Autophagy induced by DAMPs facilitates the inflammation response in lungs undergoing ischemia-reperfusion injury through promoting TRAF6 ubiquitination
作者单位:Research Center for Translational Medicine & Institute of Heart Failure Shanghai East Hospital Tongji University School of Medicine
会议名称:《第十一届全国免疫学学术大会》
会议日期:2016年
学科分类:1002[医学-临床医学] 100201[医学-内科学(含:心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
关 键 词:Alveolar macrophages Autophagy DAMPs Lung ischemia-reperfusion injury sterile inflammation
摘 要:Lung ischemia-reperfusion(I/R)injury remains one of the most common complications after various cardiopulmonary *** inflammation response triggered by the released damage-associated molecular patterns(DAMPs)aggravates lung tissue ***,little is known about the role of autophagy in the pathogenesis