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Low-protein diet supplemented with 1. L-glutamine improves growth performance, serum biochemistry, redox status, plasma amino acids, and alters fecal microbiota in weaned piglets

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Animal Nutrition 2024年第2期17卷 144-154页

作者： jun Li jun Bai Ying Yang Zhenlong wu State Key Laboratory of Animal Nutrition and Feeding Department of Companion Animal Science China Agricultural University

Glutamine, one of the most abundant amino acids in the body, has been shown to exert various beneficial effects in pigs. However, knowledge regarding the role of dietary glutamine in low-protein diet-fed piglets remains scarce. The present study aimed to investigate the effects of different levels of L-glutamine on growth performance, serum biochemistry parameters, redox status, amino acids, and fecal microbiota in low-protein diet-fed piglets. A total of 1.8 healthy crossbred piglets(Landrace × Yorkshire)were randomly allocated into 4 groups of 4 replicate pens, with 8 piglets per pen. Piglets in the 4 groups were fed with corn and soybean meal-based low-protein diets(crude protein level, 1.%) that contained0%, 1., 2%, and 3% L-glutamine, respectively, for 28 d. Pigs administered 1. L-glutamine had greater body weight on d 28 and average daily gain(ADG, P 1., whereas a lower feed to gain ratio(F:G) from d 1.o 28(P 1., compared to the other three groups. Besides, lower body weight on d 1. and 28, ADG,average daily feed intake, and higher F:G from d 1. to 28 and d 1.to 28 were observed in response to 2%and 3% L-glutamine treatments than 0% and 1. L-glutamine treatments(P 1.. Moreover, 1. Lglutamine reduced serum glucose, malondialdehyde, hydrogen peroxide concentrations and inhibited aspartate aminotransferase, alanine aminotransferase, myeloperoxidase activities in low-protein diet-fed piglets on d 1., with concomitantly upregulated catalase, total superoxide dismutase activities and glutathione level(P 1.(P 1. L-glutamine upregulated the serum glutamine, lysine, methionine, tyrosine, and reduced plasma valine content(P 1. Lglutamine upregulated the abundance of p＿75＿a5, Clostridium, Lactobacillus, Prevotellaceae＿Prevotella,and Gemmiger in the stool of piglets on d 1., with the Streptococcus lev

关键词： Glutamine Low protein diet Pig Redox status Amino acid Microbiota

Chimeric Monkey Born Alive with a High Contribution of Donor Cells

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Neuroscience Bulletin 2024年第6期40卷 849-851页

作者： Jia Huang jun wu Department of Molecular Biology University of Texas Southwestern Medical CenterDallasTX75390USA Hamon Center for Regenerative Science and Medicine University of Texas Southwestern Medical CenterDallasTX75390USA Cecil H.and Ida Green Center for Reproductive Biology Sciences University of Texas Southwestern Medical CenterDallasTX75390USA

Chimeras,which consist of cells from different individuals or different species,represent an important tool in biological *** in the early twentieth century,studies on chimeras have been focusing on understanding fundamental genetic and cellular developmental *** the advances in genetic engineering and embryonic stem cell(ESC)technology,chimeras have become an important tool for the generation of transgenic animals.

关键词： mechanisms advances developmental

Impact response and energy absorption of metallic buffer with entangled wire mesh damper

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Defence Technology（防务技术） 2024年第5期35卷 137-150页

作者： Chao Zheng jun wu Mangong Zhang Xin Xue Institute of Metal Rubber&Vibration Noise School of Mechanical Engineering and AutomationFuzhou UniversityFuzhou 350116China wuhan Second Ship Design and Research Institute Wuhan 430205China

An innovative metallic buffer consisting of series-connected hat-shaped entangled wire mesh damper(EWMD)and parallel springs are proposed in this work to enhance the reliability of engineering *** impact response and the energy dissipation mechanism of hat-shaped EWMD under different quasi-static compression deformations(2-7 mm)and impact heights(1.0-200 mm)are investigated using experimental and numerical *** results demonstrate distinct stages in the quasi-static mechanical characteristics of hat-shaped EWMD,including stiffness softening,negative stiffness,and stiffness *** loss factor gradually increases with increasing compression deformation before entering the stiffness hardening *** impact loads,the hat-shaped EWMD exhibits optimal impact energy absorption when it enters the negative stiffness stage(1.0 mm),resulting in the best impact isolation effect of metallic ***,the impact energy absorption significantly decreases when hat-shaped EWMD enters the stiffness hardening ***,quasi-static compression analysis after experiencing different impact loads reveals the disappearance of the negative stiffness ***,with increasing impact loads,the stiffness hardening point progressively shifts to an earlier stage.

