Whole brain mapping of sortilin relative to Ab and tau pathologies in end-stage Alzheimer’s disease
作者单位：Department of Anatomy andNeurobiologyCentral South University Xiangya School of Medicine
会议名称：《中国解剖学会2019年年会》
会议日期：2019年
学科分类：1002[医学-临床医学] 100203[医学-老年医学] 10[医学]
摘 要：正Much research on Alzheimer’s disease （AD） has been focused on b-amyloid （Ab） and phosphorylated tau （p-Tau）,major constituents of extracellular plaques and intraneuronal neurofibrillary tangles （NFTs）.Recently, putative Cterminal fragments of sortilin were seen to deposit as plaque-like lesions,while other studies suggested potential