Screening and managing obstructive sleep apnoea in nocturnal heart block patients:An observational study
作者单位：Department of Pulmonary Medicine Zhongshan Hospital Fudan University
会议名称：《中国睡眠研究会第九届学术年会》
会议日期：2016年
学科分类：1002[医学-临床医学] 100213[医学-耳鼻咽喉科学] 10[医学]
关 键 词：Obstructive sleep apnoea heart block Berlin Questionnaire continuous positive airway pressure
摘 要：Background:Nocturnal heart block often occurs in patients with obstructive sleep apnoea(OSA).It is more likely to be undiagnosed in heart block patients who are ignorant of the symptoms of sleep *** Questionnaire(BQ) is a highly reliable way to discover the risk factors of OSA,whereas the validity in sleep-related heart block patients is *** performed an observational study to address these issues and confirmed the potential protective effect of continuous positive airway pressure(CPAP).Methods:Patients who were previously diagnosed with nocturnal heart block with R-R pauses exceeding 2 seconds were retrospective screened from the ECG centre of Zhongshan *** participantscompleted Berlin Questionnaire and underwent polysomnography synchronously with 24-hour Holter monitoring.A cross-sectional analysis was performed to confirm the association between nocturnal arrhythmia and OSA,as well as to assess the diagnostic accuracy of the ***,subjects diagnosed with OSA(apnoea-hypopnoea index 5) underwent 3consecutive days of CPAP *** the third day,patients repeated 24-hour Holter monitoring within the institution of ***:The symptoms of disruptive snoring and hypersomnolence in 72 enrolled patients were more related to the occurrence of nocturnal heart block(r = 0.306,0.226,respectively,p = 0.015,0.019) than syncope(r=0.134,p=0.282) and palpitations(r = 0.106,p= 0.119),which were prominent trait of our study *** sensitivity,specificity,positive and negative predictive value of the BQ at a cut-off point of 5 of AHI for detecting OSA in heart block patients was 81.0%,44.4%,91.07%and 25%.Nocturnal heart block does not appear to occur exclusively in severe sleep *** frequent occurrence of arrhythmias in prominent oxygen desaturation supports the correlation between *** therapy resulted in significant decrease in the average number of episodes of heart block,from 148.58 ±379.44 to 16.07 ±