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A novel fabrication technique for three-dimensional concave nanolens arrays

Journal of materiomics 2020年第3期6卷 557-562页

作者： Tianli Duan Kang Xu Zhihong Liu Chenjie Gu Jisheng Pan Diing Shenp ang Rui Zhang Yao Wang Xuhang ma SUSTech Core Research Facilities Southern University of Science and Technology1088 Xueyuan AvenueShenzhen518055China Department of Mechanical and Energy Engineering Southern University of Science and Technology1088 Xueyuan AvenueShenzhen518055China School of Microelectronics Xidian UniversityXian710071China Institute of Photonics Ningbo University818 Feng Hua RoadNingbo315211China Institute of materials Research and Engineering A*STAR(Agency for ScienceTechnology and Research)2 Fusionopolis WayInnovis#08-03138634Singapore School of Electrical and Electronic Engineering Nanyang Technological UniversityNanyang Avenue639798Singapore

A novel facile technique is proposed for fabricating three-dimensional(3D)concave nanolens arrays on a silicon *** technique leverages an inherent characteristic of the polymethyl methacrylate(PMma)resist during inductively coupled plasma(ICP)*** tendency for plasma ions to accumulate at the edge of the PMma resist helps create a local electric field that causes the ions to etch the sidewall of the PMma *** process progressively increases the uncovered area,resulting in a graded etched depth or a concave structure in the *** addition,using a given ICP etching recipe,the time required for a PMma resist to be removed by sidewall etching is determined by its *** use of PMma resist of different widths enables one to achieve structures of varying etched depths and thus a 3D lens *** characteristics of the fabricated nanolens were simulated using the FDTD(Finite-difference time-domain)method,and focal lengths ranging from 150 nm to 420 nm were *** type of nanolens is very useful in ultraviolet optical devices and CMOS image sensors.

关键词： Concave nanolens Three-dimensional lens array Nanofabrication Polymethyl methacrylate(PMma) Inductively coupled plasma(ICP)

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Lower Bifidobacteria counts in both duodenal mucosa-associated and fecal microbiota in irritable bowel syndrome patients

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World Journal of Gastroenterology 2009年第23期15卷 2887-2892页

作者： angèle PM Kerckhoffs Melvin Samsom Michel E van der Rest Joris de Vogel Jan Knol Kaouther Ben-Amor Louis ma Akkermans Gastrointestinal Research Unit Department of Gastroenterology and Surgery University Medical Center Utrecht Heidelberglaan 100 F02.618 3584CX Utrecht The Netherlands BioVisible BV LJ Zielstraweg 1 9713 GX Groningen The Netherlands Danone Research-Centre for Specialized Nutrition Bosrandweg 20 6704PH Wageningen The Netherlands

AIM: To determine the composition of both fecal and duodenal mucosa-associated microbiota in irritable bowel syndrome (IBS) patients and healthy subjects using molecular-based techniques. METHODS: Fecal and duodenal mucosa brush samples were obtained from 41 IBS patients and 26 healthy subjects. Fecal samples were analyzed for the composition of the total microbiota using fluorescent in situ hybridization (FISH) and both fecal and duodenal brush samples were analyzed for the composition of bif idobacteria using real-time polymerase chain reaction. RESULTS: The FISH analysis of fecal samples revealed a 2-fold decrease in the level of bifidobacteria (4.2 ± 1.3 vs 8.3 ± 1.9, P 1) in IBS patients compared to healthy subjects, whereas no major differences in other bacterial groups were observed. At the species level, Bifidobacterium catenulatum levels were significantly lower (6 ± 0.6 vs 19 ± 2.5, P 1) in the IBS patients in both fecal and duodenal brush samples than in healthy ***: Decreased bifidobacteria levels in both fecal and duodenal brush samples of IBS patients compared to healthy subjects indicate a role for microbiotic composition in IBS pathophysiology.

