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Switchable shape memory polymer bio-inspired adhesive and its application for unmanned aerial vehicle landing

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Chinese Journal of Aeronautics 2024年第3期37卷 380-390页

作者： Qingsong HE Zefang ZHAO qiyun ZHONG Siyuan LIU Kai DENG Yongqi LIU Ning ZHANG Zijie ZHAO Fengjiang ZHAN Jianfeng ZHAO Jiangsu Provincial Key Laboratory of Bionic Functional Materials College of Mechanical and Electrical EngineeringNanjing University of Aeronautics and AstronauticsNanjing 210016China Key Laboratory of Advanced Technology for Small and Medium-Sized UAV Ministry of Industry and Information TechnologyUnmanned Aerial Vehicles Research InstituteNanjing University of Aeronautics and AstronauticsNanjing 210016China State Key Laboratory of Mechanics and Control of Aerospace Structures Nanjing University of Aeronautics and AstronauticsNanjing 210016China Functional Morphology and Biomechanics Institute of ZoologyKiel UniversityKiel 24098Germany

Controlled and switchable adhesion is commonly observed in biological *** recent years,many scholars have focused on making switchable bio-inspired ***,making a bio-inspired adhesive with high adhesion performance and excellent dynamic switching properties is still a challenge.A Shape Memory Polymer Bio-inspired Adhesive(SMPBA)was successfully developed,well realizing high adhesion(about 337 kPa),relatively low preload(about90 kPa),high adhesion-to-preload ratio(about 3.74),high switching ratio(about 6.74),and easy detachment,which are attributed to the controlled modulus and contact area by regulating temperature and the Shape Memory Effect(SME).Furthermore,SMPBA exhibits adhesion strength of80–337 kPa on various surfaces(silicon,iron,and aluminum)with different roughness(Ra=0.02.–10.2.0)because of the conformal contact,reflecting outstanding surface *** finite element analysis verifies the bending ability under different temperatures,while the adhesion model analyzes the influence of preload on contact area and ***,an Unmanned Aerial Vehicle(UAV)landing device with SMPBA was designed and manufactured to achieve UAV landing on and detaching from various *** study provides a novel switchable bio-inspired adhesive and UAV landing method.

关键词： Bio-inspired adhesive Shape memory polymers Switchable adhesive Unmanned aerial vehicle Landing

Observation of the failure mechanism in Ag_(10)Ge_(15)Te_(75)-based memristor induced by ion transport

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Nano Research 2024年第9期17卷 8431-8437页

作者： Yuwei Xiong Kuibo Yin Weiwei Sun Jingcang Li Shangyang Shang Lei Xin qiyun Wu Xiaoran Gong Yidong Xia Litao Sun SEU-FEI Nano-Pico Center Key Laboratory of MEMS of Ministry of EducationSoutheast UniversityNanjing 210096China College of Engineering and Applied Sciences Nanjing UniversityNanjing 210093China

The solid-electrolyte-based memristors have attracted tremendous attention for the next-generation nonvolatile memory for both logic and neuromorphic ***,they encounter variability performance challenges which originated from the random ionic transport and conductive filaments ***,the electrochemical metallized mechanism associated with ion transport has been ***,the failure mechanism caused by ion transport during cycles is rarely ***,the five stages of failure in the Ag/Ag_(10)Ge_(15)Te_(75)/W memristor are elucidated through ex-situ current-voltage measurements combined with in-situ transmission electron microscopy *** investigation reveals that the migration and enrichment of Ag ions result in the precipitation of Ag_(2.*** formation of Ag_(2.Te hinders the device's ability to maintain its bipolar characteristics and also decreases the resistance value of the high resistance state,thereby reducing the device's switching *** promising results provide important guidance for the future design of structures and the manipulation of ion transport for high-performance memristors.

