Marchantin M:A new inhibitor of proteasome induces autophagic cell death in prostate cancer cells
作者单位：Department of Biochemistry and Molecular BiologyShandong UniversitySchool of Medicine Department of Natural Product ChemistryShandong University School of Pharmaceutical Sciences
会议名称：《华东六省一市生物化学与分子生物学学会-2011年学术交流会》
会议日期：2011年
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
摘 要：We recently reported that marchantin M(Mar M),a cyclic bisbibenzyl compound,was an active agent to induce apoptosis in human prostate cancer,but the molecular mechanisms of action remain largely ***,we demonstrated that Mar M treatment dramatically enhanced LC3B expression and turnover,suggesting that Mar M induced *** cell death was responsible for its cancer cell death-