Genome-wide Analysis of Position Effects on Gene Expression at Single-cell Resolution
作者单位:State Key Laboratory of Molecular Developmental BiologyInstitute of Genetics and Developmental BiologyChinese Academy of Sciences
会议名称:《第五届中国秀丽线虫大会》
会议日期:2018年
学科分类:0710[理学-生物学] 07[理学] 08[工学] 09[农学] 071007[理学-遗传学] 0901[农学-作物学] 0836[工学-生物工程] 090102[农学-作物遗传育种]
摘 要:正Expression of identical transgene could be highly variable,depends on the genomic location of integration,a phenomenon known as position *** in Drosophila have showed that characterization of position effects is effective to decipher chromatin activity and epigenetic regulation of gene expression.