检索结果-南通市图书馆

Analysis of RNA Recognition and Binding Characteristics of OsCPPR1.Protein in Rice

在线全文

学校读者我要写书评

暂无评论

Rice science 2024年第2期31卷 215-225,I0032-I0035页

作者： ZHENG Shaoyan CHEN junyu LI Huatian LIU Zhenlan LI Jing ZHUANG Chuxiong State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources/Guangdong Laboratory for Lingnan Modern Agriculture/College of Life Sciences South China Agricultural UniversityGuangzhou 510642China

Pentatricopeptide repeat(PPR)proteins represent one of the largest protein families in plants and typically localize to organelles like mitochondria and *** contrast,CYTOPLASMLOCALIZED PPR1.OsCPPR1.is a cytoplasm-localized PPR protein that can degrade OsGOLDENLIKE1.OsGLK1.mRNA in the tapetum of rice ***,the mechanism,by which OsCPPR1.recognizes and binds to OsGLK1.transcripts,remains *** protein structure prediction and macromolecular docking experiments,we observed that distinct PPR motif structures of OsCPPR1.exhibited varying binding efficiencies to OsGLK1.***,RNA-electrophoretic mobility shift assay experiment demonstrated that the recombinant OsCPPR1.can directly recognize and bind to OsGLK1.mRNA in *** further confirmed that the mutations in the conserved amino acids in each PPR motif resulted in loss of activity,while truncation of OsCPPR1.decreased its binding *** findings collectively suggest that it may require some co-factors to assist in cleavage,a facet that warrants further exploration in subsequent studies.

关键词： OsCPPR1 RNA recognition and binding pentatricopeptide repeat rice

Single depth image 3D face reconstruction via domain adaptive learning

在线全文

学校读者我要写书评

暂无评论

Frontiers of Computer Science 2024年第1期18卷 259-261页

作者： Xiaoxu CAI Jianwen LOU Jiajun BU junyu DONG Haishuai WANG Hui YU College of Computer Science and Technology Zhejiang UniversityHangzhou 310013China School of Creative Technologies University of PortsmouthPortsmouth PO12DJUK College of Computer Science and Technology Ocean University of ChinaQingdao 266100China

1.Introduction In this paper,we propose a novel domain-adaptive reconstruction method that effectively leverages deep learning and synthetic data to achieve robust 3D face reconstruction from a single depth *** method applies two domain-adaptive neural networks for predicting head pose and facial shape,*** networks undergo training with a customized domain adaptation strategy,using a combination of auto-labeled synthetic and unlabeled real data.

关键词： networks image learning

Enhancing Geological Understanding and Identifying Gold Anomalies in the Ailaoshan Orogen

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Acta Geologica Sinica(English Edition) 2024年第2期98卷 441-453页

作者： ZHAO Shiyu YANG Lin SONG Yiwei DONG Yuntao FENG Lihao LI Huajian WU junyu WANG Qingfei State Key Laboratory of Geological Processes and Mineral Resources China University of GeosciencesBeijing 100083China Xi’an Center of Mineral Resources Survey China Geological SurveyXi’an 710010China Yunnan Gold Mining Industry Group Kunming 650299China Jiangxi Provincial Key Laboratory of Genesis and Prospect for Strategic Minerals East China University of TechnologyNanchang 330013China Frontiers Science Center for Deep-time Digital Earth China University of Geosciences(Beijing)Beijing 100083China

The Ailaoshan Orogen in the southeastern Tibet Plateau,situated between the Yangtze and Simao blocks,underwent a complex structural,magmatic,and metamorphic evolution resulting in different tectonic subzones with varying structural lineaments and elemental *** elements can conceal or reduce anomalies due to the mutual effect between different anomaly *** the whole zone into subzones based on tectonic settings,ore cluster areas,or sample catchment basins(Scb),geochemical and structural anomalies associated with gold(Au)mineralization have been identified utilizing mean plus twice standard deviations(Mean+2STD),factor analysis(FA),concentration-area(CA)modeling of stream sediment geochemical data,and lineament density in both the Ailaoshan Orogen and the individual *** FA in the divided 98 Scbs with 6 Scbs containing Au deposits can roughly ascertain unknown rock types,identify specific element associations of known rocks and discern the porphyry or skarn-type Au *** with methods of Mean+2STD and C-A model of data in the whole orogen,which mistake the anomalies as background or act the background as anomalies,the combined methods of FA and C-A in the separate subzones or Scbs works well in regional metallogenic potential *** of lineament densities with a 1.-km circle diameter is not suitable to locate Au deposits because of the delineated large areas of medium-high lineament *** contrast,the use of circle diameters of 1.3 km or 1.7 km in the ore cluster scale delineates areas with a higher concentration of lineament density,consistent with the locations of known Au *** analyzing the map of faults and Au anomalies,two potential prospecting targets,Scbs 1.and 63 with a sandstone as a potential host rock for Au,have been identified in the Ailaoshan *** use of combined methods in the divided subzones proved to be more effective in improving geological understanding and identifying

