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THE REALIZATION OF MULTIPLIER HILBERT BIMODULE ON BIDUAL SPACE AND TIETZE EXTENSION THEOREM

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Chinese Annals of Mathematics,Series B 2000年第3期21卷 375-380页

作者： FANG XIAOCHUN(Department of Mathematics, tongji university, shanghai 2.0092. china) E-mail: xfang@*** Department of Mathematics Tongji University Shanghai 200092 China

The multiplier bimodule of Hilbert bimodule is introduced in a way similar to [1], and its realization on a quotient of bidual space and Tietze extension theorem are obtained similar to that in C-algebra case. As a re... 详细信息

关键词： Realization on bidual space Multiplier Hilbert bimodule Tietze extension theorem

Preliminary design and parametric study of 1400 m partially earth-anchored cable-stayed bridge

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Science china(Technological Sciences) 2010年第2期53卷 502-511页

作者： SUN Bin, CHENG Jin & XIAO RuCheng Department of Bridge Engineering, tongji university, shanghai 2.0092. china Department of Bridge Engineering Tongji University Shanghai China

The preliminary design and parametric study of 1400 m partially earth-anchored cable-stayed bridge are described. Static per-formance of this new type of bridge is discussed. Compared with fully self-anchored cable-stayed bridge, its advantages in fin-ished state are summarized. Based on numerical calculation, effects of several structural parameters on static performance are presented.

关键词： partially earth-anchored cable-stayed bridge preliminary design parametric study

Bayesian cognitive trust model based self-clustering algorithm for MANETs

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Science china(Information Sciences) 2010年第3期53卷 494-505页

作者： WANG Wei1,2.3 & ZENG GuoSun1,2.31Department of Computer Science & Technology,{2., shanghai 2.0092. china 2.2. Branch, National Engineering & Technology Center of High Performance Computer, shanghai 2.0092. china 3Key Loboratory of Embedded System and Service Computing, Ministry of Education, shanghai 2.0092. china Department of Computer Science & Technology Tongji University Shanghai China tongji Branch National Engineering & Technology Center of High Performance Computer Shanghai China Key Loboratory of Embedded System and Service Computing Ministry of Education Shanghai China

With the introduction of mobile Ad hoc networks (MANETs), nodes are able to participate in a dynamic network which lacks an underlying infrastructure. Before two nodes agree to interact, they must trust that each will satisfy the security and privacy requirements of the other. In this paper, using the cognition inspired method from the brain informatics (BI), we present a novel approach to improving the search efficiency and scalability of MANETs by clustering nodes based on cognitive trust mechanism. The trust relationship is formed by evaluating the level of trust using Bayesian statistic analysis, and clusters can be formed and maintained autonomously by nodes with only partial knowledge. Simulation experiments show that each node can form and join proper clusters, which improve the interaction performance of the entire network. The essence of the underlying reason is analyzed through the theory of complex networks, revealing great scalability of this method.

关键词： trust model MANET self-clustering Bayesian method cognitive mobile

Identification of glutamate transporters and receptors in mouse testis

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Acta Pharmacologica Sinica 2004年第3期25卷 112-117页

作者： Jia-hua HU,Na YANG2.Ying-hua MA,Jie JIANG,Jin-fu ZHANG3,Jian FEI4,Li-he GUO4 Laboratory of Molecular Cell Biology,Institute of Biochemistry and Cell Biology,shanghai Institutes for Biological Sciences,Chinese Academy of Sciences,shanghai 2.0031 3Department of Urology,{2. Hospital,{2. university,shanghai 2.0065,china 中科院上海生命科学院 Laboratory of Molecular Cell Biology CAS 上海 200031 Department of Urology Tongji Hospital Tongji University 上海 200065

AIM: To investigate the presence of glutamate transporters and receptors in mouse testis. METHODS: Glutamate uptake analysis was performed to study the function of glutamate transporters in mouse testis. Comparative RT-PCR technique and sequencing analysis were used to study the expression of glutamate receptors and transport- ers in mouse testis. RESULTS: Mouse testis possessed glutamate uptake capacity with sodium-dependence. Vmax value of glutamate uptake was (1.60 ± 0.2.) pmol/min per mg protein and Km value of glutamate uptake was (11.0±1.6) μmol/L in mouse testis according to saturation analysis. Furthermore, the uptake activity could be inhibited by DHK (GLT1 selective inhibitor) and THA (glutamate uptake inhibitor). In addition, RT-PCR results revealed that glutamate transporters (GLT1 and EAAC1) and ionotropic glutamate receptors (NR1, NR2., GluR6 and KA2. were expressed in mouse testis. CONCLUSION: Glutamate transporters and receptors do exist in mouse testis.

