law relationship between the first three cumulants of the kink numbers and the quench rate,indicating a binomial distribution of the ***,the normalized kink-kink correlations are also investigated and it is found that the numerical values are consistent with the analytic formula.

关键词： neural networks machine learning transverse-field quantum Ising model kibble-zurek mechanism

Bioleaching of vanadium from stone coal vanadium ore by Bacillus mucilaginosus:Influencing factors and mechanism

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International Journal of Minerals,Metallurgy and Materials 2024年第8期31卷 1828-1838页

作者： Yingbo Dong Jinyu Zan hai Lin School of Energy and Environmental Engineering University of Science and Technology BeijingBeijing 100083China Beijing Key Laboratory on Resource-oriented Treatment of Industrial Pollutants Beijing 100083China

Vanadium and its derivatives are used in various industries,including steel,metallurgy,pharmaceuticals,and aerospace *** China has massive reserves of stone coal resources,these resources have low ***,the effective extraction and recovery of metallic vanadium from stone coal is an important way to realize the efficient resource utilization of stone coal vanadium ***,Bacillus mucilaginosus was selected as the leaching *** vanadium leaching rate reached 35.5%after 20 d of bioleaching under optimal operating *** cumulative vanadium leaching rate in the contact group reached 35.5%,which was higher than that in the noncontact group(9.3%).The metabolites of ***,such as oxalic,tartaric,citric,and malic acids,dominated in bioleaching,accounting for 73.8%of the vanadium leaching ***,during leaching,the presence of stone coal stimulated the expression of carbonic anhydrase in bacterial cells,and enzyme activity increased by 1.335-1.905 *** activity positively promoted the production of metabolite organic acids,and total organic acid content increased by 39.31 mg·L^(-1),resulting in a reduction of 2.51 in the pH of the leaching system with stone *** effect favored the leaching of vanadium from stone *** force microscopy illustrated that bacterial leaching exacerbated corrosion on the surface of stone coal beyond 10 *** study provides a clear and promising strategy for exploring the bioleaching mechanism from the perspective of microbial enzyme activity and metabolites.

关键词： Bacillus mucilaginosus stone coal vanadium ore bioleaching carbonic anhydrase organic acids

Derivation of Expanded Isospectral-Nonisospectral Integrable Hierarchies via the Column-vector Loop Algebra

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Acta Mathematicae Applicatae Sinica 2024年第3期40卷 778-800页

作者： hai-feng WANg Yu-feng ZHANg School of Science Jimei UniversityXiamen 361021China School of Mathematics China University of Mining and TechnologyXuzhou 221116China

A scheme for generating nonisospectral integrable hierarchies is *** on the method,we deduce a nonisospectral hierarchy of soliton equations by considering a linear spectral *** follows that the corresponding expanded isospectral and nonisospectral integrable hierarchies are deduced based on a 6 dimensional complex linear space ■.By reducing these integrable hierarchies,we obtain the expanded isospectral and nonisospectral derivative nonlinear Schr?dinger *** using the trace identity,the biHamiltonian structure of these two hierarchies are also ***,some symmetries and conserved quantities of the resulting hierarchy are discussed.

关键词： expanded isospectral-nonisospectral integrable hierarchies column-vector loop algebra bi-Hamiltonian structure symmetry

Variations, effectiveness and its associated factors of a nationwide web-based hypertension management training project in China: insights from a government-led campaign for 1.2 million lay health workers

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Journal of geriatric Cardiology 2024年第7期21卷 733-750页

作者： Wei WANg hai-Bo ZHANg Jia-Min LIU Yan LI Na TIAN Lei YAN Jin-Xiao SONg mei-Li LI Yue PENg Jing LI National Primary Health Care Hypertension Management Office National Clinical Research Center for Cardiovascular DiseasesNHC Key Laboratory of Clinical Research for Cardiovascular MedicationsFuwai HospitalNational Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina

OBJECTIVES To evaluate the effectiveness of a large-scale,web-based,in-service hypertension management training project among lay health workers(LHWs) at primary care health(PHC) settings in China,and to examine the factors contributing to the variations of *** We used data from a web-based national hypertension management training project implemented in 2018,it was designed to facilitate LHWs to learn,understand,and apply the relevant knowledge and skills in hypertension management through providing training courses by use of the web-based platform with unified *** LHWs were required to participate in the exams before and after training to acquire scores for the use of evaluating their performance of hypertension management *** first used descriptive analysis to present the variations of effectiveness in hypertension management knowledge among LHWs by important ***,we used multilevel logistic regression to examine the individual and regional factors contributing to the variations and quantify the magnitude of how these factors affected training *** There were 1,208,610 LHWs who completed training and were ***,the scores of LHWs increased significantly from 62.87 ± 21.14 out of 100 in the pre-test to 88.30 ± 11.31 in the post-test by 25.43(95% confidence interval[CI]:25.40-25.47).Training contents involved in antihypertensive medication showed the lowest score(54.36) in the pre-test and soared the most after training,up to 84.22 by 54.94%.Individual factors associated with disparities in the knowledge of hypertension management decreased substantially after training,which included sex,age,education,practice type,professional level,and hierarchy of working *** variations were shown at the provincial level,with the majority of them being explained by factors at the regional *** Accessible web-based training modality,government efforts,accompa

关键词： hypertension workers nationwide

Fatigue-resistant Hydrogels

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Chemical Research in Chinese Universities 2024年第1期40卷 64-77页

作者： LI Luofei LEI hai CAO Yi Collaborative Innovation Center of Advanced Microstructures National Laboratory of Solid State MicrostructureDepartment of PhysicsNanjing UniversityNanjing 210093P.R.China Department of Physics Zhejiang UniversityHangzhou 310027P.R.China

Hydrogels have been extensively studied for applications in various fields, such as tissue engineering and soft robotics, as determined by their mechanical properties. The mechanical design of hydrogels typically focuses on the modulus, toughness, and deformability. These characteristics play important roles and make great achievements for hydrogel use. In recent years, a growing body of research has concentrated on the fatigue property of hydrogels, which determines their resistance to crack propagation in the networks during cyclic mechanical loads for applications. However, knowledge of hydrogel fatigue behavior remains notably deficient. Here, we present a brief overview of the fatigue behavior of hydrogels, encompassing the general experimental methods to measure the fatigue property and fundamental theoretical calculation models. Then, we highlight multiple strategies to enhance the fatigue resistance of hydrogels. Finally, we present our perspectives on fatigue-resistant hydrogels, outstanding challenges and potential directions for future research.

关键词： Hydrogel Fatigue-resistant Fracture