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亚洲精细农业与计算机农业应用联合大会

作者： LIU lu 1.ZHANG Jian 2 FU Zetian 1.1. College of Engineering China Agricultural University Beijing 1.0083 China 2. School of Economic Management Beijing In formation Technology University Bei jing 1.01.2 China

The most important aspect of fish spoilage is the effective monitoring and analyzing of the time-temperature condit ions during the cold chain, which affect both the safety and quality of fish. The time-temperature data is usually recorded by TTIs, TTE, and other indicators at very independent part of the cold chain, and stored in the database according to the cold chain management system. As the data files get increasingly large, the identification of the stage at the cold chain is immethodical to be classified automatically by time -temperature data. To realize the activity of the procedurals during the chain, the attributive time-temperature data files should be clearly presented and be sorted automatically in the database. In this paper, techniques of data fusion, data mining and their integration are used to recognize and classify the files corresponding with the processes during the cold chain intellect ively. Firstly, the constitution and common time-temperature data collection technique of the cold chain are analyzed. A framework of t ime -temperature data collection system is proposed by time-temperature indicators in conformity to the phases of the chain. The deposition of the indicator is also presented to get the time-temperature data at transportation. Secondly, data min ing is used to identify the character of time-temperature files. Rough Set theory, a tool of data min ing is imported to establishment of in formation expression system, to d ispersion and reduction of decision table. The creation of decision rules are elaborated by the algorithm. In this part, data mining is aiming for getting the rules induction fro m representative time-temperature file samples during the cold chain. Thirdly, data fusion theory is presented to automatically classify and storage on utilizing the rules founded. By using the classificat ion rules fro m data mining, data fusion ensures the now data collected by time-temperature indicators could be automatically sorted in

关键词： cold chain rough set data min ing data fusion time-temperature files

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辨析滞脉源流

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中华中医药杂志 2024年第7期39卷 3297-3300页

作者：甄林强庞雨赵璐邱帆河南中医药大学郑州450008 河南中医药大学第三附属医院郑州450003

滞脉源于古代典籍医案,未得脉学专著正名,于近代被正式提出。文章结合古代医籍记载及近代医家阐述,追溯滞脉的历史渊源、辨析滞脉的脉象特征、探究滞脉的临床意义,并对滞脉的形成机制进行讨论,为滞脉的标准化研究做出探索,初步得出以下... 详细信息

滞脉源于古代典籍医案,未得脉学专著正名,于近代被正式提出。文章结合古代医籍记载及近代医家阐述,追溯滞脉的历史渊源、辨析滞脉的脉象特征、探究滞脉的临床意义,并对滞脉的形成机制进行讨论,为滞脉的标准化研究做出探索,初步得出以下结论:滞脉的脉象特征即中取可应,按之方得,脉幅较小,脉管欠柔和,来去之势有黏滞、不畅快之感,至数多无异常;滞脉对提示诸病邪气导致的气机郁滞具有特异性诊断价值,值得学习研究;滞脉脉理的完善对当代中医脉学的发展有着特殊意义。

关键词：滞脉脉象特征临床意义中医脉学气机郁滞诊断

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Weak Continuity and Compactness for Nonlinear Partial Differential Equations

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Chinese Annals of Mathematics,Series B 2015年第5期36卷 715-736页

作者： Gui-qiang G.CHEN School of Mathematical Sciences Fudan University Academy of Mathematics and Systems Science Chinese Academy of Sciences Mathematical Institute University of Oxford

This paper presents several examples of fundamental problems involving weak continuity and compactness for nonlinear partial differential equations, in which compensated compactness and related ideas have played a significant role. The compactness and convergence of vanishing viscosity solutions for nonlinear hyperbolic conservation laws are first analyzed, including the inviscid limit from the Navier-Stokes equations to the Euler equations for homentropic flow, the vanishing viscosity method to construct the global spherically symmetric solutions to the multidimensional compressible Euler equations, and the sonic-subsonic limit of solutions of the full Euler equations for multi-dimensional steady compressible fluids. Then the weak continuity and rigidity of the Gauss-Codazzi-Ricci system and corresponding isometric embeddings in differential geometry are revealed. Further references are also provided for some recent developments on the weak continuity and compactness for nonlinear partial differential equations.