关键词： glutamates receptors amino acid transport systems testis uptake

Synthesis and Characteristics of an Aspartame Analogue,L-Asparaginyl L-3-Phenyllactic Acid Methyl Ester

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Acta Biochimica et Biophysica Sinica 2004年第6期36卷 385-389页

作者： Hu TAO1, Da-Fu CUI1, and You-Shang ZHANG1,2. 1Institute of Biochemistry and Cell Biology, shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Graduate School of the Chinese Academy of Sciences, shanghai 2.0031, {2. Institute of Protein Research, tongji university, shanghai 2.0031, {2. Institute of Biochemistry and Cell Biology Shanghai Institutes for Biological Sciences Chinese Academy of Sciences Graduate School of the Chinese Academy of SciencesShanghai 200031 China Institute of Protein Research Tongji UniversityShanghai 200031 China

An aspartame analogue, L-asparaginyl L-3-phenyllactic acid methyl ester was synthesized with aspartic acid replaced by asparagine and peptide bond replaced by ester bond. The aspartic acid of aspartame could be replaced by asparagine as reported in the literature. In this analogue, the hydrogen of amide group could still form a hydrogen bond with the oxygen of ester bond and the ester bond was isosteric with peptide bond. However, the product was not sweet, showing that the peptide bond could not be replaced by ester bond. The peptide C-N bond behaves as a double bond that is not free to rotate and the C, O, N and H atoms are in the same plane. The replacement of peptide bond by ester bond destroyed the unique conformation of peptide bond, resulting in the loss of sweet taste.

关键词： artificial sweetener aspartame derivative peptide bond

Stearic acid protects primary cultured cortical neurons against oxidative stress

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Acta Pharmacologica Sinica 2007年第3期28卷 315-326页

作者： Ze-jian WANG~2.Cui-ling LIANG~3 Guang-mei LI~2.Cai-yi YU~2.Ming YIN~(2.4)2.School of Pharmacy,shanghai Jiao Tong university,shanghai 2.0030,china 3 Institute of Population Studies,East china Normal university,shanghai 2.0062.china School of Pharmacy Shanghai Jiao Tong University Shanghai China Institute of Population Studies East China Normal University Shanghai China

Aim:To observe the effects of stearic acid against oxidative stress in primarycultured cortical ***:Cortical neurons were exposed to glutamate,hydrogen peroxide（H2.2.,or NaN3insult in the presence or absence of *** viability of cortical neurons was determined by MTT assay and *** antioxidant enzymes activity[superoxide dismutases（SOD）,glutathione peroxidase（GSH-Px）,and catalase（CAT）] and lipid peroxidation incultured cortical neurons were evaluated using commercial kits.{3-[l（p-chloro-benzyl）-5-（isopropyl）-3-t-butylthiondol-2.yl]-2.2.dimethylpropanoic acid,Na}[MK886;5 μmol/L;a noncompetitive inhibitor of proliferator-activated receptor（PPAR）α],bisphenol A diglycidyl ether（BADGE;100 μmol/L;an antagonist ofPPARγ）,and cycloheximide（CHX;30 μmol/L,an inhibitor of protein synthesis）were tested for their effects on the neuroprotection afforded by stearic *** blotting was used to determine the PPARγprotein level in cortical ***:Stearic acid dose-dependently protected cortical neurons againstglutamate or H2.2.injury and increased glutamate uptake in cultured *** protection was concomitant to the inhibition of lipid peroxidation and to thepromotion activity of Cu/Zn SOD and CAT in cultured cortical *** effects were completely blocked by BADGE and *** with H2.2.for 2. h,the expression of the PPARγprotein decreasedsignificantly（P2.2.n the expression of PPARγcan be attenuated by stearic ***:Stearic acid can protect corticalneurons against oxidative stress by boosting the internal antioxidant *** neuroprotective effect may be mainly mediated by the activation of PPARγandnew protein synthesis in cortical neurons.

