BDNF secreted from nerve fibroblasts promotes neurite outgrowth of motoneurons by activating ERK and AKT pathway
作者单位：Key Laboratory of Neuroregeneration of Jiangsu and Ministry of EducationNantong University
会议名称：《中国解剖学会2021年年会》
会议日期：2021年
学科分类：0710[理学-生物学] 07[理学] 071006[理学-神经生物学]
摘 要：Peripheral nerve fibroblasts play an important role in the process of nerve development and regeneration.The present study revealed that fibroblasts with different tissue sources,such as peripheral nerve fibroblasts (N-Fbs) and cardiac Fbs (C-Fbs),exerted distinct effects on motoneurons.Compared to C-Fbs,N-Fbs significantly promoted neurite outgrowth of motoneurons in vitro.