关键词： minerology geochemistry gold stream sediment sample catchment basin concentration-area model lineament density Ailaoshan Orogen

Microscopic and spectroscopic analysis of atmospheric iron-containing single particles in Lhasa,Tibet

在线全文

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2024年第7期141卷 40-50页

作者： junyu Chen Daobin Zhang Yiran Fu Jinhu Wang Xiaomei Cui Ci-ren Qu-zong Qiangying Zhang Chan Jin Bu Duo School of Ecology and Environment Tibet UniversityLhasa 850000China Shanghai Institute of Applied Physics Chinese Academy of SciencesShanghai 201800China Institute of Tibetan Plateau Research Chinese Academy of SciencesBeijing 100101China

The Tibetan Plateau,known as the“Third Pole”,is currently in a state of perturbation caused by intensified human *** this study,56 samples were obtained at the five sampling sites in typical area of Lhasa city and their physical and chemical properties were investigated by TEM/EDS,STXM,and NEXAFS *** careful examination of 3387single particles,the results showed that Fe should be one of the most frequent metal *** Fe-containing single particles in irregular shape and micrometer size was about7.8%and might be mainly from local ***,the Fe was located on the subsurface of single particles and might be existed in the form of iron ***,the core-shell structure of iron-containing particles were about 38.8%and might be present as single-,dual-or triple-core shell structure and multi-core shell structure with the Fe/Si ratios of 1..5,1..5,2.9 and 1.2,***,iron and manganese were found to coexist with identical distributions in the single particles,which might induce a synergistic effect between iron and manganese in catalytic ***,the solid spherical structure of Fe-containing particles without an external layer were about 53.4%.The elements of Fe and Mn were co-existed,and might be presented as iron oxide-manganese oxide-silica ***,the ferrous and ferric forms of iron might be *** information can be valuable in expanding our understanding of Fe-containing particles in the Tibetan Plateau atmosphere.

关键词： Fe-containing single particle Irregular shape Core-shell structure Solid spherical structure Transmission electron microscopy Synchrotron X-ray microscopy

Drug-loading ZIF-8 for modification of microporous bone scaffold to promote vascularized bone regeneration

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2024年第6期35卷 358-364页

作者： Xin Zhang junyu Chen Xiang Pei Linxin Yang Liang Wang Luona Chen Guangmei Yang Xibo Pei Qianbing Wan Jian Wang State Key Laboratory of Oral Diseases National Clinical Research Center for Oral DiseasesChengdu 610041China Department of Prosthodontics West China Hospital of StomatologySichuan UniversityChengdu 610041China

Surface modification of microporous bone scaffolds using nanoparticles has been broadly studied in bone tissue *** at improving vascularized bone regeneration(VBR),zeolitic imidazolate framework-8(ZIF-8)was encapsulated with dimethyloxallyl glycine(DMOG)and the drug-carrying nanoparticles(D@Z)could be uniformly coated onto the surface of the bone *** osteogenic and angiogenic actions of D@Z are closely correlated with the amount of slowly released DMOG,and in general,exhibited a favorable ***,the D7.5@Z group,which showed the greatest capacity to induce in vitro osteogenesis-angiogenesis coupling,was utilized for surface modification of the bone *** processes including phosphate-containing compound metabolic process,cell differentiation,cell proliferation and cell motility might contribute to enhanced ability to induce VBR by the coated scaffold and signaling pathways such as Rap1.Ras,phosphatidylinositol 3-kinase/protein kinase B(PI3K-AKT)and vascular endothelial growth factor(VEGF)signaling pathways participated in these ***,as depicted by in vitro real time-polymerase chain reaction(RT-PCR),Western blot(WB)and in vivo cranial bone defect model,the microporous scaffold coated with nano-D7.5@Z greatly promoted *** conclude,nano-D@Z has significant promise for practical application in modification of microporous bone scaffolds to enhance VBR,and DMOG loading quantity has a beneficial influence on D@Z to improve osteogenesis-angiogenesis coupling.

