The role of hydrolethalus syndrome gene HYLS1 in cilia and sperm flagellar formation
作者单位：Key Laboratory of Insect Developmental and Evolutionary BiologyShanghai Institute of Plant Physiology and EcologyChinese Academy of Sciences
会议名称：《中国生理学会生殖科学专业委员会—中国动物学会生殖生物学分会第二次联合学术年会暨“生殖科学专业委员会第二次学术交流会”和“生殖生物学分会第十六次学术年会”》
会议日期：2017年
学科分类：1001[医学-基础医学(可授医学、理学学位)] 100104[医学-病理学与病理生理学] 10[医学]
摘 要：Eukaryotic flagellar and cilia are microtubule-based,structurally similar cell surface protrusions that project from *** centrioles initiate cilia/flagellar formation remains ***1 is an evolutionary conserved centriole *** in human HYLS1 leads to a cilia-related perinatal lethal disorder,hydrolethalus ***,the underlying mechanism of HYLS1 in cilia