Clinical characteristics and prognosis analysis in septic patients with a high level of serum procalcitonin
会议名称：《第四届重症心脏全国学术大会暨第五届西湖重症医学大会、2019年浙江省重症医学学术大会（重症心脏-心与心外器官)》
会议日期：2019年
学科分类：100218[医学-急诊医学] 1002[医学-临床医学] 1010[医学-医学技术（可授医学、理学学位）] 10[医学]
关 键 词：High level of serum PCT(>100μg/L) Sepsis Clinical characteristics Prognostic factors
摘 要：Background:Although the application of serum procalcitonin(PCT) in guiding the diagnosis and treatment of sepsis becomes more and more widely,its significance in a subgroup of septic patients with a high level of serum PCT(100μg/L) remains largely ***,we investigated the clinical characteristics and prognosis of such ***:A retrospective study for septic patients with a high level of serum PCT within 48 hours of hospitalization was conducted in our hospital from February 2013 to December *** characteristics including the demographics,main laboratory examinations and outcomes were extracted from the medical *** patients were divided into survivors and non-survivors based on 28-day *** differences of these variables were compared between groups of survivors and non-survivors.A multi-factorial logistic regression analysis was used for the evaluation of independent risk factors of ***:149 cases of such septic patients were *** were 98 males and 51 females with an average age of 63(52,77) years.98(65.8%) patients were treated in intensive care unit(ICU),and 51(34.2%) patients were treated in general *** total mortality rate was 32.2%(48/149).The median acute physiology and chronic health evaluation II(APACHE II) score was 15(11,19),and the median sequential organ failure assessment(SOFA) score was 10(7,14).The APACHE II [20(18,27) vs.14(10,16),P0.001]and SOFA scores [14(12,18) vs.8(6,11),P0.001],and the incidence of complications including multiple organ dysfunction syndrome(MODS)(87.5% vs.37.6%,P0.001),septic shock(100% vs.60.4%,P0.001) and respiratory failure(72.9% vs.38.6%,P0.001) were significantly higher in non-survivors than in *** addition,some laboratory indexes including liver dysfunction,coagulation dysfunction,levels of myocardial enzymes and lactic acid were higher in non-survivors than in survivors(all P0.05),whereas the platelet(PLT) count was significantly lowe