Toward Unified Total Synthesis of Tigliane and Daphanane Natural Products
作者单位：Frontier Institute of Science and Technology Xi’an Jiaotong University
会议名称：《中国化学会第八届天然产物全合成青年学术研讨会》
会议日期：2019年
学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学]
摘 要：正Tiglianes and daphnanes are two bio-genetically correlated families of diterpenoids isolated from plants.1,2 Structurally, they are highly oxidized compact polycyclic compounds as shown by the representative members in Fig. 1. These molecules share a densely substituted [5,7,6] tricyclic core that features C4,C10-and C8,C9 double trans configurations at ring junctions and multiple contiguous stereocenters including three tertiary alcohols.