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Preliminary outcome of rituximab-containing salvage regimens on relapsed or refractory B-cell non-Hodgkin’s lymphoma: single institution experience

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The Chinese-German Journal of Clinical Oncology 2006年第6期5卷 402-406页

作者： Bufei Wang Huiqiang Huang Qjng Bu Zhongjun Xia xubin lin Fenghua Wang Yuhong Li Yulong Peng Zhanhe Pan Shusen Wang Tongyu lin Wenqi Jiang Zhongzhen Guan State Key Laboratory of Oncology in Southern China Guangzhou 510060 China Department of Medical Oncology Sun Yat-sen University Cancer Center Guangzhou 510060 China

Objective： The prognosis of relapsed or refractory B-cell lymphoma is poor, with a short-term survival after conventional second-line chemotherapy, Rituximab, a chimeric anti-CD20 antigen, in combination with CHOP or CHOP-like chemotherapy may improve both disease free survival （DFS） and overall survival （OS） of naive patients, but its role in the second-line therapy for relapsed non-Hodgkin＇s Lymphoma （NHL） remains to be defined, This study aimed to evaluate the efficacy of rituximab-containing salvage regimens for relapsed or refractory NHL, and observe the toxicities. Methods： The clinical data of 54 patients, who were with relapsed or refractory NHL and treated in the Cancer Center of Sun Yat-sen University, were analyzed retrospectively, Of the 54 patients, 29 were man, 25 were women, with a median age of 52.5 years old （range 18 to 75）; 50 patients （92.6%） scored 0-1 for the ECOG performance status; for second-line international prognostic index （slPI）, 21 （38.9%） scored 0-1,30 （55.6%） scored 2 to 3, and 3 （5.6%） scored 4-5; 40 cases were diffuse large B-cell lymphoma （DLBCL）, accounting for 74.1% of all subtypes, Rituximab was administered intravenously at a dose of 375 mg/m^2 at the day before each chemotherapy cycle, The second or third-line salvage regimens included EPOCH, CHOP, DHAP, DICE, IVAC, IMVP-16 and FND, Results： Of the 54 patients, 49 received retuximab-containing salvage regimens, The objective response rate of the 45 evaluable cases was 68,8%, with a complete remission （CR） rate of 37.7%; 3 patients achieved CR after radiotherapy following rituximab-based regimens and 3 achieved CR after autologous hematopoietic stem cell transplantation, The most frequent adverse events were leucopenia, nausea and alopecia. The addition of rituximab to chemotherapy only elevated the occurrence of mild infusion-related reactions, such as chills, fever and pruritus. The median follow-up time was 18 months （range 2-86 months）; 5 patients were lost, 24 were dead （

关键词： non-Hodgkin's lymphoma chemotherapy rituximab salvage treatment

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类蜂窝状结构完全带隙二维光子晶体

光学学报 2006年第1期26卷 126-130页

作者：林旭彬陈钰杰李宝军中山大学光电材料与技术国家重点实验室广州510275

通过在二维三角晶格中引入两个完全一样的介质圆柱构成了类蜂窝状结构光子晶体,并对其光子能带进行了频域计算。借助数值方法分析了介质柱位置改变对光子能带的影响,计算结果表明,这种类蜂窝状结构二维光子晶体可以产生很宽的带隙,而且... 详细信息

通过在二维三角晶格中引入两个完全一样的介质圆柱构成了类蜂窝状结构光子晶体,并对其光子能带进行了频域计算。借助数值方法分析了介质柱位置改变对光子能带的影响,计算结果表明,这种类蜂窝状结构二维光子晶体可以产生很宽的带隙,而且在一定填充率下,可以通过调整介质柱的位置使完全光子带隙达到最大化。

关键词：光电子学光子晶体完全带隙频域方法蜂窝状结构三角晶格

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俄罗斯新型高超声速打击武器研究

战术导弹技术 2019年第1期 19-24页

作者：林旭斌张灿北京海鹰科技情报研究所北京100074

针对俄罗斯2018年披露的"匕首"和"先锋"两型高超声速打击武器,在全面梳理其基本信息的基础上,重点对两型武器的外形方案、性能指标(动力推进、制导和射程等)进行了深入的分析,并从技术路线和作战用途两个维度对比分析了俄罗斯高超声速... 详细信息

针对俄罗斯2018年披露的"匕首"和"先锋"两型高超声速打击武器,在全面梳理其基本信息的基础上,重点对两型武器的外形方案、性能指标(动力推进、制导和射程等)进行了深入的分析,并从技术路线和作战用途两个维度对比分析了俄罗斯高超声速打击武器发展的特点。俄罗斯利用现有优势,有望研发更符合现代化作战要求的高超声速打击武器,继续保持在国际高超声速武器领域中的优势地位。

关键词：高超声速打击武器匕首先锋精确制导

Can perfluorooctanoic acid be effectively degraded usingβ-PbO_(2)reactive electrochemical membrane?