关键词： Weak continuity Compensated compactness Nonlinear partial differential equations Euler equations Gauss-Codazzi-Ricci system

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Molecular cloning, pathologically-correlated expression and functional characterization of the colony- stimulating factor 1.receptor （CSF-1.） gene from a teleost, Plecoglossus altivelis

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Zoological Research 2016年第2期37卷 96-102页

作者： qiang CHEN Xin-Jiang lu Ming-Yun LI Jiong CHEN Laboratory of Biochemistry and Molecular Biology School of Madne Sciences Ningbo University Ningbo 315211 China Collaborative Innovation Center for Zhejiang Marine High-efficiency and Healthy Aquaculture Ningbo University Ningbo 315211 China

Colony-stimulating factor 1.receptor （CSF-1.） is an important regulator of monocytes/macrophages （MO/MФ）. Although several CSF-1. genes have been identified in teleosts, the precise role of CSF- 1. in ayu （Plecoglossus altivelis） remains unclear. In this study, we characterized the CSF-1. homologue from P. altivelis, and named it PaCSF-1.. Multiple sequence alignment and phylogenetic tree analysis showed that PaCSF-1. was most closely related to that of Japanese ricefish （Oryzias latipes）. Tissue distribution and expression analysis showed that the PaCSF-1. transcript was mainly expressed in the head kidney-derived MO/MФ, spleen, and head kidney, and its expression was significantly altered in various tissues upon Vibrio anguillarum infection. After PaCSF-1. neutralization for 48 h, the phagocytic activity of MO/MФ was significantly decreased, suggesting that PaCSF-1. plays a role in regulating the phagocytic function of ayu MO/M（P.

关键词： Colony-stimulating factor 1.receptor Pathologically-correlated expression Monocytes/macrophages Phagocytosis Sequence analysis

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结构相变引起单层RuSe_(2)载流子迁移率的提高

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物理学报 2024年第14期73卷 177-184页

作者：陆康俊王一帆夏谦张贵涛陈乾东南大学物理学院量子材料与信息器件教育部重点实验室南京211189

过渡金属二硫族化合物(TMDs)是二维材料家族中的重要成员,具有丰富多样的晶体结构和物理特性,是近年来在科学研究和器件应用领域关注度较高的材料之一.本文通过第一性原理计算研究了单层RuSe_(2)的结构和相变,在确定其基态为二聚相(T′... 详细信息

过渡金属二硫族化合物(TMDs)是二维材料家族中的重要成员,具有丰富多样的晶体结构和物理特性,是近年来在科学研究和器件应用领域关注度较高的材料之一.本文通过第一性原理计算研究了单层RuSe_(2)的结构和相变,在确定其基态为二聚相(T′相)的同时,发现该材料存在能量相近的三聚相(T′″相).分别从动力学和热力学角度预测了该晶相结构的稳定性.结合相变势垒的计算和分子动力学模拟,预测在室温下对相结构施加较小的应力就可以实现晶格从T′相到T′″相的转变.相变后的能带结构以及载流子迁移率都发生了明显的改变,其带隙由1.1. eV的间接带隙转变为0.71.eV的直接带隙,载流子迁移率有了大幅的提升,空穴迁移率达到了3.22×1.^(3)cm^(2)·V^(-1.·s^(-1..本文对比研究了RuSe_(2)单层中可能共存的两种畸变相,分析了不同晶相的电子结构和迁移率,为实验上研究二维RuSe_(2)材料及其在未来器件中的应用提供了理论依据.

