The Ubiquitination of SM22α Regulate G6PD-induced Vascular Oxidant Stress
作者单位:Department of Biochemistry and Molecular BiologyInstitute of Basic MedicineHebei Medical University
会议名称:《第八届全国医学生物化学与分子生物学第五届全国临床应用生物化学与分子生物学2013华东六省一市生物化学与分子生物学联合学术研讨会》
会议日期:2013年
学科分类:1001[医学-基础医学(可授医学、理学学位)] 100104[医学-病理学与病理生理学] 10[医学]
摘 要:Background The phenotypes of vascular smooth muscle cells(VSMCs)can switch between differentiated and dedifferentiated states,which are essential for repair of vascular *** have demonstrated that smooth muscle(SM)22a inhibits cell proliferation via blocking Ras-ERKl/2 signaling in VSMCs and in injured *** recent studies indicate that PKC-mediated SM22a phosphorylation is a novel link between actin cytoskeletal remodeling