关键词： Drug-loading nanoparticles Surface coating Microporous bone scaffold Vascularization bone regeneration

Oriented Generation of Novel Thermo-Sensitive Genic Male Sterile Lines with Improved Grain Shape and Outcrossing Rate in Early-Season Rice

在线全文

学校读者我要写书评

暂无评论

Rice science 2024年第2期31卷 129-133,I0001-I0016页

作者： ZHANG Huali CHEN junyu LI Ruiqing WANG Huimei DAI Dongqing LIANG Minmin WU Mingyue MA Liangyong State Key Laboratory of Rice Biology and Breeding/Chinese National Center for Rice Improvement China National Rice Research InstituteHangzhou 310006China

Two-line hybrid rice with excellent quality is preferred in the Chinese ***,there is a trade-off between reducing costs for hybrid seed production and lowering the outcrossing rate of the sterile line,which is largely determined by the stigma exsertion rate(SER).In this study,we constructed mutants of male sterility lines with improved grain length(GL)and SER in three elite early-season indica rice varieties through targeted manipulation of the TMS5 and GS3 genes using CRISPR/Cas9-mediated multiplex *** obtained a series of marker-free gs3 single mutants and gs3tms5 double mutants with significantly higher SER,longer grains,and increased 1.00-grain weight compared with the wild type(WT).Importantly,the typically thermo-sensitive genic male sterile(TGMS)trait with a higher SER was observed in gs3tms5 mutants,and their F1.hybrids exhibited remarkable improvements in grain shape and yield-related *** findings provided an efficient method to generate new valuable TGMS germplasm with improved SER through the mutagenesis of GS3 and TMS5 synergistically,and demonstrated that GS3 had pleiotropic effects on grain size,SER,and grain quality in early-season indica rice.

关键词： sterile elite season

PDGFRB mutation causes intracranial aneurysm

在线全文

学校读者我要写书评

暂无评论

Journal of Genetics and Genomics 2024年第9期51卷 978-981页

作者： junyu Liu Chunling Wang Enyu Huang Luming Wang Chengchao Wu Weixi Jiang Mei Wu Xiuru Zhang Junxia Yan Yeqi Wang Jingjing Zhang Department of Neurosurgery XiangYa HospitalCentral South UniversityChangshaHunan 410008China Department of Pharmacology Kyoto University Graduate School of MedicineKyoto 606-8501Japan Key Laboratory for Biorheological Science and Technology of Ministry of Education College of BioengineeringChongqing UniversityChongqing 400044China Affiliated Hospital of Guangdong Medical University&Zhanjiang Key Laboratory of Zebrafish Model for Development and Disease Guangdong Medical UniversityZhanjiangGuangdong 524001China Department of Epidemiology and Health Statistics XiangYa School of Public HealthCentral South UniversityChangshaHunan 410006China Hunan Provincial Key Laboratory of Clinical Epidemiology XiangYa School of Public HealthCentral South UniversityChangshaHunan 410006China

Intracranial aneurysm(IA)is characterized by defects in the middle muscular layer and pathological dilatation of cerebral *** rupture of IA,resulting in aneurysmal subarachnoid hemorrhage,poses a substantial public health problem,especially in developed countries,due to its high mortality,morbidity,and socioeconomic burden(Bakker and Ruigrok,2021..Understanding the risk factors for IA is critical for disease *** numerous studies(Yan et al.,201.;Santiago-Sim et al.,201.;Barak et al.,2021.Liu et al.,2021.have highlighted familial aggregation of IA and identified candidate genes such as ADAMTS1.,THSD1.ANK3,and PPIL4,the mechanisms underlying IA formation and rupture remain unclear.

