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Acta Pharmacologica Sinica 2003年第12期 167-167页

作者： GONG Xiao-Hui, HU Xiao-Wei, SUN Bo Laboratory of Respirology and intensive care, Children’s hospital, Fudan university, Shanghai 200032, china

BACKGROUND: Though inhaled nitric oxide (iNO) improved oxygenation but had no effect on mortality in randomized clinical trial for acute respiratory distress syndrome (ARDS), its efficacy in modulation of inflammation and antioxidant capability in airway and alveolar epithelial cells in mature lungs remains to be verified. As iNO is usually used in hyperoxic condition, it may alter surfactant lipid de novo synthesis in inflammatory lung. Despite the fact that NO may potentiate damage to surfactant proteins and inhibit surfactant phospholipid synthesis, iNO is still considered an alternative and encouraging therapy in intractable respiratory failure to obviate more invasive and expensive strategies. OBJECTIVE: To investigate whether hyperoxia and/or inhaled nitric oxide (iNO) may affect de novo synthesis of phosphatidylcholine (PC) in mature lungs with inflammatory injury. METHODS: Healthy adult S-D rats were first assigned into a normal control group (C) or a group with lipopolysaccharides (2 mg/kg iv)

关键词： in Effects of inhaled nitric oxide on de novo synthesis of phosphatidylcholine in adult rat lungs with endotoxin-induced inflammatory injury on of with

产前应用单疗程及多疗程地塞米松对早产儿脑发育的影响

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实用儿科临床杂志 2009年第6期24卷 467-468,474页

作者：陈丽娟程秀永郑州大学第三附属医院NICU 郑州450052 解放军第159医院儿科

目的探讨产前应用单疗程及多疗程地塞米松对早产儿脑发育的影响。方法选择本院2005年8月-2007年3月NICU收治的28～34周的早产儿118例,按母亲产前应用地塞米松的情况分为对照组、单疗程组、多疗程组。对照组未用地塞米松;单疗程应用地塞... 详细信息

目的探讨产前应用单疗程及多疗程地塞米松对早产儿脑发育的影响。方法选择本院2005年8月-2007年3月NICU收治的28～34周的早产儿118例,按母亲产前应用地塞米松的情况分为对照组、单疗程组、多疗程组。对照组未用地塞米松;单疗程应用地塞米松10 mg,1次/d,肌肉注射,3 d为1个疗程,仅用1个疗程;多疗程组应用地塞米松2个疗程以上。3组早产儿出生后均予对症支持治疗。纠正胎龄至预产期后行新生儿20项行为神经测定(NBNA),纠正胎龄至出生3、6、12个月时采用中国儿童发展中心(CDCC)制定的婴幼儿智力发育指数(MDI)和运动发育指数(PDI)量表进行检测。采用SPSS 11.0软件进行统计学分析。结果纠正胎龄达预产期时及达预产期后7 d单疗程组NBNA评分明显高于对照组及多疗程组(Pa<0.05)。纠正胎龄至出生3、6个月时行CDCC评分,单疗程组MDI和PDI均明显高于对照组及多疗程组(Pa<0.05);12个月多疗程组MDI和PDI明显低于单疗程组及对照组(Pa<0.05),单疗程组显著高于对照组(Pa<0.05)。结论产前单疗程应用地塞米松能明显提高早产儿近、远期预后;多疗程GCS对早产儿神经系统近、远期发育均有一定的不良影响。

关键词：地塞米松脑发育婴儿,早产

A Combined Clinical and MRI Approach for Outcome Prediction in Mild Traumatic Brain Injury with Negative CT Scans

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A Combined Clinical and MRI Approach for Outcome Prediction ...

2011年浙江省神经外科学学术年会

作者： Department of Neurosurgery,Affiliated Municipal hospital of Taizhou university school of medicine,318000,Taizhou,Zhejiang,china. Yong JIN Zhi- Qiang BAI

