FAM3B mediates high glucose-induced vascular smooth muscle cell proliferation and migration via inhibition of mi R-322-5p
作者单位：Jiangsu Key Laboratory for Molecular and Medical Biotechnology and College of Life SciencesNanjing Normal University Jiangsu Key Laboratory of Human Functional Genomics Nanjing Medical University State Key Laboratory of Natural Medicines China Pharmaceutical University
会议名称：《中国生物化学与分子生物学会2016年全国学术会议》
会议日期：2016年
学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
关 键 词：FAM3B vascular smooth muscle cells proliferation migration miR-322-5p
摘 要：The proliferation and migration of vascular smooth muscle cells(VSMCs)play an essential role during the development of atherosclerosis and *** many factors potentially contribute to the abnormal activation of VSMCs,hyperglycemia is generally believed to be a major causative *** the other hand,FAM3B(named PANDER for its secretory form)is a uniquely structured protein strongly expressed within