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Chinese Chemical Letters 2024年第7期35卷 196-199页

作者： xubin Qian Lei Xu Xu Ge Zhun Liu Cheng Fang Jianbing Wang Junfeng Niu College of Environmental Science and Engineering North China Electric Power UniversityBeijing 102206China College of Water Resources and Hydropower Engineering North China Electric Power UniversityBeijing 102206China Research Center for Eco-Environmental Engineering Dongguan University of TechnologyDongguan 523808China Global Centre for Environmental Remediation(GCER) University of NewcastleCallaghanNSW 2308Australia School of Chemical and Environmental Engineering China University of Mining and Technology(Beijing)Beijing 100083China

Aqueous perfluorooctanoic acid(PFOA)elimination has raised significant concerns due to its persistence and ***β-PbO_(2)plate anodes have shown efficient mineralization of PFOA,it remains unclear whether PFOA can be effectively degraded usingβ-PbO_(2)reactive electrochemical membrane(REM).Herein,we assessed the performance of Ti/SnO_(2)-Sb/La-PbO_(2)REM for PFOA removal and proposed a possible degradation *** a current density of 10 mA/cm2and a membrane flux of 8500(liters per square meter per hour,LMH),the degradation efficiency of 10 mg/L PFOA was merely8.8%,whereas the degradation efficiency of 0.1 mg/L PFOA increased to 96.6%.Although the porous structure of theβ-PbO_(2)REM provided numerous electroactive sites for PFOA,the generated oxygen bubbles in the pores could block the pore channels and adsorb PFOA *** hindered the protonation process and significantly impeded the degradation of high-concentration *** experiments indicated that·OH played dominant role in PFOA *** electrical energy per order to remove 0.1 mg/L PFOA was merely 0.74 Wh/L,which was almost an order of magnitude lower than that of other anode *** study presents fresh opportunities for the electrochemical degradation of low-concentration PFOA usingβ-PbO_(2)REM.

关键词： Perfluorooctanoic acid β-PbO_(2) Reactive electrochemical membrane Electrochemical oxidation

稀疏视觉SLAM对平面激光雷达传感的稠密化模拟

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机器人 2018年第3期40卷 273-281页

作者：陈炜楠朱蕾张宏林旭滨管贻生广东工业大学机电工程学院广东广州510006

为了解决稀疏特征点VSLAM(visual simultaneous localization and mapping)由于其构图稀疏性,在视觉导航应用方面的短板,提出一种高斯滤波插值的方法对其特征点进行稠密化处理,实现对平面激光雷达反馈的模拟.本文利用高斯分布以及迭代... 详细信息

为了解决稀疏特征点VSLAM(visual simultaneous localization and mapping)由于其构图稀疏性,在视觉导航应用方面的短板,提出一种高斯滤波插值的方法对其特征点进行稠密化处理,实现对平面激光雷达反馈的模拟.本文利用高斯分布以及迭代滤波实现数据的稠密化,通过建立全局高斯滤波以及局部高斯分布估计,实现对稀疏VSLAM空间点平面投影的数据插补,进而实现对平面激光雷达数据的模拟.仅使用CPU情况下,算法每帧耗时为0.0003 s～0.006 s,插值结果相对误差为7.956%.实验证明,该插值方法成功实现了稀疏投影点的稠密化,插补结果与真实激光雷达反馈相似度高,为视觉导航提供了一种有效的前端传感处理方法.

关键词：视觉导航稠密化插值高斯分布

Grain Yield,Biomass Accumulation,and Leaf Photosynthetic Characteristics of Rice under Combined Salinity-Drought Stress

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Rice science 2024年第1期31卷 118-128,I0023页

作者： WEI Huanhe GENG Xiaoyu ZHANG Xiang ZHU Wang ZHANG xubin CHEN Yinglong HUO Zhongyang ZHOU Guisheng MENG Tianyao DAI Qigen Jiangsu Key Laboratory of Crop Cultivation and Physiology/Jiangsu Key Laboratory of Crop Genetics and Physiology/Jiangsu Co-Innovation Center for Modern Production Technology of Grain Crops/Key Laboratory of Saline-Alkali Soil Reclamation and Utilization in Coastal Areas the Ministry of Agriculture and Rural Affairs of China/Research Institute of Rice Industrial Engineering TechnologyYangzhou UniversityYangzhou 225009China Institute of Agricultural Science and Technology Development/Joint International Research Laboratory of Agriculture and Agri-Product Safety the Ministry of Education of ChinaYangzhou UniversityYangzhou 225009China

