Neuroprotective effect of a novel gastrodin derivative against ischemic brain injury:involvement of peroxiredoxins and TLR4 signaling inhibition
作者单位：West China School of PharmacySichuan University
会议名称：《第十一届海峡两岸心血管科学研讨会、2017年全国心脑血管药理学术会议、中国卒中学会第一次新药研讨会》
会议日期：2017年
学科分类：1002[医学-临床医学] 100204[医学-神经病学] 10[医学]
关 键 词：Neuroprotective effect of a novel gastrodin derivative against ischemic brain injury:involvement of peroxiredoxins and TLR4 signaling inhibition TLR
摘 要：Objective:The inhibition of extracellular inflammatory peroxiredoxin(Prx) signaling appears to be a potential therapeutic strategy for neuroinflammatory injury after acute ischemic ***(Gas) is a phenolic glycoside that is used for the treatment of cerebral ischemia,accompanied by regulation of the autoimmune inflammatory ***:The present study investigated the neuroprotective effects of Gas and its derivative,Gas-D,