Isolation and structural characterization of related impurities in andrographolide sodium bisulphite
作者单位：State Key Laboratory of Natural Medicines China Pharmaceutical University Department of Natural Medicinal Chemistry China Pharmaceutical University Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research Jinan University
会议名称：《中国化学会第十届全国天然有机化学学术会议》
会议日期：2014年
学科分类：1007[医学-药学(可授医学、理学学位)] 10[医学]
摘 要：正Andrographolide sodium bisulphite（ASB）,widely used in China for the treatment of bacterial infections,is a water-soluble sulfonated derivative of andrographolide,an important diterpenoid lactone isolated from Andrographis *** chemical investigation of ASB bulk drug resulted in the isolation of four new related impurities,3,12,13,15,19-pentahydroxy-8,14-