Solvent-free D-proline Catalyzed Synthesis of N,O-Acetal Compounds
作者单位：东华理工大学 Department of Applied ChemistryEast China University of Technology
会议名称：《中国化学会·第十六届全国有机合成化学学术研讨会》
会议日期：2019年
学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学]
关 键 词：D-proline N,O-acetal compounds green chemistry solvent-free room temperature
摘 要：N,O-acetal compound is present in many biologically active natural products,and N,O-acetal compound also can be used as a synthetic material for some reaction, In this paper,a convenient method for synthesizing N,O-acetal compounds was developed,using aromatic aldehyde,urea and alcohol as materials,and D-proline as catalyst.A series of N,O-acetal compounds were synthesized with good yields after reaction for 30 h at room temperature.