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Identification and fine mapping of qSW2.for leaf slow wilting in soybean

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The Crop Journal 2024年第1期12卷 244-251页

作者： Shengyou Li Changling Wang Chunjuan Yan Xugang Sun Lijun Zhang Yongqiang Cao Wenbin Wang shuhong Song Institute of Crop Research Liaoning Academy of Agricultural SciencesShenyang 110161LiaoningChina

Drought is one of the abiotic stresses limiting the production of soybean(Glycine max).Elucidation of the genetic and molecular basis of the slow-wilting(SW)trait of this crop offers the prospect of its genetic improvement.A panel of 188 accessions and a set of recombinant inbred lines produced from a cross between cultivars Liaodou 14 and Liaodou 2. were used to identify quantitative-trait loci(QTL)associated with *** were genotyped by Specific-locus amplified fragment sequencing and seedling leaf wilting was assessed under three water-stress treatments.A genome-wide association study identified 2. SW-associated single-nucleotide polymorphisms(SNPs),including three located in a 2.8-kb linkage-disequilibrium(LD)block on chromosome *** mapping revealed a major-effect QTL,qSW2.associated with all three treatments and adjacent to the LD *** mapping in a BC_(2.F_(3) population derived from a backcross between Liaodou 2. and R2. confined qSW2.to a 60-kb *** expression and sequence variation analysis identified the gene Glyma.02.g2.8100,encoding an auxin transcription factor,as a candidate gene for *** results will contribute significantly to improving drought-resistant soybean cultivars by providing genetic information and resources.

关键词： Drought GWAS Linkage mapping Slow wilting Soybean(Glycine max)

Characterizing structural variants based on graph-genotyping provides insights into pig domestication and local adaption

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Journal of Genetics and Genomics 2024年第4期51卷 394-406页

作者： Xin Li Quan Liu Chong Fu Mengxun Li Changchun Li Xinyun Li shuhong Zhao Zhuqing Zheng Key Lab of Agricultural Animal Genetics Breeding and Reproduction of Ministry of Education and Key Laboratory of Swine Genetics and Breeding of Ministry of AgricultureCollege of Animal Science and TechnologyHuazhong Agricultural UniversityWuhanHubei 430070China Institute of Agricultural Biotechnology Jingchu University of TechnologyJingmenHubei 448000China The Cooperative Innovation Center for Sustainable Pig Production WuhanHubei 430070China Hubei Hongshan Laboratory WuhanHubei 430070China

Structural variants(SVs),such as deletions(DELs)and insertions(INSs),contribute substantially to pig genetic diversity and phenotypic *** a library of SVs discovered from long-read primary assemblies and short-read sequenced genomes,we map pig genomic SVs with a graph-based method for re-genotyping SVs in 402.*** results demonstrate that those SVs harboring specific trait-associated genes may greatly shape pig domestication and local *** characterization of SVs reveals that some population-stratified SVs may alter the transcription of genes by affecting regulatory *** identify that the genotypes of two DELs(2.6-bp DEL,chr7:52.172.101e52.172.397;2.8-bp DEL,chr18:2.,840,143 e2.,840,42.)located in muscle-specific enhancers are associated with the expression of target genes related to meat quality(FSD2.and muscle fiber hypertrophy(LMOD2.and WASL)in *** results highlight the role of SVs in domestic porcine evolution,and the identified candidate functional genes and SVs are valuable resources for future genomic research and breeding programs in pigs.

关键词： Pigs Structural variation Selection signatures Regulatory elements

High-resolution mid-infrared single-photon upconversion ranging

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Photonics Research 2024年第6期12卷 1294-1302页

作者： shuhong JIANG KUN HUANG TINGTING YU JIANAN FANG BEN SUN YAN LIANG QIANG HAO E.WU MING YAN HEPING ZENG State Key Laboratory of Precision Spectroscopy East China Normal UniversityShanghai 200062China Chongqing Key Laboratory of Precision Optics Chongqing Institute of East China Normal UniversityChongqing 401121China Collaborative Innovation Center of Extreme Optics Shanxi UniversityTaiyuan 030006China School of Optical Electrical and Computer Engineering University of Shanghai for Science and TechnologyShanghai 200093China Shanghai Research Center for Quantum Sciences Shanghai 201315China Guangyang Bay Laboratory Chongqing Institute for Brain and IntelligenceChongqing 400064China

