A survey of Sleep disturbance after COVID-19 vaccination
作者单位：Xuanwu Hospital Capital Medical University
会议名称：《中国睡眠研究会第十五届全国学术年会》
会议日期：2023年
学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1002[医学-临床医学] 100401[医学-流行病与卫生统计学] 10[医学]
摘 要：Objective: To describe the incidence of sleep disturbance after COVID-19 vaccination and explore the relevant risk ***: An online questionnaire survey was conducted from December 2021 to February 2022, by collecting the nationwide data of participant aged 18-65 years who had received the COVID-19 vaccines, regardless of the vaccine *** there was no large-scale COVID-19 infection or lockdown in China during this period, the data is valuable to analyze the relationship between COVID-19 vaccination and sleep ***: 10739 participants with qualified replies were included in the analysis.8748(81.5%) reported no sleep change after vaccination, 1495(13.9%) reported only hypersomnia, 401(3.7%) reported only insomnia, and 95(0.9%) reported *** logistic regression showed comorbidities, self-reported prior insomnia, and sleep disturbing factors were moderately associated with only hypersomnia or only insomnia regardless of the vaccine *** highest incidence of hypersomnia was after the 1st dose(11.4%) and the highest incidence of insomnia was after the 3rd dose(3.7%).The most prevalent patterns of sleep change were hypersomnia after both doses(5.6%) and hypersomnia after 1st dose but no change after 2nd dose(5.4%).Further analysis of interval between onset of hypersomnia and the vaccination as well as duration of hypersomnia after the initial two doese indicated that, the intervals were shorter and the durations were longer after 2nd dose than 1st dose in patients with recurrent episodes of ***: In our observation, hypersomnia was the most frequently reported symptom after COVID-19 *** hypersomnia after the initial two doses might be associated with inflammation after COVID-19 vaccination.