Numerical simulations of conventional radiotherapy and targeted intraoperative radiotherapy for tumor invasion
作者单位：University of Shanghai for Science and Technology
会议名称：《第十二届全国生物力学学术会议暨第十四届全国生物流变学学术会议》
会议日期：2018年
学科分类：0831[工学-生物医学工程（可授工学、理学、医学学位）] 1001[医学-基础医学(可授医学、理学学位)] 08[工学] 1010[医学-医学技术（可授医学、理学学位）] 100106[医学-放射医学] 10[医学]
基 金：National NaturalScience Foundation of China:11502146 Shanghai Natural Science Foundation:15ZR1429600
摘 要：Objective Radiotherapy has been used for treatment of cancer almost since it was discovered;hence it’s important to understand the biological effects that different radiotherapy brings. Methods A two dimensional mathematical model of a solid tumor growth and invasion and response to fractioned radiotherapeutic schemes is presented in this paper. The tumor cells and tissue survival probabilities following irradiation are calculated by the established linear quadratic model (LQ model). Results Our model simulates the effects of conventional ex-