Microglia regulate RVLM-projecting PVN neuronal activity
作者单位：The Second Affiliated HospitalZhejiang Chinese Medical University Department of NeurologyZhejiang Hospital Department of Physiologyand Department of Cardiology of the Second Affiliated HospitalZhejiang University School of Medicine Zhejiang Provincial Key Lab of GeriatricsZhejiang Hospital Department of Intensive Care UnitZhejiang Hospital Department of Cardiology of the Second Affiliated Hospitaland Institute of Translational MedicineZhejiang University School of Medicine BGI GenomicsBGI-Shenzhen
会议名称：《2019年浙江省神经病学学术大会》
会议日期：2019年
学科分类：0710[理学-生物学] 07[理学] 071006[理学-神经生物学]
摘 要：Microglia,the primary resident immune cells in the CNS,communicate with neurons very *** previous studies show that activated microglia are involved in neurogenic *** the present study,we are investigating the mechanism by which microglia regulate RVLM-projecting PVN neuronal activity in resting *** male transgenic CD11b-DTR mice were randomly assigned into two groups:sham control and diphtheria toxin (DT) groups,which received ICV infusion of saline or DT (depletion ofmicroglia) respectively.