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Gene Expression Profiling and Prognosis in Chronic Lymphocyt...

Gene Expression Profiling and Prognosis in Chronic Lymphocytic Leukemia

作     者:YAalto WEI-Rifai LVilpo JOllila BNagy MVihinen JVilpo SKnuutila 

作者单位:Department of Medical GeneticsHaartman Institute and Helsinki University Central Hospital Department of Medical GeneticsHaartman Institute and Helsinki University Central Hospital Division of Biochemistry Department of Biosciences University of Helsinki Helsinki Department of Clinical Chemistry Department of Medical GeneticsHaartman Institute and Helsinki University Central HospitalGenetic Laboratory Faculty of MedicineSemmelweis UniversityBudapestHungary Institute of Medical Technologyand University of TampereTampere University HospitalTampereFinland Division of Biochemistry Department of Biosciences University of Helsinki Helsinki Department of Medical GeneticsHaartman Institute and Helsinki University Central Hospital 

会议名称:《Asian-Pacific Conference of Tumor Biology 2001》

会议日期:2001年

学科分类:1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

摘      要:正Chronic lymphocytic leukemia(CLL)is a heterogeneous disease with regard to its clinical *** of the methods currently available for prognostic assessment in CLL do not allow accurate pre-diction of the risk of disease progression in individual *** receotly developed cDNA array tech-nique provides a unique opportunity to study gene expression in various *** identify newmolecular markers for prognostication of CLL patients,we analyzed cDNA arrays by using hierarchicalclustering and standard statistic t-test on 34 CLL ***19 positive B cells purified from human

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