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SHEsis,a powerful software platform for analyses of linkage disequilibrium,haplotype construction,and genetic association at polymorphism loci

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Cell Research 2005年第2期15卷 97-98页

作者： Yong Yong SHI1,2. Lin HE2.3,*1Bio-X Life Science Research Center, {2. Jiao Tong university, {2., china 2.nstitute for Nutritional Sciences, {2. Institute of Biological Sciences, Chinese Academy of Sciences, {2.,china 3NHGG, Bio-X Center, {2. Jiao Tong university, {2., china Bio-X Life Science Research Center Shanghai Jiao Tong University Shanghai China Institute for Nutritional Sciences Shanghai Institute of Biological Sciences Chinese Academy of Sciences Shanghai China NHGG Bio-X Center Shanghai Jiao Tong University Shanghai China

In multiloci-based genetic association studies of complex diseases, a powerful and high efficient tool for analyses oflinkage disequilibrium (LD) between markers, haplotype distributions and many chi-square/p values with a large numberof samples has been sought for long. In order to achieve the goal of obtaining meaningful results directly from raw data,we developed a robust and user-friendly software platform with a series of tools for analysis in association study withhigh efficiency. The platform has been well evaluated by several sets of real data.

关键词： software linkage disequilibrium haplotype analysis genetic association study.

Effect of Curing Regime on Bonding Strength of EVA Modified Mortar to Tile

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Journal of Wuhan university of Technology(Materials Science) 2010年第2期25卷 346-348页

作者：何代华 School of Materials Science & Engineering University of Shanghai for Science Technology Key Laboratory of Advanced Civil Engineering Materials Ministry of Education Tongji University

Ethylene-Vinyl Acetate （EVA） redispersible powder and latex were used to modify mortar. Three kinds of curing regimes： standard curing, high temperature curing and freeze-thaw circle curing were adopted to cure the bonded samples. Bonding strength of EVA modified mortar was tested at 2. days. The development of bonding strengths under all three curing regimes were discussed and compared. The experimental results show that bonding strength increases with the increase of EVA content in mortar. The curing regime used within 2. days is critical according to the bonding strengths values under three curing regimes for different ages. The reasons of that the EVA can improve the bonding strength were analyzed.

关键词： EVA redispersible powder latex bonding strength curing regime

Mechanical Properties of Asphalt Pavement Structure in Highway Tunnel

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Journal of shanghai Jiaotong university(Science) 2008年第2期13卷 206-210页

作者：石春香郭忠印 shanghai Institute of Technology tongji university

A linear full 3D finite element method (FEM) was performed in order to present the key design parameters of highway tunnel asphalt pavement under double-wheel load on rectangular loaded area considering horizontal contact stress induced by the acceleration/deceleration of *** key design parameters are the maximum horizontal tensile stresses at the surface of the asphalt layer,the maximum horizontal tensile stresses at the bottom of the asphalt layer and the maximum vertical shear stresses at the surface of the as- phalt layer were *** influencing factors such as double-wheel weight;asphalt layer thickness;base course stiffness modulus and thickness;and the contact conditions among the structure layers on these key design parameters were also examined separately to propose construction procedures of highway tunnel asphalt pavement.

关键词： tunnel asphalt pavement structure three-dimensional finite element method horizontal force horizontal tensile stress vertical shear stress

Efficient video cutout based on adaptive multilevel banded method

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Science china(Information Sciences) 2012年第5期55卷 1082-1092页

作者： CHEN MinGang 1,SUI BoCong 1,GAO Yan 2.& MA LiZhuang 1 1 Department of Computer Science and Engineering,shanghai Jiao Tong {2.,shanghai 2.02.0,china 2.Software Engineering Institute,East china Normal {2.,shanghai 2.0062.china Department of Computer Science and Engineering Shanghai Jiao Tong University Shanghai China Software Engineering Institute East China Normal University Shanghai China

Although many efficient image cutout approaches have been proposed,it is still a challenge to cut out foreground objects from a video clip because of the costs of time and memory consumption and the difficulty in maintaining temporal coherence for the cutout *** this paper,we propose a novel and efficient video cutout approach by extending a multilevel banded image segmentation method to video *** our method,the segmentation results are propagated frame by frame at the lowest resolution level based on optical flow,and are refined in image pyramids level by level through banded graph *** construct an adaptive narrow band to ensure that the segmentation result falls exactly into the narrow band during *** results show that the video cutout approach based on adaptive multilevel bands dramatically reduces time and memory costs,and achieves ideal segmentation results.

