In silico systems evaluation of drug-induced cardiotoxicity
作者单位：Center for Public Health InformaticsSchool of Public HealthXinxiang Medical University
会议名称：《第二次全国计算毒理学学术会议暨中国毒理学会第一届计算毒理专业委员会第二次会议》
会议日期：2018年
学科分类：1007[医学-药学(可授医学、理学学位)] 1006[医学-中西医结合] 100706[医学-药理学] 100602[医学-中西医结合临床] 10[医学]
关 键 词：Cardiotoxicity CiPA Computer Modeling Arrhythmias
摘 要：Drug-induced cardiotoxicity,*** lethal arrhythmia Torsade de Pointes(TdP),has been recognized as a critical issue since the very early stage of drug design and ***,unexpected post-marketing occurrence of cardiotoxic effects remains a leading cause of drug withdrawn and *** studies have