关键词： al. aneurysm rupture

A 9.5-kb deletion in the 1.t intron of OsMADS51.enhances temperature sensitivity in rice

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The Crop Journal 2024年第4期12卷 1031-1040页

作者： Lei Zhao Haifei Hu junyu Chen Chongrong Wang Yibo Chen Hong Li Daoqiang Huang Zhidong Wang Degui Zhou Rong Gong Yangyang Pan Junliang Zhao Liangyong Ma Shaochuan Zhou Rice Research Institute Guangdong Academy of Agricultural SciencesGuangzhou 510640GuangdongChina State Key Laboratory of Rice Biology and Chinese National Center for Rice Improvement China National Rice Research InstituteHangzhou 310006ZhejiangChina Guangdong Laboratory for Lingnan Modern Agriculture Guangzhou 510640GuangdongChina Key Laboratory of Genetics and Breeding of High Quality Rice in Southern China(Co-construction by Ministry and Province) Ministry of Agriculture and Rural AffairsGuangzhou 510640GuangdongChina Guangdong Rice Engineering Laboratory Guangzhou 510640GuangdongChina Guangdong Key Laboratory of New Technology in Rice Breeding Guangzhou 510640GuangdongChina

Temperature is an important environmental factor affecting heading date of *** its importance,genes responsible for temperature-sensitive heading in rice have remained *** previous study identified a quantitative trait locus qHd1.which advances heading date under high temperatures.A 9.5-kb insertion was found in the first intron of OsMADS51.in indica variety Zhenshan 97(ZS97).However,the function of this natural variant in controlling temperature sensitivity has not been *** this study,we used CRISPR/Cas9 to knock out the 9.5-kb insertion in *** conducted under cotrolled conditions in phytotrons confirmed that deletion increased temperature sensitivity and advanced heading by downregulating the expression level of ***-hybrid assays in yeast,ChIP-quantitative polymerase chain reaction,electrophoretic mobility shift,and luciferase-based transient transactivation assays collectively confirmed that OsMADS51.affects heading date by regulation of heading date gene *** further determined that the long non-coding RNA HEATINR is generated from the first intron of OsMADS51.offering an explanation for how the 9.5-kb insertion affects temperature *** also found that OsMADS51.was strongly selected in early/late-season rice varieties in South China,possibly accounting for their strong temperature *** insights not only advance our understanding of the molecular mechanisms underlying the temperature-responsive regulation of heading date in rice but also provide a valuable genetic target for molecular breeding.

关键词： OsMADS51 Insertion Long non-coding RNA Oryza sativa

Effects of typical karst tourist town on the Lijiang River water: from heavy metals to N-nitrosamines

在线全文

学校读者我要写书评

暂无评论

Journal of Earth Science 2024年

作者： Yuanyu Shan Yuru Su Xinli Xing Bingquan Zhu Honghu Zeng Yuan Zhang junyu Li Xiaoyu Yan Wenwen Chen Benjian Li College of Environmental Science and Engineering， Guilin University of Technology School of Environmental Studies， China University of Geosciences State Key Laboratory of Biogeology and Environmental Geology， China University of Geosciences College of arts， Guilin University of Technology College of arts and communication， China University of Geosciences 430070 China

N-nitrosamines are nitrogenous organic pollutants with high carcinogenicity to human. Heavy metal pollution in aquatic system is currently a major environmental problem. Tourism in typical karst areas may influence the environment through wastewater discharge. However， it remains unclear whether these activities would cause water pollution. To evaluate the impact of tourism activities in typical tourist towns， this study investigated the occurrence and sources of 1. N-nitrosamines， eight heavy metals （HMs）， and dissolved inorganic nitrogen （DIN） in the Lijiang River and its tributaries. Seven N-nitrosamines were detected as the dominant compounds in N-nitroso-N-ethylaniline （NEA， average of 24.8 ng/L） and N-nitroso-l-proline （NPRO， 20.4 ng/L）， while especially low concentrations of HMs （Mn， Cu， As， Ni， Cr， Co， Pb， and Cd） and DIN (NH4+-N， NO2--N， and NO3--N) were observed. The most important influencing factors were seasonal factors， followed by land-use type and mainstem and tributary factors. Principal component analysis revealed that in the city with developed tourism and relatively less heavy industry， aquaculture and agricultural wastewater were identified as the primary sources of N-nitrosamines. Meanwhile， domestic sewage and agricultural wastewater were found to be the main sources of HMs and DIN， respectively. The ecological risk assessments for all pollutants are relatively low （1.. Therefore， N-nitrosamines， HMs， and DIN pollution caused by tourist activities pose a negligible risk to the Lijiang River.

关键词：