Simultaneous stresses of salinity and drought often coincide during rice-growing seasons in saline lands,primarily due to insufficient water resources and inadequate irrigation ***,combined salinity-drought stress poses a major threat to rice *** this study,two salinity levels(NS,non-salinity;HS,high salinity)along with three drought treatments(CC,control condition;DJ,drought stress imposed at jointing;DH,drought stress imposed at heading)were performed to investigate their combined influences on leaf photosynthetic characteristics,biomass accumulation,and rice yield ***,drought,and their combination led to a shortened growth period from heading to maturity,resulting in a reduced overall growth *** yield was reduced under both salinity and drought stress,with a more substantial reduction under the combined salinity-drought *** combined stress imposed at heading caused greater yield losses in rice compared with the stress imposed at ***,the combined salinity-drought stress induced greater decreases in shoot biomass accumulation from heading to maturity,as well as in shoot biomass and nonstructural carbohydrate(NSC)content in the stem at heading and ***,it increased the harvest index and NSC remobilization *** and drought reduced the leaf area index and SPAD value of flag leaves and weakened the leaf photosynthetic characteristics as indicated by lower photosynthetic rates,transpiration rates,and stomatal *** reductions were more pronounced under the combined ***,drought,and especially their combination,decreased the activities of ascorbate peroxidase,catalase,and superoxide dismutase,while increasing the contents of malondialdehyde,hydrogen peroxide,and superoxide *** results indicated a more significant yield loss in rice when subjected to combined salinity-drought *** individual and combined stresses of salinity and dro

关键词： antioxidant defense system combined salinity-drought stress drought stress photosynthetic characteristics rice salinity stress

Qinghai Petroleum Administration Has Set Its Near-Term Exploration Target

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China Oil & Gas 1996年第3期3卷 192-192页

作者： $$$$lin xubin

ＱｉｎｇｈａｉＰｅｔｒｏｌｅｕｍＡｄｍｉｎｉｓｔｒａｔｉｏｎＨａｓＳｅｔＩｔｓＮｅａｒ－ＴｅｒｍＥｘｐｌｏｒａｔｉｏｎＴａｒｇｅｔＬｉｎＸｕｂｉｎＯｎｔｈｅｂａｓｉｓｏｆａｎｏｖｅｒａｌｌｅｖａｌｕａｔｉｏｎｆｏｒｎ... 详细信息

ＱｉｎｇｈａｉＰｅｔｒｏｌｅｕｍＡｄｍｉｎｉｓｔｒａｔｉｏｎＨａｓＳｅｔＩｔｓＮｅａｒ－ＴｅｒｍＥｘｐｌｏｒａｔｉｏｎＴａｒｇｅｔＬｉｎＸｕｂｉｎＯｎｔｈｅｂａｓｉｓｏｆａｎｏｖｅｒａｌｌｅｖａｌｕａｔｉｏｎｆｏｒｎａｔｕｒａｌｇａｓｅｘｐｌｏｒａｔ...

关键词： Qinghai Petroleum Administration Has Set Its Near-Term Exploration Target

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3D打印技术在高超声速技术领域的应用研究

战术导弹技术 2018年第4期 105-109页

作者：林旭斌王晖娟北京海鹰科技情报研究所北京100074

分析了新兴的3D打印技术的优点,指出其在制备复杂构型件时具有整体性好、加工周期短等独特优势,提出将其应用于高超声速飞行器研究领域解决制造难题。根据国外3D打印技术的应用进展,依次介绍了该技术在高超声速飞行器的分系统、零部件... 详细信息

分析了新兴的3D打印技术的优点,指出其在制备复杂构型件时具有整体性好、加工周期短等独特优势,提出将其应用于高超声速飞行器研究领域解决制造难题。根据国外3D打印技术的应用进展,依次介绍了该技术在高超声速飞行器的分系统、零部件、材料等多个层级产品上的应用,为未来高超声速领域研究提供参考。

关键词： 3D打印高超声速技术分系统零部件材料

气力滚筒式蔬菜穴盘播种机吸排种动力学模型的研究

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农业工程学报 2008年第1期24卷 141-146页

作者：夏红梅李志伟牛菊菊林叙彬华南农业大学工程学院广州510642 广州市花都区理工职业技术学院广州510800

为设计结构合理的气力滚筒式排种器,按单刚体系统对种子的吸排种过程建立动力学模型,结合试验研究影响吸排种效果的主要因素。在吸附阶段,选用合适的滚筒材料,提高种子与滚筒间的摩擦系数,适当增大气流量,减小种子与吸孔的距离,可以大... 详细信息

为设计结构合理的气力滚筒式排种器,按单刚体系统对种子的吸排种过程建立动力学模型,结合试验研究影响吸排种效果的主要因素。在吸附阶段,选用合适的滚筒材料,提高种子与滚筒间的摩擦系数,适当增大气流量,减小种子与吸孔的距离,可以大大提高吸附效果。为保证种子能随滚筒转到排种位置,需限制滚筒的最大圆周速度,为此滚筒直径尺寸应适中,滚筒上吸孔按种子平均直径设计,并应合理调节吸种气腔内的真空度。在排种阶段,应优化设计滚筒气腔结构,使每行排种孔的流场分布尽量均匀,以尽量减小射流场对排种穴距不均匀的影响。

关键词：播种机排种器气力动力学模型