Activation of Langerhans Cells Promotes the Inflammation in Imiquimod-induced Psoriasis-like Dermatitis
作者单位：Department of Dermatology Xijing Hospital Fourth Military Medical University
会议名称：《第十一届全国免疫学学术大会》
会议日期：2016年
学科分类：1002[医学-临床医学] 100206[医学-皮肤病与性病学] 10[医学]
关 键 词：Langerhans cells psoriasis inflammation imiquimod activation
摘 要：Objectives:To explore the role of LCs in mouse model of imiquimod(IMQ)-induced psoriasis-like dermatitis using langerin-diphtheria toxin A(DTA)mice that are constitutively deficient in ***:IMQ(Aldara)was painted on the skin of mice to produce psoriasis-like dermatitis,and inflammation was evaluated by gross ear thickness,histopathology,flow cytometry and cytokine *** marrow