A serine protease homologue Bombyx mori scarface induces a short and fat body shape in silkworm
作者单位：State Key Laboratory of Silkworm Genome BiologyKey Laboratory of Sericultural Biology and Genetic BreedingMinistry of AgricultureSouthwest University Institute of Entomology and Molecular BiologyCollege of Life SciencesChongqing Normal University
会议名称：《中国蚕学会第十届青年学术研讨会》
会议日期：2019年
学科分类：090504[农学-特种经济动物饲养（含：蚕、蜂等）] 0905[农学-畜牧学] 09[农学]
摘 要：Body shape is one of the most prominent and basic characteristics of any *** insects,abundant variations in body shape can be observed both within and amongst ***,the molecular mechanism underlying body shape fine-tuning is very complex and has been largely unknown until *** the silkworm Bombyx mori,the tubby（tub） mutant has an abnormal short fat body shape and the abdomen of tub larvae expands to form a fusiform body *** investigation revealed that the body length was shorter and the body width was wider than that of the Dazao ***,this mutant is a good model for studying the molecular mechanisms of body shape *** positional cloning,we identified a gene encoding the serine protease homologue,*** scarface（Bmscarface）,which is associated with the tub *** analysis revealed a specific 312-bp deletion from an exon of Bmscarface in the tub *** addition,recombination was not observed between the tub and Bmscarface ***,RNA interference of Bmscarface resulted in the tub-like *** results indicate that Bmscarface is responsible for the tub mutant *** is the first study to report that mutation of a serine protease homologue can induce an abnormal body shape in insects.