Transcatheter Closure of Perimembranous Ventricular Septal Defects Using an Occluder: 5-Year Outcomes
作者单位：The Second Affiliated Hospital of Wenzhou Medical University
会议名称：《2019年浙江省医学会儿科学分会学术大会》
会议日期：2019年
学科分类：1002[医学-临床医学] 100202[医学-儿科学] 10[医学]
摘 要：Background Transcatheter closure of perimembranous ventricular septal defects is one of the greatest challenges in interventional cardiology. Long-term follow-up data are limited. This report presents our experience with transcatheter closure of perimembranous ventricular septal defects using an *** 253 patients included in the database of the Second Affiliated Hospital and Yuying Children’s Hospital from January 2011– December 2015 with transcatheter closure of perimembranous ventricular septal defects and discharged from follow-up. All patients were invited for clinical and transthoracic echocardiography, electrocardiogram, and thoracic radiography *** Device implantation was successful in 252 of 253 patients(99.6%). The median age was 42 months(range 27 months–18 years). The patients were followed for 6–60 months. The mean defect diameter was 3.5 ± 1.4 mm and the mean size of the ventricular septal defect rim below the aortic valve was 3.7 ± 1.8 mm. The mean diameter of the devices used was 4 mm. Thirty-seven patients developed arrhythmia after the procedure and recovered within 24 months;four patients had hemolysis and four had moderate tricuspid valve regurgitation. No other serious adverse event occurred during the follow-up *** Transcatheter closure of perimembranous ventricular septal defects using an occluder is safe and effective in most patients. Additional studies with larger cohorts and longer follow-up periods are needed to further evaluate the safety of this method. The use of a smaller occluder may shorten the operation time, decreasing the incidence of postoperative arrhythmia.