关键词： Ag10Ge15Te75 in-situ transmission electron microscopy(TEM) failure mechanism

Engineered extracellular vesicles efficiently deliver CRISPR-Cas9 ribonucleoprotein(RNP)to inhibit herpes simplex virus1 infection in vitro and in vivo

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Acta Pharmaceutica Sinica B 2024年第3期14卷 1362-1379页

作者： Yuanda Wan Liren Li Ruilin Chen Jiajia Han qiyun Lei Zhipeng Chen Xiaodong Tang Wenyu Wu Shuwen Liu Xingang Yao NMPA Key Laboratory for Research and Evaluation of Drug Metabolism Guangdong Provincial Key Laboratory of New Drug ScreeningSchool of Pharmaceutical SciencesSouthern Medical UniversityGuangzhou 510515China Center of Clinical Pharmacy Nanfang HospitalSouthern Medical UniversityGuangzhou 510515China State Key Laboratory of Ophthalmology Zhongshan Ophthalmic CenterSun Yat-sen UniversityGuangzhou 510060China Key Laboratory of Infectious Diseases Research in South China(Southern Medical University) Ministry of EducationGuangzhou 510515China

Extracellular vesicles(EVs)have recently emerged as a promising delivery platform for CRISPR/Cas9 ribonucleoproteins(RNPs),owing to their ability to minimize off-target effects and immune ***,enhancements are required to boost the efficiency and safety of Cas9 RNP enrichment within *** response,we employed the Fc/Spa interaction system,in which the human Fc domain was fused to the intracellular domain of PTGFRN-Δ687 and anchored to the EV ***,the B domain of the Spa protein was fused to the C domain of cargos such as Cre or *** to the robust interaction between Fc and Spa,this method enriched nearly twice the amount of cargo within the *** loaded with spCas9 RNP targeting the HSV1 genome exhibited significant inhibition of viral replication in vitro and in ***,following neuron-targeting peptide RVG modification,the in vivo dosage in neural tissues substantially increased,contributing to the clearance of the HSV1 virus in neural tissues and exhibiting a lower off-target *** findings establish a robust platform for efficient EV-based SpCas9 delivery,offering potential therapeutic advantages for HSV1 infections and other neurological disorders.

关键词： Extracellular vesicles CRISPR/Cas9 Ribonucleoproteins PTGFRN Fc/Spa HSV1 Neuron-targeting Delivery

Spatio-temporal evolution and topographic gradient effect of land use and ecosystem service value in the Lhasa River Basin

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Journal of Mountain Science 2024年第6期21卷 2059-2074页

作者： ZHOU Jianwei FENG Bin WU Hua XU Tong CHEN Linna ZHAO Xinyong GUO qiyun LI Jiatong ZHANG Chenguang ZHU Kangcheng KONG Yuzhong School of Ecology and Environment Tibet UniversityLhasa 850000China School of Engineering Tibet UniversityLhasa 850000China Joint Laboratory of Plateau Surface Remote Sensing Tibet UniversityLhasa 850000China

The Lhasa River Basin forms an essential human settlement area in the southern part of the Qinghai-Tibet *** study employed ecosystem service value(ESV)evaluation model,terrain gradient grading,and Geodetector to analyze land use and ESV in the Lhasa River Basin from 1985 to *** findings reveal that:(1)From 1985 to 2.2.,grassland was the dominant land *** was a trend of grassland reduction and the expansion of other land types.(2.ESV has increased over the research period(with a total increase of 0.84%),with higher values in the southeast and lower values in the *** contributed the most to ESV,and climate regulation and hydrological regulation were the ecosystem services that contribute the most to ESV.(3)Natural factors like NDVI and altitude,as well as economic factors like population density and distance from roads,influenced the spatial differentiation of ESV,the explanatory power of NDVI reached up to *** interaction between factors had a greater impact than individual *** research results can provide theoretical support for national spatial planning and ecological environment protection in the Lhasa River Basin and other similar areas.

