Hydrodehalogenation of Activated Alkyl Bromides with Water Catalyzed by Rhodium Porphyrin Complex
作者单位：Department of ChemistryThe Chinese University of Hong Kong
会议名称：《中国化学会第四届卟啉与酞菁学术研讨会》
会议日期：2017年
学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学]
基 金：Research Grants Council of Hong Kong SAR(14300214) the Hong Kong PhD Fellowship for financial support
关 键 词：hydrodehalogenation of activated alkyl bromides water as the hydrogen source without any sacrificial reductant
摘 要：For the reductive hydrodebromination,the reductants are usually H gas,alcohols,hydrosilanes,metal hydrides and so ***,as a green,economically more attractive reducing agent,is generally believed unlikely to be the hydrogen atom donor to carbon-centered radicals due to the high bond dissociation energy of H-OH bond(118 kcal/mol).Weakening this H-OH bond by the coordination of HO to a Lewis acid makes HO as a hydrogen atom donor *** examples employed CpTiCl,BMe3 or SmI as the Lewis acid.1 However,it involves a stoichiometric amount of the Lewis ***,based on our earlier success of employing water as the hydrogen source for hydrogenating carbon-carbon σ-bonds,2 we disclose a rhodium porphyrin complex catalyzed hydrodebromination of activated alkyl bromides with water as the attractive hydrogen source without any sacrificial reductant.