Clinical significance of heart rate variability change in patients with pancreatic cancer
作者单位：Tai Zhou Hospital of Zhe Jiang Province
会议名称：《2018年浙江省外科学学术年会》
会议日期：2018年
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
关 键 词：pancreatic cancer heart rate variability vagal nerve stimulation CRP
摘 要：Objective :To evaluate the clinical value of heart rate variability change in the patients with pancreatic *** :Totally 518 clinical cases from January 2008 to May 2013 were retrospectively analyzed in the Tai Zhou Hospital of Zhe Jiang *** examined the moderating effects of gender,age,cancer stages and distant metastasis on HRV including standard deviation of NN intervals(SDNN) and root mean square of successive differences(RMSSD).We tested statistical significance of C-ractive protein(CRP) and tumor diameter between low HRV group and high HRV group,using the cut-off of SDNN=20 *** :Cancer patients with early stage had significant higher HRV than those with advanced stages(P0.001).Cancer patients without metastasis had significant higher HRV than those with metastasis(P=0.011).CRP was higher in low HRV group than that in high HRV group(P=0.008).Conclusion :The later the stage of pancreatic cancer patients is,the more the index of HRV *** may be the mechanism that vagal nerve excitement inhibits inflammatory reaction.