GENE DELIVERY TO PIG ARTERIES THROUGH COLLAGEN COATED STENTS WITH ANTIBODY-TETHERED GENE
作者单位:The Division of CardiologyChildren’s Hospital of Philadelphia and University of PennsylvaniaPA 19104USA The Division of CardiologyChildren’s Hospital of Philadelphia and University of PennsylvaniaPA 19104USA
会议名称:《The 6th International Conference on Biomedical Engineering and Rehabilitation Engineering》
会议日期:2002年
学科分类:1002[医学-临床医学] 100201[医学-内科学(含:心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
摘 要:正 Stents were formulated with a collagen coating. Anti-adenoviral monoclonalantibodies were covalently bound to the collagen surface. These antibodiesenabled tethering of replication defective adenoviruses through highlyspecific antigen-antibody affinity. We report for the first time successful