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The long and short isoforms of tree shrew MITA play distinct...

The long and short isoforms of tree shrew MITA play distinct roles in DNA virus and RNA virus infections

作     者:Xu Ling Yu Dandan Yao Yonggang 

作者单位:Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences& Yunnan ProvinceKunming Institute of Zoology 

会议名称:《第十二届全国免疫学学术大会》

会议日期:2017年

学科分类:1001[医学-基础医学(可授医学、理学学位)] 100102[医学-免疫学] 10[医学] 

关 键 词:MITA Alternative splicing Antiviral innate immunity Tree shrew 

摘      要:Human mediator of IRF3 activation(MITA;also known as STING,TMEM173,MPYS or ERIS)is a key adaptor protein for most DNA-sensing pathways and is critical for RNA virus antiviral innate ***,the role of MITA

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