关键词： Metallic buffer Hat-shaped EWMD Drop impact Energy absorption characteristics Mechanical behavior

A buffer overflow detection and defense method based on RiSC-V instruction set extension

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Cybersecurity 2024年第2期7卷 28-43页

作者： Chang Liu Yan-jun wu Jing-Zheng wu Chen Zhao Intelligent Software Research Center Institute of SoftwareChinese Academy of SciencesBejingChina University of Chinese Academy of Sciences BeijingChina State Key Laboratory of Computer Science Institute of SoftwareChinese Academy of SciencesBeijingChina

Buffer overflow poses a serious threat to the memory security of modern operating *** overwrites the con-tents of other memory areas by breaking through the buffer capacity limit,destroys the system execution environ-ment,and provides implementation space for various system attacks such as program control flow *** makes it a wide range of harms.A variety of security technologies have been proposed to deal with system security problems including buffer *** example,No eXecute(NX for short)is a memory management technology commonly used in Harvard *** can refuse the execution of code which residing in a specific memory,and can effectively suppress the abnormal impact of buffer overflow on control ***,in recent years,it has also been used in the field of system security,deriving a series of solutions based on NX technology,such as ExecShield,DEP,StackGuard,***,these security solutions often rely too much on the processor archi-tecture so that the protection coverage is insufficient and the accuracy is *** in the emerging system architecture field represented by RiSC-V,there is still a lack of effective solutions for buffer overflow *** the continuous rapid development of the system architecture,it is urgent to develop defense methods that are applicable to different system application environments and oriented to all executable memory spaces to meet the needs of system security ***,we propose BOP,A new system memory security design method based on RISC-V extended instructions,to build a RISC-V buffer overflow detection and defense system and deal with the buffer overflow threat in *** to this method,NX technology can be combined with program control flow analysis,and Nx bit mechanism can be used to manage the executability of memory space,so as to achieve a more granular detection and defense of buffer overflow attacks that may occur in RISC-V system

关键词： RISc-V Operating system security Buffer overflow Control flow hijacking Nx bit Xibop

Pion-photon and kaon-photon transition distribution amplitudes in the Nambu–Jona-Lasinio model

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Chinese Physics C 2024年第8期48卷 94-103页

作者： Jin-Li Zhang jun wu Department of Mathematics and Physics Nanjing Institute of TechnologyNanjing 211167China National Laboratory of Solid State Microstructures Department of PhysicsNanjing UniversityNanjing 210093China

The Nambu–Jona-Lasinio model is utilized to investigate the pion-and kaon-photon leading-twist transition distribution amplitudes using proper time ***,the properties of the vector and axial vector pion-photon transition distribution amplitudes are examined,and the results meet the desired *** study involves sum rule and polynomiality *** vector and axial vector pion-photon transition form factors that are present in theπ^(+)→γe^(+)νprocess are the first Mellin moments of the pion-photon transition distribution *** vector transition form factor originates from the internal structure of hadrons,the axial current can be coupled to a pion,this pion is virtual,and its contribution will be present independently of the external *** kaon transition form factors are *** vector form factor's value at zero momentum transfer is determined by the axial anomaly,while this is not the case for the axial *** vector and axial form factors,as well as the neutral pion vector form factor F_(πγγ)(t),are *** to our findings,the pion axial transition form factor is harder than the vector transition form factor and harder than the electromagnetic form *** also discuss the link betweenπ−γandγ−πtransitions distribution amplitudes.

关键词： transition form factors NJL model transition distribution amplitudes

Diabetes remission and nonalcoholic fatty pancreas disease

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World Journal of Diabetes 2024年第7期15卷 1390-1393页

作者： Wen-jun wu Department of Endocrinology Jinshan Branch of Shanghai Sixth People’s HospitalShanghai 201500China

This editorial focuses on the relationship between nonalcoholic fatty pancreas disease(NAFPD)and the development and remission of type 2 diabetes(T2D).NAFPD is characterized by intrapancreatic fatty deposition associated with obesity and not associated with alcohol abuse,viral infections,and other *** fat deposition in the pancreas is associated with the development of T2D,and the underlying mechanism is lipotoxicβ-cell ***,the results on the relationship between intrapancreatic fat deposition(IPFD)andβ-cell function are *** of the therapeutic approach,weight loss improves IPFD,glycemia,andβ-cell *** imaging is valuable for clinically monitoring and evaluating the management of T2D.