关键词：二硒化钌结构相变载流子迁移率第一性原理计算

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Steroids hydroxylation catalyzed by the monooxygenase mutant 1.9-3 from Bacillus megaterium BM3

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Acta Pharmaceutica Sinica B 2017年第4期7卷 510-516页

作者： Xing Liu Jian-qiang Kong State Key Laboratory of Bioactive Substance and Function of Natural Medicines&Ministry of Health Key Laboratory of Biosynthesis of Natural Products Institute of Materia MedicaChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100050China

The search of new substrates with pharmaceutical and industrial potential for biocatalysts including cytochrome P450 enzymes is always challenging. Cytochrome P450 BM3 mutant 1.9-3, a versatile biocatalyst, exhibited hydroxylation activities towards fatty acids and alkanes. However, there were limited reports about its hydroxylation activity towards steroids. Herein, an Escherichia coli-based whole-cell extract containing the recombinant 1.9-3 protein was used as the biocatalyst to screen 1. steroids. Results revealed that 1.9-3 was able to specifically hydroxylate androstenedione (1. at 1.-position, generating a hydroxylated steroid 1.-OH-androstenedione (1.). To investigate whether C-1. hydroxylation catalyzed by BM3 mutant 1.9-3 could be industrially used, an optimization of catalyzing conditions was performed. Accordingly, the BM3 mutant 1.9-3 enzyme was observed to display maximum activity at 37 °C, under pH 7.0 for 4 h, with 37% transformation rate. Moreover, four 1.9-3 variants were generated by random mutagenesis with the aim of improving its activity and expanding substrate scope. Surprisingly, these mutants, sharing a common mutated site R379S, lost their activities towards androstenedione (1.. These data clearly indicated that arginine residue located at site 379 played key role in the hydroxylation activities of 1.9-3. Overall, these new findings broadened the substrate scope of 1.9-3 enzyme, thereby expanding its potential applications as a biocatalyst on steroids hydroxylation in pharmaceutical industry.

关键词： Cytochrome P450 BM3 1.9-3 Steroids hydroxylation 1.-OH-androstenedione Biocatalyst

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韦尼克脑病伴颅内出血和皮层受损1.并文献复习

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中国实用内科杂志 2024年第4期44卷 350-352页

作者：孙坤芦军张龙张冉丁智慧内蒙古民族大学赤峰临床医学院内蒙古自治区赤峰024000 赤峰学院附属医院神经内科内蒙古自治区赤峰024000 赤峰学院附属医院普外科内蒙古自治区赤峰024000

韦尼克脑病(Wernicke’s encephalopathy,WE)是一种继发于硫胺素(维生素B1.缺乏症所导致严重且危及生命的急性神经系统综合征[1.2]。其特征性临床表现为眼球运动障碍、共济失调、记忆与意识障碍的典型三联征,三联征只存在于1.%的WE患病... 详细信息

韦尼克脑病(Wernicke’s encephalopathy,WE)是一种继发于硫胺素(维生素B1.缺乏症所导致严重且危及生命的急性神经系统综合征[1.2]。其特征性临床表现为眼球运动障碍、共济失调、记忆与意识障碍的典型三联征,三联征只存在于1.%的WE患病群体中,大约1.%的患者在患病时没有任何经典三联征的症状之一,在这种情况下WE经常被误诊,并因此危及生命[3-4]。如果治疗不当,可能会导致严重的神经系统疾病,如科萨科夫精神病(Korsakoff psychosis)、终生残疾甚至死亡[2,5]。故对于WE准确诊断与早期治疗至关重要。

关键词：韦尼克脑病硫胺素缺乏颅内出血皮层受损恶性肿瘤

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Microwave Generation from an Oscillating Virtual Cathode Produced by Non-homogeneous Electron Beams

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Chinese Physics Letters 1997年第2期14卷 117-120页

作者： LIU Jin-liang ZHANG Ya-zhou LI Chuan-lu TAN Qi-mei CHEN Guo-qiang WANG Yong Department of Applied Physics National University of Defense TechnologyChangsha 410073

Microwave generation from a resonant cavity surrounding oscillating virtual cathode,which is produced by non-homogeneous electron beams,is studied *** microwave power is measured by using the crystal detector and frequencies are measured by using the heterodyne technique.A single microwave pulse contains two microwave signals with different frequencies,one peak power is 1.1.MW at 5.03GHz and the other is 0.56MW at 5.24GHz,and their 3dB bandwidths are 1. and 25 MHz,respectively.