Single-photon laser ranging has widespread applications in remote sensing and target ***,highly sensitive light detection and ranging(lidar)has long been restricted in the visible or near-infrared *** appealing quest is to extend the operation wavelength into the mid-infrared(MIR)region,which calls for an infrared photon-counting system at high detection sensitivity and precise temporal ***,we devise and demonstrate an MIR upconversion lidar based on nonlinear asynchronous optical ***,the infrared probe is interrogated in a nonlinear crystal by a train of pump pulses at a slightly different repetition rate,which favors temporal optical scanning at a picosecond timing resolution and a kilohertz refreshing rate ***,the cross-correlation upconversion trace is temporally stretched by a factor of 2.10^(4),which can thus be recorded by a low-bandwidth silicon *** combination with the time-correlated photon-counting technique,the achieved effective resolution is about two orders of magnitude better than the timing jitter of the detector itself,which facilitates a ranging precision of 4μm under a low detected flux of 8×10^(−5) photons per *** presented MIR time-of-flight range finder is featured with single-photon sensitivity and high positioning resolution,which would be particularly useful in infrared sensing and imaging in photon-starved scenarios.

关键词： resolution lidar repetition

Long-term Variation of the Solar Polar Magnetic Fields at Different Latitudes

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Research in Astronomy and Astrophysics 2024年第7期24卷 190-197页

作者： shuhong Yang Jie Jiang Zifan Wang Yijun Hou Chunlan Jin Qiao Song Yukun Luo Ting Li Jun Zhang Yuzong Zhang Guiping Zhou Yuanyong Deng Jingxiu Wang National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China School of Astronomy and Space Science University of Chinese Academy of SciencesBeijing 100049China State Key Laboratory of Solar Activity and Space Weather National Space Science CenterChinese Academy of SciencesBeijing 100190China School of Space and Environment Beihang UniversityBeijing 102206China Key Laboratory of Space Weather National Satellite Meteorological Center(National Center for Space Weather)China Meteorological AdministrationBeijing 100081China Innovation Center for FengYun Meteorological Satellite(FYSIC) Beijing 100081China School of Physics and Materials Science Anhui UniversityHefei 230601China

The polar magnetic fields of the Sun play an important role in governing solar activity and powering fast solar ***,because our view of the Sun is limited in the ecliptic plane,the polar regions remain largely *** the high spatial resolution and polarimetric precision vector magnetograms observed by Hinode from 2.12.to 2.2.,we investigate the long-term variation of the magnetic fields in polar caps at different *** Hinode magnetic measurements show that the polarity reversal processes in the north and south polar caps are *** variation of the averaged radial magnetic flux density reveals that,in each polar cap,the polarity reversal is completed successively from the 70°latitude to the pole,reflecting a poleward magnetic flux migration *** results clarify the polar magnetic polarity reversal process at different latitudes.

关键词： dynamo-Sun magnetic fields-Sun photosphere

Towards carbon neutrality:Sustainable recycling and upcycling strategies and mechanisms for polyethylene terephthalate via biotic/abiotic pathways

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Eco-Environment & Health 2024年第2期3卷 117-130页

作者： Jiaqi Yang Zhiling Li Qiongying Xu Wenzong Liu shuhong Gao Peiwu Qin Zhenglin Chen Aijie Wang School of Civil&Environmental Engineering Harbin Institute of Technology(Shenzhen)Shenzhen 518055China State Key Laboratory of Urban Water Resources and Environment School of EnvironmentHarbin Institute of TechnologyHarbin 150090China Institute of Biopharmaceutical and Health Engineering Shenzhen International Graduate SchoolTsinghua UniversityShenzhen 518055China Tsinghua-Berkeley Shenzhen Institute Tsinghua Shenzhen International Graduate SchoolTsinghua UniversityShenzhen 518055China