关键词： Diabetes remission Type 2 diabetes Pancreatic fat content βcell function Weight loss

Spatially explicit reconstruction of cropland cover in Europe from AD 1.00 to 2000

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Science China Earth Sciences 2024年第9期67卷 2953-2971页

作者： jun LI Yu YE Xiuqi FANG Diyang ZHANG Zhilei wu Faculty of Geographical Science Beijing Normal UniversityBeijing 100875China Key Laboratory of Environmental Change and Natural Disaster Ministry of EducationBeijing Normal UniversityBeijing 100875China College of Geographical Science Qinghai Normal UniversityXining 810016China

One of the challenges in global change research is the significant uncertainty in global historical land use and land cover(LUCC)datasets,which are widely used as foundational *** addition to the regional cropland area reconstructions,improving the grid allocation method is another feasible way to raise the reliability of historical LUCC *** this study,an integrated reconstruction of the national cropland areas over the past 200 years was developed for 36 European *** that,the allocation algorithm was built using physiogeographic variables and historical city sites for accounting for land suitability and cultivation preferences,***,cropland data in Europe with a spatial resolution of 5′×5′at five time sections from AD 1.00 to 2000 were generated using the optimal allocation algorithm in accordance with the stages of the regional *** results were as follows:(1.The dominant factors governing the distribution of croplands in Europe vary at different agricultural stages,but the results can be merged *** suitability was more optimal for allocation during the modern agricultural stage(AD 1.50 and 2000);the priority index combined with land suitability and cultivation preference was more reasonable for allocation during the traditional agricultural stage(AD 1.00).The average of the allocations by priority index and the land suitability could be adopted as the allocation results during the transitional stage(AD 1.50 and 1.00)because the grids for absolute differences within±1. and±20 percentage points between the results obtained from the above two allocations were above 80% and 95%,respectively,which means the two allocation results could be merged.(2)Over the past 200 years,the total cropland area in Europe first increased to a peak in AD 1.00 and then ***,the centre of the higher cropland fraction shifted from the western part of Europe in AD 1.00 to the eastern part of the continent after AD 1.50.(3)

关键词： Land use and land cover change Historical cropland Gridding allocation Europe Past 200 years

Occurrence and possible sources of antibiotic resistance genes in seawater of the South China Sea

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Frontiers of Environmental Science & Engineering 2024年第9期18卷 27-38页

作者： Jian Lu jun wu Cui Zhang Jianhua Wang Xia He CAS Key Laboratory of Coastal Environmental Processes and Ecological Remediation Yantai Institute of Coastal Zone Research(YIC)Chinese Academy of Sciences(CAS)Shandong Key Laboratory of Coastal Environmental ProcessesYICCASYantai 264003China Yantai Research Institute Harbin Engineering UniversityYantai 264006China College of Environmental Science and Engineering Guilin University of TechnologyGuilin 541006China

Antibiotic resistance genes(ARGs)might have great effect on ecological security and human *** are important reservoirs that receive tremendous amounts of pollutants ***,information on the proliferation of ARGs in seawater is still *** study performed field sampling to investigate the occurrence and distribution of ARGs in seawater of the South China Sea,which is the deepest and largest sea in *** results showed that the total absolute abundances of ARGs in seawater samples ranged from 2.1.1.^(3)to 2.3×1.^(4)copies/mL,with an of 5.0×1.^(3)copies/mL and a range of 2.2×1.^(3)–1.8×1.^(4)copies/mL for those with mobile genetic elements(MGEs).Genes resistant to multidrug,aminoglycoside,tetracycline,and fluoroquinolone antibiotics accounted for 77.3%–88.6%of total ARGs in *** and Cyanobacteria represented 32.1.–56.2%and 30.4%–49.5%of microbial community,***_MIT931. and Clade_la were the prevalent genera in seawater of the South China *** co-occurrence relationship existed among ARGs,MGEs,and *** activities had critical influence on ARGs and *** wastewater,wastewater treatment plant effluent,sewage,aquaculture tailwater,and runoff were determined as the important sources of ARGs in seawater of the South China Sea based on positive matrix factorization analysis.

关键词： The South China Sea Antibiotic resistance genes Mobile genetic element Source apportionment

Weakly Approximate Diagonalization of Homomorphisms into Finite von Neumann Algebras

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Acta Mathematica Sinica,English Series 2024年第9期40卷 2187-2194页

作者： Wen Hua QIAN jun Hao SHEN Wen Ming wu School of Mathematical Sciences Chongqing Normal UniversityChongqing 401331P.R.China Department of Mathematics and Statistics University of New HampshireDurhamNH 03824USA

Let A be a unital C^(∗)-algebra and B a unital C^(∗)-algebra with a faithful traceτ.Let n be a positive *** give the definition of weakly approximate diagonalization(with respect toτ)of a unital homomorphismφ:A→Mn(B).We give an equivalent characterization of McDuff Ⅱ_(1. *** show that,if A is a unital nuclear C^(∗)-algebra and B is a type Ⅱ_(1. factor with faithful traceτ,then every unital^(∗)-homomorphism φ:A→M_(n)(B)is weakly approximately *** B is a unital simple infinite dimensional separable nuclear C^(∗)-algebra,then any finitely many elements in Mn(B)can be simultaneously weakly approximately diagonalized while the elements in the diagonals can be required to be the same.

关键词： Weakly approximately diagonalizable McDuff factors nuclear hyperfinite