关键词： Irritable bowel syndrome Gut microbiota Bifidobacteria Bifidobacterium catenulatum

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pH-responsive Micelles from a Blend of PEG-b-PLA and PLA-b-PDPA Block Copolymers: Core Protection Against Enzymatic Degradation

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Chinese Journal of Polymer Science 2018年第11期36卷 1262-1268页

作者： Yan-Ling Xu Ao-Ting Qu Ru-Jiang ma ang Li Zhen-Kun Zhang Zhi-Qiang Shang Yao-Fang Zhang Lu-Xia Bu Ying-Li An State Key Laboratory of Medicinal Chemical Biology Key Laboratory of Functional Polymer Materials of Ministry of Education Institute of Polymer Chemistry Nankai University College of Basic Science Chemistry Experiment Teaching Center Tianjin Agricultural University

pH-responsive micelles with a biodegradable PLA core and a mixed PEG/PDPA shell were prepared by self-assembly of poly（ethylene glycol）-b-poly（lactic acid）（PEG-b-PLA） and poly（2-（diisopropylamino）ethyl methacrylate）-b-poly（lactic acid）（PDPA-b- PLA）. The micellization status with different pH and the enzyme degradation behavior were characterized by IH-NMR spectroscopy, dynamic light scattering measurement and zeta potential test. The pH turning point of PDPA block was determined to be in the range of 5.5-7.0. While the pH was above 7.0, the PDPA block collapsed onto the PLA core and could protect the PLA core from invasion of enzyme, as a result, the micelle exhibited a resistance to the enzymatic degradation.

关键词： pH-responsive Enzymatic degradation Poly(lactic acid)

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An adhesive and resilient hydrogel for the sealing and treatment of gastric perforation

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Bioactive materials 2022年第8期7卷 52-60页

作者： Jing Chen Julia S.Caserto Ida ang Kaavian Shariati James Webb Bo Wang Xi Wang Nikolaos Bouklas Minglin ma College of Pharmacy Nanjing University of Chinese MedicineNanjing210023China Department of Biological and Environmental Engineering Cornell UniversityIthacaNY14853USA Robert Frederick Smith School of Chemical and Biomolecular Engineering Cornell UniversityIthacaNY14853USA Sibley School of Mechanical and Aerospace Engineering Cornell UniversityIthacaNY14853USA

Adhesive hydrogels have been recently proposed as a potential option to seal and treat gastric perforation(GP)which causes high mortality despite advancements in surgical ***,to be effective,the hydrogels must have sufficient tissue adhesiveness,tough mechanical property,tunable biodegradability and ideally are easy to apply and ***,we report an adhesive and resilient hydrogel for the sealing and treatment of gastric *** hydrogel consists of a bioactive,transglutaminase(TG)-crosslinked gelatin network and a dynamic,borate-crosslinked poly-N-[Tris(hydroxymethyl)methyl]acrylamide(PTH)*** hydrogel can be formed in situ,facilitating easy delivery to the GP and allowing for precise sealing of the *** vivo experiments,using a perforated stomach mouse model,shows that the adhesive hydrogel plug effectively seals GP defects and promotes gastric mucosa ***,this hydrogel represents a promising biomaterial for GP treatment.

关键词： Adhesive hydrogel plug Gastric perforation Thermo-responsive Regeneration

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Comparative study on characteristics of Si-based AlGaN/GaN recessed MIS-HEMTs with HfO2 and Al2O3 gate insulators

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Chinese Physics B 2020年第8期29卷 445-450页

作者： Yao-Peng Zhao Chong Wang Xue-Feng Zheng Xiao-Hua ma Kai Liu ang Li Yun-Long He Yue Hao Key Laboratory of Wide Band-Gap Semiconductor materials and Devices School of MicroelectronicsXidian UniversityXi'an 710071China

Two types of enhancement-mode(E-mode)AlGaN/GaN metal-insulator-semiconductor high-electron-mobility transistors(MIS-HEMTs)with different gate insulators are fabricated on Si *** HfO2 gate insulator and the Al2O3 gate insulator each with a thickness of 30 nm are grown by the plasma-enhanced atomic layer deposition(PEALD).The energy band diagrams of two types of dielectric MIS-HEMTs are *** breakdown voltage(VBR)of HfO2 dielectric layer and Al2O3 dielectric layer are 9.4 V and 15.9 V,*** the same barrier thickness,the transconductance of MIS-HEMT with HfO2 is *** threshold voltage(Vth)of the HfO2 and Al2O3 MIS-HEMT are 2.0 V and 2.4 V,respectively,when the barrier layer thickness is 0 *** C-V characteristics are in good agreement with the Vth's transfer *** the barrier layer becomes thinner,the drain current density decreases *** to the dielectric/AlGaN interface is very close to the channel,the scattering of interface states will lead the electron mobility to *** current collapse and the Ron of Al2O3 MIS-HEMT are smaller at the maximum gate *** Al2O3 has excellent thermal stability and chemical stability,the interface state density of Al2O3/AlGaN is less than that of HfO2/AlGaN.

