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TCMID 2.0:a comprehensive resource for TCM

TCMID 2.0:a comprehensive resource for TCM

作     者:Lin Huang Yan Shi Yiran Yu Duoli Xie Huanlong Liu Tieliu Shi Chengping Wen 

作者单位:TCM Clinical Basis InstituteZhejiang Chinese Medicine University Center for Bioinformatics and Computational Biologyand The Institute of Biomedical SciencesCollege of Life ScienceEast China Normal University 

会议名称:《“农业健康与环境”组学大数据整合生物信息学研讨会》

会议日期:2017年

学科分类:1006[医学-中西医结合] 1005[医学-中医学] 10[医学] 

关 键 词:Traditional Chinese Medicine(TCM) database mass spectrometry network 

摘      要:As a traditional medical intervention in Asia and a complementary and alternative medicine in western countries,Traditional Chinese Medicine(TCM) is capturing worldwide attention in life science *** Chinese Medicine Integrated Database(TCMID),which was originally launched in 2013,was a comprehensive database aiming at TCM’s modernization and *** has been highly recognized among pharmacologists and scholars in TCM *** latest release,TCMID 2.0(http://***/tcmid/),replenished the preceding database with 18,203 herbal ingredients,15 prescriptions,82 related targets,1,354 drugs,1,572 diseases and numerous new connections between *** that chemical changes might take place in decocting process of prescriptions,which may result in new ingredients,new data containing the prescription ingredients was collected in current *** addition,778 herbal mass spectrometry(MS) spectra related to 170 herbs were appended to show the variation of herbal quality in different origin and distinguish genuine medicinal materials from common ones while 3,895 MS spectra of 729 ingredients were added as the supplementary materials of component *** the significant increase of data,TCMID 2.0 will further facilitate TCM’s modernization and enhance the exploration of underlying biological processes that are response to the diverse pharmacologic actions of TCM.

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