Interrupted Pummerer Reaction Mediated Glycosylation: Synthesis of Resin Glycosides Murucoidin V and Tricolorin A
作者单位：School of Pharmacy Huazhong University of Science and Technology
会议名称：《中国化学会第十四届全国有机合成化学学术研讨会》
会议日期：2017年
学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学]
基 金：国家自然科学基金(No.21272082 21472054 21672077 )资助项目
关 键 词：interrupted Pummerer reaction total synthesis resin glycosides glycosylation
摘 要：Recently we have developed an interrupted Pummerer reaction mediated glycosylation by employing O-2-（2-propylsulfinyl）benzyl or S-2-（2-propylsulfinyl）benzyl as leaving group, which allowed glycosylation of both armed and disarmed donors with various glycosyl acceptors. In this paper, we described the convergent synthesis of Resin glycosides Murucoidin V and Tricolorin A utilizing newly developed glycosyl donors.