关键词： technique. Microwave microwave

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基于属性粒化聚类与回声状态网络的末制导雷达故障诊断

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上海交通大学学报 2018年第9期52卷 1112-1119页

作者：逯程[１] 徐廷学[１] 王虹[２] [１]海军航空大学岸防兵学院，山东烟台２６４００１；[２]中央军委联合参谋部第５５研究所，北京１０００９４山东烟台264001

为了提高末制导雷达故障诊断的效率和精度,提出一种基于属性粒化聚类与回声状态网络(ESN)的故障诊断方法.定义一种基于属性值影响度的属性区分能力测量指标,并以此作为相似性度量依据,利用近邻传播(AP)聚类算法得到区分能力相当的若干... 详细信息

为了提高末制导雷达故障诊断的效率和精度,提出一种基于属性粒化聚类与回声状态网络(ESN)的故障诊断方法.定义一种基于属性值影响度的属性区分能力测量指标,并以此作为相似性度量依据,利用近邻传播(AP)聚类算法得到区分能力相当的若干属性粒,通过选取聚类中心属性来完成故障征兆属性的约简;在储备池构建中,采用Bienenstock-Cooper-Munro(BCM)规则进行连接权矩阵的预训练,在目标函数中添加L_(1.2)范数惩罚项,以提高ESN储备池对样本的动态适应性;同时,采用半阈值迭代法对模型进行求解,通过末制导雷达信号处理模块的故障诊断实例,验证了所提方法的有效性和优越性.结果表明:与BP神经网络和传统ESN模型相比,所提方法的稳定性及诊断准确率更高;将其与基于属性重要度和AP聚类的属性粒化约简算法相结合,能够进一步提高故障诊断的效率和精度,其仿真实验的训练时间仅为8.98s,诊断正确率可达95.2%.

关键词：末制导雷达属性粒化聚类回声状态网络 BCM规则故障诊断

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Universal triple I fuzzy reasoning algorithm of function model based on quotient space

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Computer Aided Drafting,Design and Manufacturing 2012年第1期22卷 49-60页

作者： lu qiang Shen Guanting and Liu Xiaoping School of Computer ＆ Information Hefei University of Technology Hefei 230009 China Engineering Research Center of Safety Critical Industry Measure and Control Technology Ministry of Education Hefei University of Technology Hefei230009 China

Aiming at the deficiencies of analysis capacity from different levels and fuzzy treating method in product function modeling of conceptual design, the theory of quotient space and universal triple I fuzzy reasoning method are introduced, and then the function modeling algorithm based on the universal triple I fuzzy reasoning method is proposed. Firstly, the product function granular model based on the quotient space theory is built, with its function granular representation and computing rules defined at the same time. Secondly, in order to quickly achieve function granular model from function requirement, the function modeling method based on universal triple I fuzzy reasoning is put forward. Within the fuzzy reasoning of universal triple I method, the small-distance-activating method is proposed as the kernel of fuzzy reasoning; how to change function requirements to fuzzy ones, fuzzy computing methods, and strategy of fuzzy reasoning are respectively investigated as well; the function modeling algorithm based on the universal triple I fuzzy reasoning method is achieved. Lastly, the validity of the function granular model and function modeling algorithm is validated. Through our method, the reasonable function granular model can be quickly achieved from function requirements, and the fuzzy character of conceptual design can be well handled, which greatly improves conceptual design.

关键词： conceptual design function modeling fuzzy reasoning universal triple I method

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