Polyethylene terephthalate(PET),one of the most ubiquitous engineering plastics,presents both environmental challenges and opportunities for carbon neutrality and a circular *** review comprehensively addressed the latest developments in biotic and abiotic approaches for PET recycling/***,microbial depolymerization of PET,along with the biosynthesis of reclaimed monomers[terephthalic acid(TPA),ethylene glycol(EG)]to value-added products,presents an alternative for managing PET waste and enables CO_(2.***,thermal treatments(i.e.,hydrolysis,glycolysis,methanolysis,etc.)and photo/electrocatalysis,enabled by catalysis advances,can depolymerize or convert PET/PET monomers in a more flexible,simple,fast,and controllable *** abiotic/biotic catalysis offers great potential for PET upcycling to generate commodity chemicals and alternative materials,ideally at lower energy inputs,greenhouse gas emissions,and costs,compared to virgin polymer ***,over 2. types of upgraded PET products(e.g.,adipic acid,muconic acid,catechol,vanillin,and glycolic acid,etc.)have been identified,underscoring the potential of PET upcycling in diverse *** can be made to develop chemo-catalytic depolymerization of PET,improve microbial depolymerization of PET(e.g.,hydrolysis efficiency,enzymatic activity,thermal and pH level stability,etc.),as well as identify new microorganisms or hydrolases capable of degrading PET through computational and machine learning ***,this review provides a roadmap for advancing PET recycling and upcycling technologies,which hold the potential to shape the future of PET waste management and contribute to the preservation of our ecosystems.

关键词： PET depolymerization Monomers Recycling/upcycling Biocatalysis Photo/electrocatalysis

Hi-Tag:a simple and efficient method for identifying protein-mediated long-range chromatin interactions with low cell numbers

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Science China(Life Sciences) 2024年第5期67卷 1027-1034页

作者： Xiaolong Qi Lu Zhang Qiulin Zhao Peng Zhou Sai Xian Zhang Jingjin Li Zhuqing Zheng Yue Xiang Xueting Dai Zhe Jin Yaobang Jian Xinyun Li Liangliang Fu shuhong Zhao Key Lab of Agricultural Animal Genetics Breeding and Reproduction of Ministry of Education and Key Laboratory of Swine Genetics and Breeding of Ministry of AgricultureCollege of Animal Science and TechnologyHuazhong Agricultural UniversityWuhan 430070China The Cooperative Innovation Center for Sustainable Pig Production Wuhan 430070China Hubei Hongshan Laboratory Frontiers Science Center for Animal Breeding and Sustainable ProductionWuhan 430070China

Protein-mediated chromatin interactions can be revealed by coupling proximity-based ligation with chromatin ***,these techniques require complex experimental procedures and millions of cells per experiment,which limits their widespread application in life science ***,we develop a novel method,Hi-Tag,that identifies high-resolution,long-range chromatin interactions through transposase tagmentation and chromatin proximity ligation(with a phosphorothioate-modified linker).Hi-Tag can be implemented using as few as 100,000 cells,involving simple experimental procedures that can be completed within 1.5 ***,Hi-Tag is capable of using its own data to identify the binding sites of specific proteins,based on which,it can acquire accurate interaction *** results suggest that Hi-Tag has great potential for advancing chromatin interaction studies,particularly in the context of limited cell availability.

关键词： Hi-Tag chromatin interactions transposase tagmentation chromatin proximity ligation low cell numbers

Restoring periodontal tissue homoeostasis prevents cognitive decline by reducing the number of Serpina3nhigh astrocytes in the hippocampus

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The Innovation 2024年第1期5卷 98-108页

