The Signaling Pathway Involved in Proton-Sensing Receptor TDAG8 Induced CD147 Expression in the Acidic Condition
作者单位:College of life sciencesInner Mongolia University
会议名称:《第四届泛环渤海生物化学与分子生物学会学术交流会》
会议日期:2013年
学科分类:1001[医学-基础医学(可授医学、理学学位)] 100102[医学-免疫学] 10[医学]
摘 要:Objective:TDAG8(T-cell death-associated gene 8),an orphan GPCR which was up-regulated during the programmed cell death of T-lymphocytes,has been known for a proton-sensing *** several studies have shown that TDAG8 might promote tumor cell migration through improving CD 147 expression on acidic condition,its detailed molecular mechanism is still *** study was carried out to demonstrate