关键词： oxidative stress receptors peroxisome prolilferator-activated neurons antioxidants

Relationship between magnetic fabric parameters and dynamic characteristics of deposits in different environments

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Chinese Science Bulletin 1998年第22期43卷 1917-1921页

作者： CHEN Qingqiang 1,3 , LI Congxian\+1 and CONG Youzi\+2.1. Marine Geology Laboratory, tongji university,{2. 2. First Institute of Oceanography, State Oceanic Administration of {2., Qingdao 2.6003, {2. 3. Guangzhou Institute of Marine Geology Laboratory Tongji University Shanghai China Guangzhou Institute of Geochemistry Chinese Academy of Sciences Guangzhou China First Institute of Oceanography State Oceanic Administration of China Qingdao China

Comparison of magnetic fabric parameters of deposits in different modern sedimentary environments indicates that values of \%P, F\% and \%L\% of eolian deposits are lower obviously than those of hydrogenic ones respectively. On relationship diagrams of magnetic fabric parameters, data points of eolian samples concentrated in limited area near origin of coordinates indicate that dynamic intensity is lower with less variation; while those of hydrogenic ones depart from origin of coordinates suggest higher intensity of sedimentary dynamics. Analyses of dynamic characteristics of different sedimentary environments indicate that values of magnetic fabric parameters of deposits are determined by dynamic types and characteristics of depositional processes. Magnetic fabric analyses of deposits are effective in determination of sedimentary environments.

关键词： magnetic fabric parameters sedimentary environment transporting medium.

Inhibitory Effect of CT12.B,an Alternative Splice Variant of CT12.A,on Lung Cancer Cell Growth

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Acta Biochimica et Biophysica Sinica 2005年第9期37卷 588-592页

作者： Dong-Ning PAN~(1,2. Jin-Jun LI~(2.3) Lin WEI~2.Ming YAO~(2.3) Da-Fang WAN~(2.3*) Jian-Ren GU~(1,2.3*) 1 shanghai Medical College,Fudan university,shanghai 2.0032.china 2.National Laboratory for Oncogenes and Related Genes,shanghai Cancer Institute,shanghai 2.0032.china 3 Medical School of shanghai Jiaotong university,shanghai 2.0032.china shanghai Medical College Fudan UniversityShanghai 200032 China National Laboratory for Oncogenes and Related Genes Shanghai Cancer InstituteShanghai 200032 China Medical School of shanghai Jiaotong universityshanghai 2.0032 China

The expression product of ct12.a,a novel gene isolated from human chromosome 17p13.3in our laboratory,was predicted to have seven transmembrane domains and could cause malignanttransformation of mouse NIH3T3 *** existed an mRNA splicing variant of ct12.a,namely ct12.b,which had a 96-nucleotide deletion and produced an in-frame loss of 32.amino acids from codon 136 tocodon 167 of *** CT12.B protein was predicted to have six transmembrane *** thisstudy,we observed that the green fluorescent protein-tagged CT12.B was localized on plasma membraneand in cytoplasm in SPC-A-1 *** expression of CT12.B/A in normal lung tissue and in lung cancercells was also *** showed that the stable CT12.B overexpression in SPC-A-1 cells resultedin a reduction of cell growth rate,and inhibited tumorigenecity and anchorage-independent growth in *** functions of CT12.A and CT12.B for cell growth appeared *** suggested that thedelayed G1/S phase transition might contribute to the inhibitory activities of CT12.B on cell growth and thatthe deleted 32.amino acids missing in CT12.B might be essential for the oncogenetic activities of CT12.A.

关键词： CT12.B alternative splicing cell growth lung cancer

Local connectivity of Julia sets for a family of biquadratic polynomials

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Science china Mathematics 2007年第10期50卷 1477-1492页

作者： Jing L~(1+) Wei-yuan QIU~2.~1 Department of Basic Education,shanghai Maritime {2.,shanghai 2.0000,china ~2.Department of Mathematics,Fudan {2.,shanghai 2.0433,china Department of Basic Education Shanghai Maritime University Shanghai China Department of Mathematics Fudan University Shanghai China

The local connectivity of Julia sets for the family of biquadratic polynomials f_c(z)= (z^2.2.^2.z^2.with a parameter c is *** is proved that for any parameter c,the boundary of the immediately attracting domain of f_... 详细信息

关键词： biquadratic polynomials Julia sets local connectivity