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The elevated serum levels of Calcineurin and NFAT1 in childr...

The elevated serum levels of Calcineurin and NFAT1 in children with Kawasaki disease

作     者:Yameng Sun Yanqi Qi Ying Wang Songling Fu Wei Wang Chunhong Xie Yiying Zhang Fangqi Gong 

作者单位:Children’s Hospital of Zhejiang University School of Medicine 

会议名称:《2018年浙江省医学会儿科学分会学术年会》

会议日期:2018年

学科分类:1002[医学-临床医学] 100202[医学-儿科学] 10[医学] 

摘      要:Background:To evaluate serum calcineurin (CaN) and nuclear factor of activated T-cells 1 (NFAT1) levels in patients with Kawasaki disease (KD).Methods:Serum levels of CaN and NFAT1 were measured by enzyme-linked immunosorbent assay method in66 healthy children and 74 KD patients at acute,afebrile and subacute ***:The serum levels of CaN and NFAT1 increased significantly in the acute stage,and decreased progressively in the afebrile and subacute stage,along with the reduction of C-reactive protein,white blood cells *** in the acute stage,

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