作者： Zongshan Shen shuhong Kuang Yong Zhang Jiayao Chen Shuting Wang Congfei Xu Yunjia Huang Min Zhang Shuheng Huang Jun Wang ChuanJiang Zhao Zhengmei Lin Xuetao Shi Bin Cheng Hospital of Stomatology Guangdong Provincial Key Laboratory of StomatologyGuanghua School of StomatologySun Yat-sen UniversityGuangzhou 510060China National Engineering Research Centre for Tissue Restoration and Reconstruction South China University of TechnologyGuangzhou 510006China Key Laboratory of Biomedical Engineering of Guangdong Province South China University of TechnologyGuangzhou 510006China School of Biomedical Science and Engineering South China University of TechnologyGuangzhou 510650China The First Affiliated Hospital Sun Yat-sen UniversityGuangzhou 510080China

Cognitive decline has been linked to periodontitis through an undetermined pathophysiological *** study aimed to explore the mechanism underlying periodontitis-related cognitive decline and identify therapeutic strategies for this *** single-nucleus RNA sequencing we found that changes in astrocyte number,gene expression,and cell‒cell communication were associated with cognitive decline in mice with *** addition,activation of the NOD-like receptor family pyrin domain containing 3(NLRP3)inflammasome was observed to decrease the phagocytic capability of macrophages and reprogram macrophages to a more proinflammatory state in the gingiva,thus aggravating *** further investigate this finding,lipid-based nanoparticles carrying NLRP3 siRNA(NPsiNLRP3)were used to inhibit overactivation of the NLRP3 inflammasome in gingival macrophages,restoring the oral microbiome and reducing periodontal ***,gingival injection of NPsiNLRP3 reduced the number of Serpina3nhigh astrocytes in the hippocampus and prevented cognitive *** study provides a functional basis for the mechanism by which the destruction of periodontal tissues can worsen cognitive decline and identifies nanoparticle-mediated restoration of gingival macrophage function as a novel treatment for periodontitis-related cognitive decline.

关键词： NLRP3 periodontal number

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水中沉底爆炸压力信号时频特征分析

兵器装备工程学报 2024年第6期45卷 47-52,95页

作者：张姝红 91388部队辽宁大连116041

受装药当量变化和海底边界影响,水中沉底爆炸压力信号时频特征和能量分布与小当量装药在自由场条件下爆炸相比具有明显变化。为获取水中沉底爆炸压力信号特征,利用实测压力数据,采用小波分析方法进行分析,得到了信号不同时频下的特征和... 详细信息

受装药当量变化和海底边界影响,水中沉底爆炸压力信号时频特征和能量分布与小当量装药在自由场条件下爆炸相比具有明显变化。为获取水中沉底爆炸压力信号特征,利用实测压力数据,采用小波分析方法进行分析,得到了信号不同时频下的特征和能量分布。分析结果表明:压力信号在4 kHz以下频段能量占比超过95%,2.0 Hz以下频段能量超过75%,2.0 Hz以下频段峰值压力占比为39%,能量和峰值压力分布均向更低的频段集中;冲击波时段能量占比达64%,滞后流时段能量占比为30%,而二次压力波时段能量占比不到6%,爆炸能量主要集中在冲击波和滞后流时段,因此在沉底爆炸条件下舰艇结构和设备抗冲击响应分析时,在频域应重点关注低频段影响,在时域应重点关注冲击波和滞后流时段的影响。

关键词：水中爆炸冲击波压力气泡脉动小波分析时频特征

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高斯:数学史上的伟大心灵

自然辩证法通讯 2024年第2期46卷 113-122页

作者：王淑红河北师范大学数学科学学院河北石家庄050024

卡尔·弗里德里希·高斯在数论、代数、几何、天文学、物理等方面都作出了里程碑式成果。他提出了“数只是我们心灵的产物”的哲学思想。通过研究和分析有关高斯的论著和书信等文献材料,本文主要对高斯的人生经历、成就和哲学信念进行评... 详细信息

卡尔·弗里德里希·高斯在数论、代数、几何、天文学、物理等方面都作出了里程碑式成果。他提出了“数只是我们心灵的产物”的哲学思想。通过研究和分析有关高斯的论著和书信等文献材料,本文主要对高斯的人生经历、成就和哲学信念进行评述,以期人们对高斯有更加深入的了解。

关键词：卡尔·弗里德里希·高斯心灵的产物数论