Objective The purpose of this study was to predict outcome at 6 months for mild Traumatic Brain Injury(MTBI) patients with negative head computed tomography(CT) scans by combining clinical and magnetic resonance imaging(MRI) *** and Methods This prospective study took place between June 2008 and June 2010 in a Neurosurgical intensive care unit in Tai-zhou,*** criteria were MTBI patients with negative head CT scans within the first 24 hours after trauma and with MRI-positive within the first 72 hours after *** clinical neurological symptoms were assessed during the first administration:Nausea and/or vomiting,Feeling depressed,Forgetfulness and Poor *** and T2* acquisitions on MRI were used in order to localize brain *** linked regions(clusters) were *** was assessed at 6 months post-trauma using the Glasgow Outcome Scale- Extended(GOSE).Results 45 patients were included: 10 had Unfavorable outcome(GOSE 1-6) and 35 had favorable outcome(GOSE 7-8).Lesions in the clusters "The left lower frontal lobe","The left anterior temporal lobe" and the presence of Feeling depressed or Poor concentration were associated with poor outcome in multivariate *** combined clinical and MRI approach gives a much better prediction than MRI approach only(P<0.01),with an area under the ROC curve of 0.98(95 %CI,0.95-1.00).Conclusions These data suggest that MRI associated with clinical assessment improves outcome prediction in MTBI patients with negative head CT *** depressed or Poor concentration should be assessed acutely in MTBI patients with a negative head CT scan to determine whether to require further MRI scan of the brain or not,particularly the symptoms worsen.

关键词： MRI MTBI outcome negative CT

床旁静-静脉血液滤过在危重症患者中的临床应用

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中国实用内科杂志 2006年第S2期26卷 182-182,184页

作者：杨荣利李元忠洪秀琴大连市中心医院ICU 辽宁大连116033

目的探讨持续静-静脉血滤(CVVH)在治疗危重症中的作用与安全性。方法总结2002年1月至2006年1月对重症监护病房(ICU)采用 CVVH 治疗109例危重患者的临床应用情况。结果 109例患者每次血滤治疗时间为18～72 h,每例治疗总时间1～12 d。并... 详细信息

目的探讨持续静-静脉血滤(CVVH)在治疗危重症中的作用与安全性。方法总结2002年1月至2006年1月对重症监护病房(ICU)采用 CVVH 治疗109例危重患者的临床应用情况。结果 109例患者每次血滤治疗时间为18～72 h,每例治疗总时间1～12 d。并发症有:一过性低血压13例;凝血5例;出血2例;局部或全身感染3例。结论 CVVH 在危重症患者的治疗中有良好的安全性、耐受性、方便性和高效性。高质量的管理是血液滤过治疗获得成功的重要保证。

关键词：持续静-静脉血滤危重症

Mixed-microencapsulation of Rat Primary Hepatocytes and Sertoli cells Improves the Metabolic Function in a D-galactosamine and Lipopolysaccharide Induced Rat Model of Acute Liver Failure

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Mixed-microencapsulation of Rat Primary Hepatocytes and Sert...

2009香港-北京-杭州内科论坛暨2009年浙江省内科学学术年会

作者： Department of Infection and Liver Diseases,The First Affiliated hospital of Wenzhou Medical College, Wenzhou,china Ming-Hua Zheng Hai-Long Lin Yong-Ping Chen Department of intensive care unit,The First Affiliated hospital of Wenzhou Medical College, Wenzhou,china Jing-Ye Pan

Hepatocyte transplantation is an alternative to the transplantation of the whole *** compared to xenogeneic hepatocytes,primary hepatocytes have some advantages that cannot be replaced,such as a more powerful function,a smaller frequency of rejection caused by the host,et *** microencapsulation prevents the direct access of host cells to the graft,but cannot impede transfer of transplant-derived peptides,which can cross the physical *** cells are central to the immune privilege demonstrated in the testis,and their actions have been utilized to protect cell ***-microencapsulating Sertoli cells with HepG2 cells has proved to be a valuable strategy in hepatocyte ***,mixed microcapsules of primary rat hepatocytes and primary Sertoli cells may improve the metabolic function in the D-galactosamine and lipopolysaccharide induced rat model of acute liver failure.

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Molecular typing of Acinetobacter baumannii Isolated from intensive care units and other wards before and after Wenchuan earthquake

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Molecular typing of Acinetobacter baumannii Isolated from In...

中华医学会第九次全国检验医学学术会议暨中国医院协会临床检验管理专业委员会第六届全国临床检验实验室管理学术会议

作者： Mei Kang,Chuan-min Tao,Zhi-xing Chen,Yi Xie ,Liang Guo,Hong Fan,Ying Ma,Lan-lan Wang Department of Laboratory medicine,West china hospital,Sichuan university

Objectives Opportunistic pathogen of the species Acinetobacter baumannii(***) are ubiquitous in the environment,and because capable of resistance to antibiotics,*** was recognized to take responsibility for nosocomial infections,especially after disaster. Methods *** strains were collected from July to October 2007 for common patients and May 2008 victims after Wenchuan earthquake broken. Properties of antibiotic susceptibility and

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Primary soft-tissue Nocardial abscess resistant to trimethoprim-sulfamethoxazole with a complication of severe pneumonia:a case report

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Primary soft-tissue Nocardial abscess resistant to trimethop...