关键词： AlGaN/GaN enhancement-mode MIS-HEMT HfO2 Al2O3

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Dissociation of gas hydrates by hydrocarbon migration and accumulation-derived slope failures:An example from the South China Sea

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Geoscience Frontiers 2022年第2期13卷 295-310页

作者： Zhi-Feng Wan Wei Zhang Chong ma Jin-Qiang Liang ang Li Da-Jiang Meng Wei Huang Cheng-Zhi Yang Jin-Feng Zhang Yue-Feng Sun School of marine Sciences Sun Yat-sen UniversityZhuhai 519082China Gas Hydrate Engineering Technology Center Guangzhou Marine Geological SurveyChina Geological SurveyMinistry of Natural ResourcesGuangzhou 510075China Southern marine Science and Engineering Guangdong Laboratory(Zhuhai) Zhuhai 519082China School of mathematics and Physics China University of Geosciences(Wuhan)Wuhan 430074China Qingdao Institute of marine Geology Qingdao 266071China Department of Geology&Geophysics Texas A&M UniversityCollege Station 77843-3115United States

The mechanism of slope failure associated with overpressure that is caused by hydrocarbon migration and accumulation remains ***-resolution seismic data and gas hydrate drilling data collected from the Shenhu gas hydrate field(site SH5)offer a valuable opportunity to study the relations between submarine slope failure and hydrocarbon accumulation and flow that is associated with a~2 kmdiameter gas chimney developed beneath site SH5 where none gas hydrates had been recovered by drilling and sampling despite the presence of distinct bottom simulating reflectors(BSRs)and favorable gas hydrate *** mechanism of submarine slope failure resulted from buoyancy extrusion and seepage-derived deformation which were caused by overpressure from a~1100 m-high gas column in a gas chimney was studied via numerical ***~9.55 MPa overpressure caused by hydrocarbons that migrated through the gas chimney and then accumulated beneath subsurface gas hydratebearing impermeable *** may have resulted in a submarine slope failure,which disequilibrated the gas hydrate-bearing zone and completely decomposed the gas hydrate once precipitated at site *** the gas hydrate decomposition,the largely impermeable sediments overlying the gas chimney may have undergone a major upward deformation due to the buoyancy extrusion of the overpressure in the gas chimney,and slope failure was initiated from plastic strain of the sediments and reduced internal *** failure subsequently resulted in partial gas hydrate decomposition and sediment permeability *** pressurized gas in the gas chimney may have diffused into the overlying sediments controlled by seepage-derived deformation,causing an effective stress reduction at the base of the sediments and significant plastic *** may have formed a new cycle of submarine slope failure and finally the total gas hydrate *** modeling results of buoyancy extrusion and seepage-deri

关键词： Natural gas hydrate Submarine slope failure Gas chimney Buoyancy extrusion Seepage-derived deformation Shenhu area Northern South China Sea

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香菇杂交菌株抗木霉能力筛选及可靠性分析

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中国食用菌 2024年第2期43卷 76-81页

作者：张根伟王雅囡王晓颖刘振国马宏刘昆昂河北省科学院生物研究所河北石家庄050081

香菇育种中,抗木霉能力是筛选优良菌株的重要指标。为了提高菌株抗木霉能力筛选效率,通过香菇与木霉菌株在培养皿中的对峙培养,利用拮抗带宽度、香菇拮抗半径和木霉入侵距离3种方法对256株香菇杂交菌株进行抗木霉能力筛选。每种方法各筛... 详细信息

香菇育种中,抗木霉能力是筛选优良菌株的重要指标。为了提高菌株抗木霉能力筛选效率,通过香菇与木霉菌株在培养皿中的对峙培养,利用拮抗带宽度、香菇拮抗半径和木霉入侵距离3种方法对256株香菇杂交菌株进行抗木霉能力筛选。每种方法各筛选61株抗性强的菌株(合计101株)进行栽培试验,比较抗木霉能力的一致性、相关性和可靠性。结果表明,香菇拮抗半径、拮抗带宽度和木霉入侵距离3种方法测定的菌株抗木霉能力趋势线一致,相关系数分别为-0.699、0.536和-0.675,存在极显著较大相关,栽培污染群体指数分别为6.3、4.6和9.9,说明拮抗带宽度测定方法筛选的菌株抗木霉能力更强,其次为香菇拮抗半径,最差为木霉入侵距离。

关键词：香菇菌株抗木霉拮抗带宽度香菇拮抗半径木霉入侵距离

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镍钴水滑石纳米笼/GO复合材料在锂离子电池负极中的应用

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高师理科学刊 2024年第1期44卷 43-50,77页

