Clarifying sleep characteristics and analyzing risk factors of sleep disorders to promote a predictive, preventive, and personalized medicine in patients with burn scars
作者单位：Shanghai Changhai Hospital
会议名称：《中国睡眠研究会第十五届全国学术年会》
会议日期：2023年
摘 要：Purpose This study assessed sleep quality in patients with burn scars and investigated risk factors of sleep disorders to guide clinical *** the strategy of predictive, preventive, and personalized medicine(PPPM/3PM), we proposed that risk assessment based on clinical indicators could prompt primary prediction, targeted prevention, and personalized interventions to improve the management of sleep disorders present in patients with burn *** This retrospective study recruited patients with burn scars and healthy volunteers from the Shanghai Burn Treatment *** information and data, including demographic characteristics, scar evaluation,and sleep quality, were obtained through the hospital information system, classical scar scale, and self-report *** quality was assessed using the Pittsburgh Sleep Quality Index(PSQI) and monitored using a cardiopulmonary-coupled *** and pruritus were assessed using the visual analog scale(VAS).Scar appearance was assessed using the modified Vancouver scar scale(mVSS).Results The sample was comprised of 128 hypertrophic scar(HS) patients, with 61.7% males, a mean age of 41.1 ± 11.6 years, and burn area of 46.2 ± 27.9% total body surface area(TBSA).Patients with PSQI ≥ 7 accounted for 76.6%, and the global PSQI score was 9.4 ± *** sleep data showed that initial enter deep sleep time, light sleep time, awakening time, light sleep efficiency, and sleep apnea index were higher but deep sleep time, sleep efficiency, and deep sleep efficiency were lower in HS patients than that in healthy *** univariate analysis showed that age, hyperplasia time of scar, narrow airway, microstomia, VAS for pain and pruritus, and mVSS total(comprised of pigmentation, vascularity, height and pliability) were associated with the PSQI score(p 0.1).Multivariable linear regression showed narrow airway, VAS for pain and pruritus, and mVSS specifically height, were the ris