关键词： Ecosystem services value Land use Terrain gradient effect Lhasa River Basin Driving factors

论创造社的“转向”及其对现实主义文论的贡献

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中国文学研究 2024年第1期 20-28页

作者：汤奇云深圳大学人文学院广东深圳518060

2.世纪2.年代发生的创造社集体“转向”事件,不能单纯地被看成是一个文学社团的政治抉择,而是中国现代“文心”重构过程中的一个里程碑式事件。创造社是一个自带革命基因和道德纯洁主义倾向的浪漫派社团。他们在现实革命斗争中完成了无... 详细信息

2.世纪2.年代发生的创造社集体“转向”事件,不能单纯地被看成是一个文学社团的政治抉择,而是中国现代“文心”重构过程中的一个里程碑式事件。创造社是一个自带革命基因和道德纯洁主义倾向的浪漫派社团。他们在现实革命斗争中完成了无产阶级集体主义精神的“洗礼”,坚信马克思主义人学所揭示的无产阶级“革命情感”的正义性。在创造“革命文学”这一总目标下,他们率先运用马克思主义唯物论文学史观,与人性论者和写实派作家展开了论争和批评实践,整体性地推动了五四新文学作家对文学的价值、作家的世界观以及创作方法等命题的思考,为建构集体主义美学与现实主义文论铺平了道路。

关键词：马克思主义创造社革命情感“ 唯物的文学论” 新写实主义

基于日本核污染水排海污染损害的社会化救济路径——强制责任保险的可保性和关键问题讨论

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中国人口·资源与环境 2024年第2期34卷 131-141页

作者：田其云韩颖怡中国海洋大学法学院山东青岛266100

日本核污染水排海造成的污染损害赔偿数额巨大,建立系统性救济机制迫在眉睫,其责任保险是社会化救济的重要法律路径。研究认为,核污染水污染责任具有可保性:持续性核污染水排海使损害的潜伏持续累积,几十年后仍将面临难以预期的保险索赔... 详细信息

日本核污染水排海造成的污染损害赔偿数额巨大,建立系统性救济机制迫在眉睫,其责任保险是社会化救济的重要法律路径。研究认为,核污染水污染责任具有可保性:持续性核污染水排海使损害的潜伏持续累积,几十年后仍将面临难以预期的保险索赔,核污染水是一种面向未来的新的保险标的。政府主导构建核污染水强制责任保险制度,可分散核污染水污染风险,确保未来污染损害发生时能为受害人及受损生态系统修复提供财务赔偿保证,填补赔偿环节中作为赔偿者短板的赔偿能力,使得赔偿有序、高效进行,为有效治理海洋环境污染提供保障。为此,应借助政府公权力构建核污染水强制责任保险制度:①通过立法强制核污染水污染责任投保。②面对来自未来的海洋生态损害索赔,将核污染水持续污染纳入强制责任保险范围,明确界定为持续性保险事故,对未来发生的损害赔偿承担保险责任,治理海洋环境污染,修复海洋生态系统。③设立专门的保险公司参与经营可以更好地控制污染风险和经营风险,明确保险公司对核污染水污染风险进行承保的义务及其参与权,通过相关政策为专门保险公司的保险能力建设提供保障。日本政府授意或主导核污染水排海,依国际法需承担损害赔偿责任,应就建立核污染水强制责任保险国际合作进行磋商,包括:日本履行核污染水排海告知义务,放宽利益攸关国保险公司进入日本保险市场的限制,对核污染水强制责任进行共同保险,搭建共同保险信息系统平台,利用保险衍生工具共同推动核污染水巨灾证券化,共同商定核污染水保险准备金的提取比例、留存期限、使用管理,建立长期的、提留充足的核污染水保险准备金以有效应对未来可能发生的巨额索赔。日本与利益攸关国应就核污染水损失评估体系建设进行国际合作,为保险公司核保提供核污染水风险评估、损失评估、损害处理及赔偿等技术支持和专业咨询。

关键词：核污染水排海可保性强制责任保险法律制度

Luteolin， a common flavone in vegetables， acts as a hormetin possessing neurotrophic function: signaling mediated by inducing mitochondrial stress

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Food Science and Human Wellness 2024年

作者： Alex Xiong Gao Tracy Chenxi Xia Maggie Suisui Guo Gary Kawing Yuen Kevin qiyun Wu Tina Tingxia Dong Karl Wah-Keung Tsim Shenzhen Key Laboratory of Edible and Medicinal Bioresources， HKUST Shenzhen Research Institute Division of Life Science and Center for Chinese Medicine， The Hong Kong University of Science and Technology

