Evolution of Anion Relay Chemistry（ARC）: The Design, Synthesis and Validation of New ARC Paradigms with Applications in Complex Molecule Synthesis
作者单位：University of Pennsylvania Department of Chemistry
会议名称：《中国化学会第十一届全国天然有机化学学术会议》
会议日期：2016年
学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学]
基 金：Financial support was provided by NIH(GM-29028 and CA-19033)
摘 要：正Anion Relay Chemistry（ARC）,a robust multi-component synthetic tactic,permits the rapid construction of complex natural andnatural-likemolecules for biomedical *** exploiting various anion（i.e.,charge）relocation tactics via[1,n]-Brook rearrangements,the controlled,sequential assembly of architecturally diverse structures can be achieved by virtue of the latent nucleophilicity of the designed bifunctional ARC linchpins,