Aberrant oligodendroglial-vascular interactions disrupt the blood brain barrier triggering central nervous system inflammation
作者单位：Department of Histology and EmbryologyCollaborative Innovation Center for Brain ResearchThird Military Medical University Department of PediatricsUniversity of California at San Francisco Department of NeurologyUniversity of California at San Francisco
会议名称：《中国解剖学会2019年年会》
会议日期：2019年
学科分类：1002[医学-临床医学] 100204[医学-神经病学] 10[医学]
摘 要：正Disruption of the blood brain barrier （BBB） is critical to initiation and perpetuation of disease in multiple sclerosis （MS）.We report here an interaction between oligodendroglia and vasculature in MS that distinguishes human white matter injury from normal rodent *** perivascular oligodendrocyte progenitor cells （OPCs）,representing an