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Women successfully treated for severe intrahepatic cholestas...

Women successfully treated for severe intrahepatic cholestasis of pregnancy do not have increased risks for adverse perinatal outcomes

作     者:LiuMin Yang jielian ChenChong ZhangShuye 

作者单位:Department of OB/GYN Shanghai Public Health Clinical Center 

会议名称:《2019长三角围产医学学术会议暨浙江省围产医学学术大会》

会议日期:2019年

学科分类:1002[医学-临床医学] 100211[医学-妇产科学] 10[医学] 

摘      要:Background:Intrahepatic cholestasis of pregnancy (ICP) increases adverse perinatal outcome (APO) ***:To investigate whether successful treatment of severe ICP reduces APO ***:This retrospective, single-center study enrolled consecutive Chinese women with ICP (singleton delivery at≥37 weeks) between August 2013 and June 2016. Patients were divided into mild ICP (serum bile acids [SBA]≤40μmol/L throughout pregnancy) and severe ICP (SBA initially40μmol/L but fell after ursodeoxycholate therapy) groups. Clinical characteristics, laboratory investigations and maternal/neonatal outcomes were assessed.

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