Retinoblastoma binding protein 4 represses HIV-1 long terminal repeat-mediated transcription by recruiting NR2F1 and histone deacetylase
作者单位：Tongde Hospital of Zhejiang Province The Second Department of Infectious DiseaseXixi Hospital of Hangzhou The First Affiliated HospitalCollege of MedicineZhejiang University Center for Translational MedicineThe Affiliated Hospital of Hangzhou Normal University Department of Clinical LaboratoryXixi Hospital of Hangzhou
会议名称：《2019年浙江省检验医学学术大会》
会议日期：2019年
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
摘 要：Human immunodeficiency virus(HIV) transcription is closely associated with chromatin remodeling. Retinoblastoma binding protein 4(RBBP4) is a histone chaperone implicated in chromatin remodeling. However, the role of RBBP4 in HIV-1 infection and the underlying mechanism remain elusive. In the present study,