Effectofprotein diet intervention on hyperphosphatemiaand nutritional status in patients undergoing dialysis:systematic review and metaanalysis of randomized,controlled trials
作者单位：The First Affiliated Hospitalcollege of MedicineZhejiang University College of Pharmaceutical ScienceZhejiang Chinese Medical University
会议名称：《2015年浙江省医学会临床药学分会、浙江省中西医结合学会中药分会学术会议》
会议日期：2015年
学科分类：0831[工学-生物医学工程（可授工学、理学、医学学位）] 08[工学]
关 键 词：hemodialysis peritoneal dialysis low protein diet hyperphosphatemia,nutritional status metaanalysis
摘 要：Background:Low protein(LP) diet is presumed to be associated with malnutrition in patients undergoinghemodialysis(HD) and peritoneal dialysis(PD),while high protein(HP) intakecan cause an increase in hyperphosphatemia and improvement in nutritional *** effect of protein diet intervention on hyperphosphatemia and nutritional status in HD or PD patientsremains ***:A systematic review and meta-analysis were performed examining all randomized controlled trials(RCTs) of a protein diet intervention for hyperphosphatemia and nutritional statusin PD or HD patients to ***:The search yielded 5 trials including 390 *** analyses showed the serum albumin(SA) of LP group was lower than the HP group(WMD =-1.72,p0.0001),while LP diet with keto acid-supplemented(sLP)was not lower than the HP group(WMD=-0.43,p = 0.63).Conclusion:sLP dietsmaydecrease hyperphosphatemiaand calcium-phosphate product,while keeping stable nutritional status among dialysispatient.