关键词： video object cutout multilevel band graph cuts video segmentation

Local well-posedness of lower regularity solutions for the incompressible viscoelastic fluid system

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Science china Mathematics 2010年第6期53卷 1521-1530页

作者： ZHAO WenJing1,& DU DaPeng2.1School of Mathematics Science,Fudan university,{2. 2.0433,{2. 2.nstitution of Mathematics,Fudan university,{2. 2.0433,{2. School of Mathematics Science Fudan University Shanghai China Institution of Mathematics Fudan University Shanghai China

In the present paper,the local well-posedness of the incompressible viscoelastic fluid system in the whole space is proved under the following assumption on the initial data:the deformation tensor is Hlder continuou... 详细信息

关键词： Oldroyd-B model characteristic direction Stokes kernel

Transient species and its properties of melatonin

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Science china Chemistry 2006年第4期49卷 308-314页

作者： ZHU Hongping1,2. ZHANG Zhaoxia1,2. ZHAO Hongwei1, WANG Wenfeng1 & YAO Side1 1. {2. Institute of Applied Physics, Chinese Academy of Sciences, {2. 2.1800, {2. 2. Graduate university of the Chinese Academy of Sciences, Beijing 100049, {2. shanghai Institute of Applied Physics Chinese Academy of Sciences Shanghai China Graduate university of the Chinese Academy of Sciences Beijing China

The photo-physical and photo-chemical properties of melatonin (ML) werestudied by 2.6 nm laser flash photolysis (LFP). ML undergoes photo-ionization to produce radicalcation of ML (ML^(·+))and hydrated electrons (e_(aq)^-), while excited triplet state ~3ML~* is alsoformed during photolysis. The oxidation via one electron transfer from ML to SO_4^(·+) and thetriplet state of riboflavin (~3RF~*) has been also investigated and the rate constants for theprocess have been determined to be 8.0x10^9 and 1.4x10^9 L·mol^(-1)·s^(-1) respectively. Theradical cation of 2.2.'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid)(ABTS^(·+)) scavengingcapacities of melatonin and other antioxidants are compared in this paper.

关键词： melatonin, laser flash photolysis, photoionization, triplet state.

On the Cayley-Bacharach property and the construction of vector bundles

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Science china Mathematics 2011年第9期54卷 1891-1898页

作者： SUN Hao 1,2.1 Department of Mathematics and Statistics,Huazhong Normal university,Wuhan 430079,{2. 2.Department of Mathematics,East {2. Normal university,shanghai 2.02.1,{2. Department of Mathematics and Statistics Huazhong Normal University Wuhan China Department of Mathematics East China Normal University Shanghai China

We study the Cayley-Bacharach property on complex projective smooth varieties of dimension n≥2.for zero dimensional subscheme defined by the zero set of the wedge of r-n + 1 global sections of a rank r≥n vector bund... 详细信息

关键词： Cayley-Bacharach property vector bundle reflexive sheaf k-very ample

Excavation and characterization of refuse in closed landfill

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Journal of Environmental Sciences 2002年第3期14卷 303-308页

作者： ZHAO You cai (The State Key Laboratory of Pollution Control and Resource Reuse, School of Environmental Science and Engineering, tongji university, shanghai 2.0092. china. ) The State Key Laboratory of Pollution Control and Resource Reuse School of Environmental Science and EngineeringTongji UniversityShanghai 200092China E-mail:zyclmk @ online***

Refuse in landfills becomes stabilized as organic matter in refuse degrades and soluble inorganic substances dissolve during their long term stabilization process. In this paper, this process is also referred to as mineralization process and the resultant stabilized refuse referred to as aged refuse. Aged refuse contains a wide spectrum and huge quantity of microorganisms with strong decomposition capability for refractory organic matter present in some wastewater such as leachate. In this study, aged refuse excavated from 2.to 10 years old closed landfill compartments in shanghai Refuse Landfill is characterized in terms of particulate distribution by screening, total nitrogen, total phosphorus, biodegradable matter. The approaches for redevelopment of both land and aged refuse in the stabilized landfills are proposed.

关键词： landfill refuse mineralization

Autoantibody against Cardiac β1-Adrenoceptor Induces Apoptosis in Cultured Neonatal Rat Cardiomyocytes

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Acta Biochimica et Biophysica Sinica 2006年第7期38卷 443-449页

作者： Yan GAO~1 Hui-Rong LIU~1 Rong-Rui ZHAO~1 Jian-Ming ZHI~(2.) 1 Department of Cardiovascular Physiology Shanxi Medical university,Taiyuan 030001,{2. 2.Department of Physiology,{2. Jiaotong university,College of Basic Medicine,{2. 2.002.,{2. Department of Cardiovascular Physiology Shanxi Medical UniversityTaiyuan 030001 China Department of Physiology Shanghai Jiaotong University College of Basic MedicineShanghai 200025 China

To clarify whether apoptosis is involved in the injury processes induced by autoantibodyagainst cardiac β1-adrenoceptor,we investigated the biological and apoptotic effects of antibodies on culturedneonatal rat *** rats were immunized with peptides corresponding to the second extra-cellular loop of the β1-adrenoceptor to induce the production of anti-β1-adrenoceptor antibodies in the ***（Ig）G in the sera was detected using synthetic antigen enzyme-linked immunosorbentassay and purified using the diethylaminoethyl cellulose ion exchange *** of cardiomyo-cytes was evaluated using agarose gel electrophoresis and flow *** results showed that thepositive serum IgG greatly increased the beating rates of cardiomyocytes and showed an"agonist-like"***,positive serum IgG induced cardiomyocyte apoptosis after treatment with β1-adrenoceptor overstimulation for *** effects of monoclonal antibody against β-adrenoceptor werealso found to be similar to those of positive serum *** was suggested that the autoantibody could inducecardiomyocyte apoptosis by excessive stimulation of β1-adrenoceptor.

关键词： β1-adrenoceptor rat cardiomyocyte autoantibody apoptosis