浙江省医学会呼吸系病分会成立三十周年庆典活动暨2008年呼吸病学学术年会

作者： Zhang gensheng,Wang pinli,Wang liuhong,Ye qin,Cui wei,Shen huahao Department of Respiratory Disease 1,Department of Radiology2,Department of Pathology3,Department of intensive care medicine4,Second hospital of Medical school of Zhejiang university.Hangzhou,310009,china

Introduction Nocardiosis is an opportunistic infection that has been noted in patients with malignancies, autoimmune diseases,long-term steroid users and trans-plant recipients.1 Lung and skin involvement are frequent...

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International Transferring Trend in Manufacturing Industry

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厦门大学学报（自然科学版） 2002年第S1期41卷 222-223页

作者： ZHAO Xin-jun 1, XU Li-hui 2 (1. school of Mechanical Engineering and Automation, Northeastern Unive rsity, Shenyang 110004, china 2. school of Business Administration, Northea stern university, Shenyang 110004, china)

This paper addressed the international transferring t endency of manufacturing industry one by one as follows: (1) The developed count ries realize manufacturing industry structure upgrade reling on worldwide tr ansference not only domestic transference. On one hand, the TNCs make cross-inv estments, transnational merger & acquisition so as to achieve the optimum colloc ation of R&D resources, and obtain innovation in knowledge and technology. On th e other hand, the developed countries transfer labor and resource intensive indu stry as well as the labor-intensive link of the production chain in highly tech nology industry to the developing countries, to make their industrial structure escalation. (2) The adjustment and upgrade of manufacturing industry presents "m ulti-step type". First, the object of international transference substitutes th e capital-intensive industry and maturing industry with complicate technique fo r the industry with labor-intensive, simple technique or higher pollution, or s ubstitutes non-core complex technological procedure and parts and components fo r assembly in manufacturing process. Secondly, technology transference forms "br ain-hand and foot" pattern, i.e. the developed countries are increasingly p aying more and more attention to the research and control of core technology, th us transferring simple technique and labor-intensive procedure in higher scienc e and technology. Thirdly, the developed countries begins to transfer both capit al and technology intensive production, as well as transfer certain procedures i n higher technology production process to a few developing countries, even t o transfer parts of R & D to developing countries. (3) TNCs promote the global m anufacturing network (GMN) by recombination and transfer. TNCs organize producti on, trade, technological research and transference through foreign direct invest ment (FDI) all over the world, as a result, GMN makes the national competence no longer depend on absolu

关键词： manufacturing industry international transferrin g tendency

The predictive value of RIFLE classification on prognosis of critically ill patients with acute kidney injury treated with continuous renal replacement therapy

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The predictive value of RIFLE classification on prognosis of...

中国病理生理学会危重病医学专业委员会第八届全国大会暨中华呼吸病学会呼吸生理和重症监护学组年会

作者： LI Wen-xiong CHEN Hui-de WANG Xiao-wen ZHAO Song CHEN Xiu-kai ZHENG Yue SONG Yang Department of Surgical intensive care unit,Beijing Chaoyang hospital,Capital Medical university Beijing 100020

Background The optimal timing to start CRRT for AKI patient has not been accurately *** recent proposed RIFLE criteria for diagnosis and classification of AKI may provide a method for clinicians to decide the"optimal ... 详细信息

关键词： renal replacement therapy acute kidney injury prognosis diagnostic criteria

A Fast Fractal Image Compression Coding Method

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Journal of Shanghai university(English Edition) 2001年第1期5卷 57-59页

作者： XU Chang man 1, ZHANG Zhao yang school of Communication and Information Engineering, Shanghai university, Shanghai 200072, china school of Communication and Information Engineering Shanghai University Shanghai China

Fast algorithms for reducing encoding complexity of fractal image coding have recently been an important research topic. Search of the best matched domain block is the most computation intensive part of the fractal encoding process. In this paper, a fast fractal approximation coding scheme implemented on a personal computer based on matching in range block's neighbours is *** results show that the proposed algorithm is very simple in implementation, fast in encoding time and high in compression ratio while PSNR is almost the same as compared with Barnsley's fractal block coding .

关键词： neighbour fractal block coding range block,domain block iterated function system