This study aims to uncover the hormetic process of luteolin， a common dietary flavone， in neuronal cells through its role in inducing mitochondrial stress. In rat pheochromocytoma PC12.cells， luteolin at low concentrations caused a mild and reversible loss of mitochondrial membrane potential (MMP)， while high concentrations of luteolin triggered intense and sustained depolarization of MMP. The MMP disturbance was shown to have a close association with the trophic and/or toxic effects triggered by luteolin; because the common mitochondrial uncouplers shared similar bi-phase dose-response on cell viability， as that of luteolin. Along with the induced MMP pertubation， luteolin triggered the development of autophagy and mitophagy， as determined by mCherry-GFP-LC3B tandem protein， and by the co-localization of mitochondrial/lysosomal staining. Subsequent application of autophagy inhibitors in the cultures blocked the luteolin-induced neurotrophic activities and sensitized the cells to be less resistant to luteolin-mediated cytotoxicity. Other flavonoids also displayed similar properties in the cultures， indicating that these compounds act as hormetic pharmacological inducers that stimulate cells to become more resilient and adapt to threats. This study provides a unifying mechanistic explanation for the neuro-beneficial effects of luteolin and other flavonoids.

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塑料废弃物的电催化升级回收技术

高分子材料科学与工程 2024年第7期40卷 181-190页

作者：鄢维李渊潘其云湖北科技职业学院机电工程学院湖北武汉430074 武汉理工大学光纤传感技术与网络国家工程研究中心湖北武汉430074 湖北科技职业学院电信工程学院湖北武汉430074 湖北师范大学材料科学与工程学院湖北黄石435000

废弃塑料已导致严重的生态环境问题,开发高效、环保和可持续的塑料升级回收技术是近年来备受关注的热点。与传统化学回收方法相比,电催化重整具有低能耗、无污染和高选择性等特点,能够在温和条件下将塑料氧化为小分子单体或高附加值化学... 详细信息

废弃塑料已导致严重的生态环境问题,开发高效、环保和可持续的塑料升级回收技术是近年来备受关注的热点。与传统化学回收方法相比,电催化重整具有低能耗、无污染和高选择性等特点,能够在温和条件下将塑料氧化为小分子单体或高附加值化学品,在废弃物资源化利用等领域有着巨大的应用潜力。文中聚焦塑料电催化氧化技术的最新研究进展,系统总结了电催化重整技术在塑料升级回收方面的应用,着重探讨了各类电催化材料的性能与用途,并展望了塑料废弃物电催化回收技术的未来发展方向。

关键词：塑料废弃物电催化重整高附加值化学品升级回收

论美学的中国化历程——以朱光潜的两次美学论争为线索

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社会科学战线 2024年第3期345卷 145-154页

作者：汤奇云殷国明深圳大学人文学院广东深圳518000 华东师范大学中文系上海200000

自西方美学理论体系和知识谱系输入中国以来,美学就开启了其中国化历程。吕澂从“美的要求”出发,倡导建构一种“全体的美学”,为美学中国化定了基调。然而,“五四”反传统的时代文化心理和东西方在形而上学上的分歧,阻碍了其与中国传... 详细信息

自西方美学理论体系和知识谱系输入中国以来,美学就开启了其中国化历程。吕澂从“美的要求”出发,倡导建构一种“全体的美学”,为美学中国化定了基调。然而,“五四”反传统的时代文化心理和东西方在形而上学上的分歧,阻碍了其与中国传统哲学及审美经验的融通与结合,美学中国化一度陷入了困境。直到朱光潜“情思融会”说的提出和朱鲁之间“静穆美”之争的发生,美学在经历了从美学观念的接受到辩证思维的引进、再到与本土形而上学的接轨三个阶段后,才初步完成其中国化历程,并走上了理论阐释与创作的艺术展示交叉整合的发展道路。

关键词：美学中国化 “美的要求” 朱光潜 “情思融会” 静穆美之争