作者：高昂周胜冯立峰张强哈尔滨师范大学物理与电子工程学院黑龙江哈尔滨150025

近年来,水滑石(LDH)材料因其组成、结构和形貌易于调节,具有丰富的活性位点,被认为是高性能锂离子电池(LIBs)负极的替代材料,然而水滑石作为负极仍存在电导率差和结构易聚集等问题.于此同时,金属有机框架(MOFs)及碳基材料也由于其优秀... 详细信息

近年来,水滑石(LDH)材料因其组成、结构和形貌易于调节,具有丰富的活性位点,被认为是高性能锂离子电池(LIBs)负极的替代材料,然而水滑石作为负极仍存在电导率差和结构易聚集等问题.于此同时,金属有机框架(MOFs)及碳基材料也由于其优秀的孔隙率、比表面积以及良好的电导率在储能领域得到了广泛的关注.考虑到这二者有望对LDH的主要缺陷有所改进,提出了将原位沉淀、化学刻蚀法和静电吸附法相结合,使镍钴水滑石纳米笼(H-(Ni,Co)-LDHP)能够固定在GO上,从而得到镍钴水滑石纳米笼/氧化石墨烯复合材料(H-(Ni,Co)-LDHP/GO).这种GO上密集分布的中空纳米结构更能有效抑制水滑石纳米片的聚集,并有利于锂离子的脱嵌.H-(Ni,Co)-LDHP/GO纳米复合材料作为锂离子电池的负极,在电流密度为50m A·g^(-1)下,循环第一圈库伦效率可达68%,循环50圈后电容保留率为68.4%.

关键词：锂离子电池水滑石负极材料

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Multi-affine registration using local polynomial expansion

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Journal of Zhejiang University-Science C(Computers and Electronics) 2010年第7期11卷 495-503页

作者： Yuan-jun W'ang Guimar FARNEBACK Carl-Fredrik WESTIN Digital Medical Research Center Shanghai Medical School Fudan University Shanghai 200032 China Lab of mathematics in Imaging Brigham and Women's Hospital Harvard Medical School Boston 02115 MA USA

In this paper, we present a non-linear (multi-affine) registration algorithm based on a local polynomial expansion model. We generalize previous work using a quadratic polynomial expansion model. Local affine models are estimated using this generalized model analytically and iteratively, and combined to a deformable registration algorithm. Experiments show that the affine parameter calculations derived from this quadratic model are more accurate than using a linear model. Experiments further indicate that the multi-affine deformable registration method can handle complex non-linear deformation fields necessary for deformable registration, and a faster convergent rate is verified from our comparison experiment.

关键词： Deformable registration Polynomial expansion Least squares Multi-affine Normalized convolution

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Pulse oximeter as a home assessment tool:Knowledge and user experience among the community in malaysia during the COVID-19 pandemic

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Asian Pacific Journal of Tropical Medicine 2022年第5期15卷 213-219页

作者： Siew-Keah Lee Jin Wei ma Khai Ying Chan Yi Song Cheong Wan Ting Hong Regine Chew Yi Ong Wei Cheng Tay ang-Lim Chua Faculty of Medicine and Health Sciences Universiti Tunku Abdul RahmanMalaysia Faculty of Medicine Universiti Teknologi MARAMalaysia

Objective:To determine the degree of knowledge in the usage of pulse oximeter as a home assessment tool among the community in ***:A cross-sectional survey was conducted in November *** questionnaire assessed the knowledge in using pulse oximeters,user experience and opinions in using pulse oximeter as a home assessment tool during the ***:A total of 504 respondents were included in the study,and the mean score in knowledge related to application of pulse oximetry was 73.00%,while the mean score in knowledge related to factors affecting pulse oximetry readings was only 38.51%.A total of 90.5% of the respondents recognised normal pulse rate and 88.5% knew the blood oxygen saturation levels of a healthy adult,while 69.4% recognised the definition of silent *** addition,the majority of the respondents agreed that factors such as poor blood circulation(71.2%),excessive movements(69.8%),and hand position(60.7%)affected oximetry ***,61.7%,81.7%,77.2% and 76.8% of the respondents could not identify nail polish,skin colour,skin thickness and tattoos as factors that may affect oximetry readings ***:The respondents showed a satisfactory level of knowledge related to application of pulse oximetry,but a poor level of knowledge related to factors affecting pulse oximetry readings among the community in *** efforts in educating the community on the correct use of pulse oximeters are crucial for appropriate home assessment and avoiding unnecessary stress.

关键词： COVID-19 Pulse oximetry SpO2 Home assessment tool Silent hypoxia

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