Metagenomic Study Suggests That the Gut Microbiota of the Giant Panda(Ailuropoda melanoleuca) May Not Be Specialized for Fiber Fermentation
作者单位：Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan ProvinceSichuan Agricultural University Division of AgricultureDepartment of Animal ScienceUniversity of Arkansas Animal Nutrition InstituteSichuan Agricultural University College of Animal Science and TechnologySichuan Agricultural University China Conservation and Research Center for the Giant Panda Chengdu ZooChengdu Institute of Wildlife
会议名称：《中国畜牧兽医学会动物微生态学分会第五届第十三次全国学术研讨会》
会议日期：2018年
学科分类：090601[农学-基础兽医学] 09[农学] 0906[农学-兽医学]
基 金：supported by the "1000-Talent Program" in Sichuan and Science Foundation for Youths of Sichuan Province(2013JQ0014) The National Natural Science Foundation of China (31471997)
关 键 词：Giant panda Gut microbiota metagenomics enzyme activity diet adaptability
摘 要：Bamboo-eating giant panda(Ailuropoda melanoleuca) is an enigmatic species,which possesses a carnivore-like short and simple gastrointestinal tract(GIT).Despite the remarkable studies on giant panda,its diet adaptability status continues to be a matter of *** resolve this puzzle,we investigated the functional potential of the giant panda gut microbiome using shotgun metagenomic sequencing of fecal *** also compared our data with similar data from other animal species representing herbivores,carnivores,and omnivores from current and earlier *** found that the giant panda hosts a bear-like gut microbiota distinct from those of herbivores indicated by the metabolic potential of the microbiome in the gut of giant pandas and other ***,the relative abundance of genes involved in cellulose-and hemicellulose-digestion,and enrichment of enzymes associated with pathways of amino acid degradation and biosynthetic reactions in giant pandas echoed a carnivore-like *** significantly,the enzyme assay of the giant panda’s feces indicated the lowest cellulase and xylanase activity among major herbivores,shown by an in-vitro experimental assay of enzyme activity for cellulose and *** of our results consistently indicate that the giant panda is not specialized to digest cellulose and hemicellulose from its bamboo diet,making the giant panda a good mammalian model to’ study the unusual link between the gut microbiome and *** increased food intake of the giant pandas might be a strategy to compensate for the gut microbiome functions,highlighting a strong need of conservation of the native bamboo forest both in high-and low-altitude ranges to meet the great demand of bamboo diet of giant pandas.